ATE108776T1 - Muscarin-rezeptor-antagonisten. - Google Patents

Muscarin-rezeptor-antagonisten.

Info

Publication number
ATE108776T1
ATE108776T1 AT90917103T AT90917103T ATE108776T1 AT E108776 T1 ATE108776 T1 AT E108776T1 AT 90917103 T AT90917103 T AT 90917103T AT 90917103 T AT90917103 T AT 90917103T AT E108776 T1 ATE108776 T1 AT E108776T1
Authority
AT
Austria
Prior art keywords
alkyl
pct
independently
receptor antagonists
date jun
Prior art date
Application number
AT90917103T
Other languages
English (en)
Inventor
Alexander Roderick Mackenzie
Peter Edward Cross
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE108776T1 publication Critical patent/ATE108776T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/86Oxygen atoms
    • C07D211/88Oxygen atoms attached in positions 2 and 6, e.g. glutarimide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT90917103T 1989-12-12 1990-11-28 Muscarin-rezeptor-antagonisten. ATE108776T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898928043A GB8928043D0 (en) 1989-12-12 1989-12-12 Muscarinic receptor antagonists

Publications (1)

Publication Number Publication Date
ATE108776T1 true ATE108776T1 (de) 1994-08-15

Family

ID=10667814

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90917103T ATE108776T1 (de) 1989-12-12 1990-11-28 Muscarin-rezeptor-antagonisten.

Country Status (13)

Country Link
US (1) US5300516A (de)
EP (1) EP0505379B1 (de)
JP (1) JPH0686428B2 (de)
AT (1) ATE108776T1 (de)
CA (1) CA2067759C (de)
DE (1) DE69010917T2 (de)
DK (1) DK0505379T3 (de)
ES (1) ES2057601T3 (de)
FI (1) FI96024C (de)
GB (1) GB8928043D0 (de)
IE (1) IE63421B1 (de)
PT (1) PT96142B (de)
WO (1) WO1991009014A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9602516D0 (en) * 1996-02-08 1996-04-10 Chiroscience Ltd Racemisation
DE10002509A1 (de) * 2000-01-21 2001-07-26 Gruenenthal Gmbh Substituierte Glutarimide
MX2018007152A (es) * 2015-12-14 2018-08-15 Ironwood Pharmaceuticals Inc Uso de estimuladores de guanilato ciclasa soluble (sgc) para el tratamiento de la disfuncion del esfinter gastrointestinal.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2664424A (en) * 1953-12-29 Dioxo-piperidines
US2848455A (en) * 1955-07-18 1958-08-19 Ciba Pharm Prod Inc Alpha-(p-amino-phenyl)-alpha-lower alkyl glutarimides
BE632403A (de) * 1962-05-17 1900-01-01
GB1455687A (en) * 1972-12-28 1976-11-17 Aspro Nicholas Ltd Pharmacologically active 3-phenyl-3-aminoalkyl-2,6-dioxo-hydro genated pyridines
GB8716338D0 (en) * 1987-07-10 1987-08-19 Nat Res Dev Anti-anxiogenic compositions

Also Published As

Publication number Publication date
FI922342A (fi) 1992-05-22
CA2067759A1 (en) 1991-06-13
IE904461A1 (en) 1991-06-19
PT96142A (pt) 1991-09-30
FI922342A0 (fi) 1992-05-22
ES2057601T3 (es) 1994-10-16
DE69010917D1 (de) 1994-08-25
GB8928043D0 (en) 1990-02-14
EP0505379A1 (de) 1992-09-30
IE63421B1 (en) 1995-04-19
EP0505379B1 (de) 1994-07-20
US5300516A (en) 1994-04-05
JPH0686428B2 (ja) 1994-11-02
PT96142B (pt) 1997-05-28
FI96024C (fi) 1996-04-25
WO1991009014A1 (en) 1991-06-27
DK0505379T3 (da) 1994-09-12
DE69010917T2 (de) 1994-11-03
JPH04505926A (ja) 1992-10-15
FI96024B (fi) 1996-01-15
CA2067759C (en) 1996-09-10

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Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee