PT927217E - Compostos inibidores angiogenicos - Google Patents

Compostos inibidores angiogenicos

Info

Publication number
PT927217E
PT927217E PT97929038T PT97929038T PT927217E PT 927217 E PT927217 E PT 927217E PT 97929038 T PT97929038 T PT 97929038T PT 97929038 T PT97929038 T PT 97929038T PT 927217 E PT927217 E PT 927217E
Authority
PT
Portugal
Prior art keywords
inhibitor compounds
angiogenic inhibitor
dendrimer
anionic
cationic
Prior art date
Application number
PT97929038T
Other languages
English (en)
Portuguese (pt)
Inventor
Matthews Barry Ross
Holan George
Original Assignee
Starpharma Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Starpharma Pty Ltd filed Critical Starpharma Pty Ltd
Publication of PT927217E publication Critical patent/PT927217E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/36Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino acids, polyamines and polycarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G83/00Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
    • C08G83/002Dendritic macromolecules
    • C08G83/003Dendrimers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/795Polymers containing sulfur
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/08Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
    • C08G69/10Alpha-amino-carboxylic acids
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/16Dendrimers and dendritic polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Polymers & Plastics (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Optical Fibers, Optical Fiber Cores, And Optical Fiber Bundles (AREA)
  • Liquid Crystal Substances (AREA)
  • Chemical And Physical Treatments For Wood And The Like (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Polyamides (AREA)
PT97929038T 1996-07-17 1997-07-17 Compostos inibidores angiogenicos PT927217E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPO1044A AUPO104496A0 (en) 1996-07-17 1996-07-17 Angiogenic inhibitory compounds

Publications (1)

Publication Number Publication Date
PT927217E true PT927217E (pt) 2006-08-31

Family

ID=3795360

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97929038T PT927217E (pt) 1996-07-17 1997-07-17 Compostos inibidores angiogenicos

Country Status (15)

Country Link
US (1) US6426067B1 (zh)
EP (1) EP0927217B1 (zh)
JP (1) JP2000516211A (zh)
KR (1) KR100564714B1 (zh)
CN (1) CN1161128C (zh)
AT (1) ATE325154T1 (zh)
AU (1) AUPO104496A0 (zh)
BR (1) BR9710375A (zh)
CA (1) CA2262862C (zh)
DE (1) DE69735810T2 (zh)
DK (1) DK0927217T3 (zh)
ES (1) ES2260796T3 (zh)
NZ (1) NZ333488A (zh)
PT (1) PT927217E (zh)
WO (1) WO1998003573A1 (zh)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7018637B2 (en) * 1998-02-23 2006-03-28 Aventis Pasteur, Inc Multi-oligosaccharide glycoconjugate bacterial meningitis vaccines
FR2781485B1 (fr) 1998-07-21 2003-08-08 Denis Barritault Polymeres biocompatibles leur procede de preparation et les compositions les contenant
AUPP584298A0 (en) * 1998-09-14 1998-10-08 Starpharma Limited Antimicrobial and antiparasitic agents
GB0001481D0 (en) * 2000-01-21 2000-03-15 Theryte Ltd System for delivering a medicament
JP2003528140A (ja) * 2000-03-27 2003-09-24 ザ・スクリプス・リサーチ・インステイチユート 血管形成と腫瘍成長を阻害する方法
KR100413532B1 (ko) * 2001-02-14 2003-12-31 학교법인 포항공과대학교 폴리아민이 말단에 치환된 덴드리머 및 그 제조방법
AUPR412901A0 (en) * 2001-03-30 2001-05-03 Starpharma Limited Agents for the prevention and treatment of sexually transmitted disease s - II
AUPR412801A0 (en) * 2001-03-30 2001-05-03 Starpharma Limited Agent for the prevention and treatment of sexually transmitted disease s - I
US20030135195A1 (en) * 2002-01-16 2003-07-17 Oscar Jimenez Highly lubricious hydrophilic coating utilizing dendrimers
US20030180250A1 (en) * 2002-03-22 2003-09-25 Council Of Scientific And Industrial Research Compositions and complexes containing a macromolecular compound as potential anti-inflammatory agents
EP1617808A4 (en) * 2003-04-25 2011-11-02 Penn State Res Found METHOD AND SYSTEM FOR THE SYSTEMIC DISTRIBUTION OF GROWTH-INHIBITORS OF LIPID-DERIVED BIOACTIVE COMPOUNDS
EP2380872B1 (en) * 2004-06-15 2014-04-23 Cellceutix Corporation Polycationic compounds and uses thereof
FR2876916B1 (fr) * 2004-10-25 2007-01-05 Midi Pyrenees Incubateur Produit implantable de surface fonctionnalisee au moyen de dendrimeres a terminaisons anioniques
KR100667171B1 (ko) 2005-05-10 2007-01-12 서애희 세포내 물질전달용 pamam 유도체 및 이를 이용한세포내 원하는 물질의 전달방법
GR1005807B (el) * 2005-07-13 2008-02-06 Αρισταρχος Παπαγιανναρος Ρυθμιστικο λιποσωμιακο συστημα ελεγχομενης αποδεσμευσης: νεα φαρμακοτεχνικη μορφη για εγκλωβισμο αντικαρκινικων φαρμακων με βαση την τεχνολογια των λιποσωματων και των δενδριμερων
WO2007045010A1 (en) * 2005-10-21 2007-04-26 Starpharma Pty Limited Inhibitory compounds
DE102005056592A1 (de) 2005-11-25 2007-05-31 Basf Ag Herstellung und Verwendung von hochfunktionellen, hoch-oder hyperverzweigten Polylysinen
CA2636599C (en) * 2006-01-20 2014-07-15 Starpharma Pty Limited Modified macromolecule
CN101405010B (zh) 2006-03-22 2013-03-06 星药股份有限公司 避孕组合物
DE102006036326A1 (de) * 2006-08-03 2008-02-07 Charité - Universitätsmedizin Berlin Dendritische Polyglycerolsulfate und -sulfonate und deren Verwendung bei entzündlichen Erkrankungen
WO2008157372A2 (en) 2007-06-14 2008-12-24 Massachusetts Institute Of Technology Self assembled films for protein and drug delivery applications
US8658148B2 (en) 2007-06-22 2014-02-25 Genzyme Corporation Chemically modified dendrimers
US10106565B2 (en) 2008-08-01 2018-10-23 Centre National De La Recherche Scientifique Phosphorylated dendrimers as antiinflammatory drugs
WO2010013086A1 (en) * 2008-08-01 2010-02-04 Centre National De La Recherche Scientifique Phosphorylated dendrimers as antiinflammatory drugs
US9198875B2 (en) 2008-08-17 2015-12-01 Massachusetts Institute Of Technology Controlled delivery of bioactive agents from decomposable films
KR20180126621A (ko) * 2011-05-16 2018-11-27 스타파마 피티와이 리미티드 세균성 질염의 치료 또는 예방 방법
US10278927B2 (en) 2012-04-23 2019-05-07 Massachusetts Institute Of Technology Stable layer-by-layer coated particles
WO2014134029A1 (en) 2013-02-26 2014-09-04 Massachusetts Institute Of Technology Nucleic acid particles, methods and use thereof
US9463244B2 (en) 2013-03-15 2016-10-11 Massachusetts Institute Of Technology Compositions and methods for nucleic acid delivery
TWI586369B (zh) * 2015-01-26 2017-06-11 國立交通大學 樹狀化合物、具有功能性基團的樹狀化合物以及抗體
DE102017002810A1 (de) 2017-03-22 2018-09-27 Reinhard Brossmer Sialinsäurederivate mit C-C Dreifachbindung und deren Herstellung
US11419947B2 (en) 2017-10-30 2022-08-23 Massachusetts Institute Of Technology Layer-by-layer nanoparticles for cytokine therapy in cancer treatment
WO2021002984A1 (en) 2019-05-30 2021-01-07 Massachusetts Institute Of Technology Peptide nucleic acid functionalized hydrogel microneedles for sampling and detection of interstitial fluid nucleic acids

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2182667B1 (zh) * 1972-05-03 1978-03-03 Rhone Poulenc Ind
US4289872A (en) * 1979-04-06 1981-09-15 Allied Corporation Macromolecular highly branched homogeneous compound based on lysine units
US4410688A (en) 1981-04-29 1983-10-18 Allied Corporation Macromolecular highly branched homogeneous compound
HU187669B (en) * 1982-03-31 1986-02-28 Richter Gedeon Vegyeszet Process for producing new copolymeres and salts
US4507466A (en) 1983-01-07 1985-03-26 The Dow Chemical Corporation Dense star polymers having core, core branches, terminal groups
US4558120A (en) 1983-01-07 1985-12-10 The Dow Chemical Company Dense star polymer
US4568737A (en) 1983-01-07 1986-02-04 The Dow Chemical Company Dense star polymers and dendrimers
US4587329A (en) 1984-08-17 1986-05-06 The Dow Chemical Company Dense star polymers having two dimensional molecular diameter
NL8900442A (nl) * 1989-02-22 1990-09-17 Stichting Rega V Z W Gesulfateerde vinylpolymeren in geneesmiddelen voor het behandelen van retrovirus-infecties.
JP2909500B2 (ja) * 1989-03-23 1999-06-23 ベルレックス、ラボラトリーズ、レンコーポレイテッド 水溶性抗高脂質血症剤として有用な官能化側鎖を有するポリアミド
FR2669535A1 (fr) * 1990-11-26 1992-05-29 Medgenix Group Sa Utilisation a titre de medicament de macromolecules polysulfonees.
GB2260134A (en) * 1991-10-04 1993-04-07 Erba Carlo Spa Derivatives of poly-5-amino-3-carboxy-1-methyl compounds
ATE183924T1 (de) * 1992-01-14 1999-09-15 Hisamitsu Pharmaceutical Co Cholesterinspiegelsenkendes mittel
HUT72993A (en) * 1992-08-19 1996-06-28 Merrell Dow Pharma Process to prepare phatmaceutical compns. contg antiangiogenic oligomers
US5460807A (en) * 1992-08-19 1995-10-24 Merrell Dow Pharmaceuticals Inc. Antiproliferative oligomers
IL108951A0 (en) * 1994-03-13 1994-06-24 Hadasit Med Res Service Pharmaceutical compositions containing polysulfated polysaccharides
JPH07267879A (ja) 1994-03-30 1995-10-17 Unitika Ltd 血管新生阻害剤
AUPM623994A0 (en) 1994-06-15 1994-07-07 Biomolecular Research Institute Limited Antiviral dendrimers

Also Published As

Publication number Publication date
JP2000516211A (ja) 2000-12-05
CA2262862C (en) 2005-10-04
ES2260796T3 (es) 2006-11-01
WO1998003573A1 (en) 1998-01-29
EP0927217A4 (en) 2003-04-23
CN1161128C (zh) 2004-08-11
CA2262862A1 (en) 1998-01-29
US6426067B1 (en) 2002-07-30
EP0927217A1 (en) 1999-07-07
AU3330297A (en) 1998-02-10
KR100564714B1 (ko) 2006-03-28
EP0927217B1 (en) 2006-05-03
NZ333488A (en) 2000-07-28
BR9710375A (pt) 1999-08-17
AUPO104496A0 (en) 1996-08-08
ATE325154T1 (de) 2006-06-15
DE69735810D1 (de) 2006-06-08
AU715761B2 (en) 2000-02-10
DK0927217T3 (da) 2006-08-14
DE69735810T2 (de) 2006-12-21
KR20000067876A (ko) 2000-11-25
CN1225654A (zh) 1999-08-11

Similar Documents

Publication Publication Date Title
PT927217E (pt) Compostos inibidores angiogenicos
ATE312866T1 (de) Antivirale dendrimere
EA200100529A1 (ru) Нестероидные ингибиторы воспалений
ATE268806T1 (de) Lichtemittierende dendrimere
CO5160265A1 (es) Esteres aminoacidos de ribavirina y composiciones farmaceuticas que los contienen .
NO964976D0 (no) Kopolymer-1-forbedringer kopolymerpreparater
PT925319E (pt) Polimeros de triazina e sua utilizacao em dispositivos electroluminescentes
EE9900481A (et) Väikesed molekulid, mida kasutatakse põletikuliste haiguste raviks
TR199800773T2 (xx) Trombin inhibit�rleri.
NO934218L (no) Inhibitorer av cathepsin g og elastase for forhindring av bindevevsned-brytning
NZ333541A (en) Antiviral polyionic linear polymers for treatment of HIV, RSV, influenza, hepatitis and other enveloped viruses
ATE235462T1 (de) Metalloproteinase-inhibitoren
NO924045L (no) Anti-inflammatoriske hydroksamsyrer og n-hydroksyurinstoffer
DE68903092D1 (de) Laktamimide in der behandlung arzneiresistenter protozoeninjektionen.
ATE231131T1 (de) Verbindungen mit wachtumshormon freisetzenden eigenschaften
EA199800200A1 (ru) Ингибиторы пролилэндопептидазы
IS6130A (is) Bólgueyðandi meðhöndlun fyrir bólgu tengt smit
FR2599752B1 (fr) Variants de l'alpha1- antitrypsine utiles notamment comme inhibiteurs de la kallikreine
NO20013924L (no) Sammensetninger og metoder for å kontrollere stickies
NO924361L (no) Formazan parasittiske midler
EA199900174A1 (ru) Способ лечения биполярного расстройства
MX9204528A (es) 0etodo para tratar el sindrome premenstrual mediante administracion de un inhibidor de la enzima de conversion de angiotensina.
ES2097274T3 (es) Composiciones polimericas autoextinguibles.
MX9801792A (es) Inhibidores cicloantihelminticos.
BR9901387A (pt) Composições para a cura de polìmero.