PT95566A - Metodo para a utilizacao de derivados de 2-oxindole substituidos na posicao 3 como inibidores da biossintese de interleuquina-1 - Google Patents

Metodo para a utilizacao de derivados de 2-oxindole substituidos na posicao 3 como inibidores da biossintese de interleuquina-1

Info

Publication number
PT95566A
PT95566A PT95566A PT9556690A PT95566A PT 95566 A PT95566 A PT 95566A PT 95566 A PT95566 A PT 95566A PT 9556690 A PT9556690 A PT 9556690A PT 95566 A PT95566 A PT 95566A
Authority
PT
Portugal
Prior art keywords
interleuquin
biosafety
inhibitors
oxindole derivatives
derivatives substituted
Prior art date
Application number
PT95566A
Other languages
English (en)
Other versions
PT95566B (pt
Inventor
Gary Richard Schulte
Carl Joseph Goddard
Douglas Charles Hanson
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PT95566A publication Critical patent/PT95566A/pt
Publication of PT95566B publication Critical patent/PT95566B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT95566A 1989-10-13 1990-10-11 Metodo para a utilizacao de derivados de 2-oxindole substituidos na posicao 3 como inibidores da biossintese de interleuquina-1 PT95566B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42144589A 1989-10-13 1989-10-13
US52905090A 1990-05-25 1990-05-25

Publications (2)

Publication Number Publication Date
PT95566A true PT95566A (pt) 1991-08-14
PT95566B PT95566B (pt) 1997-11-28

Family

ID=27025248

Family Applications (1)

Application Number Title Priority Date Filing Date
PT95566A PT95566B (pt) 1989-10-13 1990-10-11 Metodo para a utilizacao de derivados de 2-oxindole substituidos na posicao 3 como inibidores da biossintese de interleuquina-1

Country Status (14)

Country Link
US (1) US5192790A (pt)
EP (1) EP0425109B1 (pt)
JP (1) JPH0684300B2 (pt)
KR (1) KR910007526A (pt)
AT (1) ATE109349T1 (pt)
AU (1) AU624739B2 (pt)
CA (1) CA2027394C (pt)
DE (1) DE69011272T2 (pt)
DK (1) DK0425109T3 (pt)
HU (2) HUT59004A (pt)
IE (1) IE63140B1 (pt)
IL (1) IL95880A (pt)
MY (1) MY106834A (pt)
PT (1) PT95566B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6266485B1 (en) 1998-02-19 2001-07-24 Emerson Electric Co. One-piece plastic tank and temperature control system for a hot water dispenser
WO2000018747A1 (en) * 1998-09-30 2000-04-06 Roche Diagnostics Gmbh Rhodanine carboxylic acid derivatives for the treatment and prevention of metabolic bone disorders
US20020077276A1 (en) * 1999-04-27 2002-06-20 Fredeking Terry M. Compositions and methods for treating hemorrhagic virus infections and other disorders

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4556672A (en) * 1984-03-19 1985-12-03 Pfizer Inc. 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents
IN162090B (pt) * 1984-03-19 1988-03-26 Pfizer
US4569942A (en) * 1984-05-04 1986-02-11 Pfizer Inc. N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents
IN161509B (pt) * 1984-05-04 1987-12-19 Pfizer
US4678802A (en) * 1985-07-09 1987-07-07 Pfizer Inc. 1-acylcarbamoyloxindole-3-carboxamides as antiinflammatory agents
GB8517958D0 (en) * 1985-07-16 1985-08-21 Cellena Cell Eng Ag Compositions containing melatonin/homologues
JPH01501705A (ja) * 1986-01-30 1989-06-15 ユニバ−シテイ・オブ・ユタ 骨損失の治療
US4677132A (en) * 1986-03-12 1987-06-30 American Home Products Corporation Inhibition of bone resorption by etodolac
US4861794A (en) * 1988-04-13 1989-08-29 Pfizer Inc. 3-substituted-2-oxindole-1-carboxamides as inhibitors of interleukin-1 biosynthesis
US5047554A (en) * 1989-04-18 1991-09-10 Pfizer Inc. 3-substituted-2-oxindole derivatives

Also Published As

Publication number Publication date
IL95880A (en) 1995-12-31
DE69011272T2 (de) 1994-11-24
EP0425109B1 (en) 1994-08-03
EP0425109A3 (en) 1992-01-15
AU6458290A (en) 1991-04-18
MY106834A (en) 1995-07-31
IE903648A1 (en) 1991-04-24
HU210902A9 (en) 1995-09-28
ATE109349T1 (de) 1994-08-15
DE69011272D1 (de) 1994-09-08
DK0425109T3 (da) 1994-11-21
AU624739B2 (en) 1992-06-18
HUT59004A (en) 1992-04-28
US5192790A (en) 1993-03-09
CA2027394A1 (en) 1991-04-14
IE63140B1 (en) 1995-03-22
HU906436D0 (en) 1991-04-29
CA2027394C (en) 1995-01-03
JPH03133929A (ja) 1991-06-07
KR910007526A (ko) 1991-05-30
EP0425109A2 (en) 1991-05-02
PT95566B (pt) 1997-11-28
JPH0684300B2 (ja) 1994-10-26

Similar Documents

Publication Publication Date Title
SE9803710D0 (sv) Use of certain drugs for treating nerve root injury
IT1212896B (it) Metodo di somministrazione per via inalatoria di gangliosidi e derivati, e composizioni farmaceutiche relative
DE58902712D1 (de) N-acetylglucosamin-zubereitungen zur buccalen anwendung.
PT90248A (pt) Metodo para a utilizacao de 2-oxindole-1-carboxamidas 3-substituidas como inibidores da biossintese da interleucina-1
IL111580A (en) Use of melatonin derivatives in the preparation of pharmaceutical compositions for use in treating sleep disorders
PT95566A (pt) Metodo para a utilizacao de derivados de 2-oxindole substituidos na posicao 3 como inibidores da biossintese de interleuquina-1
IL111579A (en) Use of melatonin derivatives in the preparation of pharmaceutical compositions for use in treating desynchronization disorders
GB2204488B (en) Pharmaceutical compositions for the treatment or prophylaxis of skin disorders
ES2192018T3 (es) Composicion farmaceutica que contiene estimuladores de interferon-gamma.
ES2081884T3 (es) Factor citotoxico oligodendrocitico.
ATE242766T1 (de) Neue derivate von benzoylalkyl-1,2,3,6- tetrahydropyridinen
IT8920006A0 (it) Composizioni farmaceutiche comprendenti derivati del glicerolo 3 fosfato atte al trattamento di patologie del sistema nervoso

Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19910320

FG3A Patent granted, date of granting

Effective date: 19970829

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20010228