PT95566A - Metodo para a utilizacao de derivados de 2-oxindole substituidos na posicao 3 como inibidores da biossintese de interleuquina-1 - Google Patents
Metodo para a utilizacao de derivados de 2-oxindole substituidos na posicao 3 como inibidores da biossintese de interleuquina-1Info
- Publication number
- PT95566A PT95566A PT95566A PT9556690A PT95566A PT 95566 A PT95566 A PT 95566A PT 95566 A PT95566 A PT 95566A PT 9556690 A PT9556690 A PT 9556690A PT 95566 A PT95566 A PT 95566A
- Authority
- PT
- Portugal
- Prior art keywords
- interleuquin
- biosafety
- inhibitors
- oxindole derivatives
- derivatives substituted
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US42144589A | 1989-10-13 | 1989-10-13 | |
US52905090A | 1990-05-25 | 1990-05-25 |
Publications (2)
Publication Number | Publication Date |
---|---|
PT95566A true PT95566A (pt) | 1991-08-14 |
PT95566B PT95566B (pt) | 1997-11-28 |
Family
ID=27025248
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT95566A PT95566B (pt) | 1989-10-13 | 1990-10-11 | Metodo para a utilizacao de derivados de 2-oxindole substituidos na posicao 3 como inibidores da biossintese de interleuquina-1 |
Country Status (14)
Country | Link |
---|---|
US (1) | US5192790A (pt) |
EP (1) | EP0425109B1 (pt) |
JP (1) | JPH0684300B2 (pt) |
KR (1) | KR910007526A (pt) |
AT (1) | ATE109349T1 (pt) |
AU (1) | AU624739B2 (pt) |
CA (1) | CA2027394C (pt) |
DE (1) | DE69011272T2 (pt) |
DK (1) | DK0425109T3 (pt) |
HU (2) | HUT59004A (pt) |
IE (1) | IE63140B1 (pt) |
IL (1) | IL95880A (pt) |
MY (1) | MY106834A (pt) |
PT (1) | PT95566B (pt) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6266485B1 (en) | 1998-02-19 | 2001-07-24 | Emerson Electric Co. | One-piece plastic tank and temperature control system for a hot water dispenser |
WO2000018747A1 (en) * | 1998-09-30 | 2000-04-06 | Roche Diagnostics Gmbh | Rhodanine carboxylic acid derivatives for the treatment and prevention of metabolic bone disorders |
US20020077276A1 (en) * | 1999-04-27 | 2002-06-20 | Fredeking Terry M. | Compositions and methods for treating hemorrhagic virus infections and other disorders |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4556672A (en) * | 1984-03-19 | 1985-12-03 | Pfizer Inc. | 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents |
IN162090B (pt) * | 1984-03-19 | 1988-03-26 | Pfizer | |
US4569942A (en) * | 1984-05-04 | 1986-02-11 | Pfizer Inc. | N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents |
IN161509B (pt) * | 1984-05-04 | 1987-12-19 | Pfizer | |
US4678802A (en) * | 1985-07-09 | 1987-07-07 | Pfizer Inc. | 1-acylcarbamoyloxindole-3-carboxamides as antiinflammatory agents |
GB8517958D0 (en) * | 1985-07-16 | 1985-08-21 | Cellena Cell Eng Ag | Compositions containing melatonin/homologues |
JPH01501705A (ja) * | 1986-01-30 | 1989-06-15 | ユニバ−シテイ・オブ・ユタ | 骨損失の治療 |
US4677132A (en) * | 1986-03-12 | 1987-06-30 | American Home Products Corporation | Inhibition of bone resorption by etodolac |
US4861794A (en) * | 1988-04-13 | 1989-08-29 | Pfizer Inc. | 3-substituted-2-oxindole-1-carboxamides as inhibitors of interleukin-1 biosynthesis |
US5047554A (en) * | 1989-04-18 | 1991-09-10 | Pfizer Inc. | 3-substituted-2-oxindole derivatives |
-
1990
- 1990-10-02 IL IL9588090A patent/IL95880A/en not_active IP Right Cessation
- 1990-10-03 DE DE69011272T patent/DE69011272T2/de not_active Expired - Fee Related
- 1990-10-03 AT AT90310806T patent/ATE109349T1/de not_active IP Right Cessation
- 1990-10-03 DK DK90310806.6T patent/DK0425109T3/da active
- 1990-10-03 EP EP90310806A patent/EP0425109B1/en not_active Expired - Lifetime
- 1990-10-11 MY MYPI90001771A patent/MY106834A/en unknown
- 1990-10-11 CA CA002027394A patent/CA2027394C/en not_active Expired - Fee Related
- 1990-10-11 PT PT95566A patent/PT95566B/pt not_active IP Right Cessation
- 1990-10-11 JP JP2273150A patent/JPH0684300B2/ja not_active Expired - Lifetime
- 1990-10-12 HU HU906436A patent/HUT59004A/hu unknown
- 1990-10-12 KR KR1019900016153A patent/KR910007526A/ko not_active Application Discontinuation
- 1990-10-12 AU AU64582/90A patent/AU624739B2/en not_active Ceased
- 1990-10-12 IE IE364890A patent/IE63140B1/en not_active IP Right Cessation
-
1991
- 1991-12-17 US US07/808,491 patent/US5192790A/en not_active Expired - Fee Related
-
1995
- 1995-05-11 HU HU95P/P00128P patent/HU210902A9/hu unknown
Also Published As
Publication number | Publication date |
---|---|
IL95880A (en) | 1995-12-31 |
DE69011272T2 (de) | 1994-11-24 |
EP0425109B1 (en) | 1994-08-03 |
EP0425109A3 (en) | 1992-01-15 |
AU6458290A (en) | 1991-04-18 |
MY106834A (en) | 1995-07-31 |
IE903648A1 (en) | 1991-04-24 |
HU210902A9 (en) | 1995-09-28 |
ATE109349T1 (de) | 1994-08-15 |
DE69011272D1 (de) | 1994-09-08 |
DK0425109T3 (da) | 1994-11-21 |
AU624739B2 (en) | 1992-06-18 |
HUT59004A (en) | 1992-04-28 |
US5192790A (en) | 1993-03-09 |
CA2027394A1 (en) | 1991-04-14 |
IE63140B1 (en) | 1995-03-22 |
HU906436D0 (en) | 1991-04-29 |
CA2027394C (en) | 1995-01-03 |
JPH03133929A (ja) | 1991-06-07 |
KR910007526A (ko) | 1991-05-30 |
EP0425109A2 (en) | 1991-05-02 |
PT95566B (pt) | 1997-11-28 |
JPH0684300B2 (ja) | 1994-10-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB1A | Laying open of patent application |
Effective date: 19910320 |
|
FG3A | Patent granted, date of granting |
Effective date: 19970829 |
|
MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20010228 |