PT927217E - Compostos inibidores angiogenicos - Google Patents
Compostos inibidores angiogenicosInfo
- Publication number
- PT927217E PT927217E PT97929038T PT97929038T PT927217E PT 927217 E PT927217 E PT 927217E PT 97929038 T PT97929038 T PT 97929038T PT 97929038 T PT97929038 T PT 97929038T PT 927217 E PT927217 E PT 927217E
- Authority
- PT
- Portugal
- Prior art keywords
- inhibitor compounds
- angiogenic inhibitor
- dendrimer
- anionic
- cationic
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 230000002491 angiogenic effect Effects 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 125000002091 cationic group Chemical group 0.000 abstract 2
- 239000000412 dendrimer Substances 0.000 abstract 2
- 229920000736 dendritic polymer Polymers 0.000 abstract 2
- 229920001282 polysaccharide Polymers 0.000 abstract 2
- 230000033115 angiogenesis Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
- C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
- C08G69/36—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino acids, polyamines and polycarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
- C08G83/002—Dendritic macromolecules
- C08G83/003—Dendrimers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/795—Polymers containing sulfur
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
- C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
- C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
- C08G69/10—Alpha-amino-carboxylic acids
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/16—Dendrimers and dendritic polymers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Polymers & Plastics (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Optical Fibers, Optical Fiber Cores, And Optical Fiber Bundles (AREA)
- Liquid Crystal Substances (AREA)
- Chemical And Physical Treatments For Wood And The Like (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Polyamides (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPO1044A AUPO104496A0 (en) | 1996-07-17 | 1996-07-17 | Angiogenic inhibitory compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
PT927217E true PT927217E (pt) | 2006-08-31 |
Family
ID=3795360
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT97929038T PT927217E (pt) | 1996-07-17 | 1997-07-17 | Compostos inibidores angiogenicos |
Country Status (15)
Country | Link |
---|---|
US (1) | US6426067B1 (zh) |
EP (1) | EP0927217B1 (zh) |
JP (1) | JP2000516211A (zh) |
KR (1) | KR100564714B1 (zh) |
CN (1) | CN1161128C (zh) |
AT (1) | ATE325154T1 (zh) |
AU (1) | AUPO104496A0 (zh) |
BR (1) | BR9710375A (zh) |
CA (1) | CA2262862C (zh) |
DE (1) | DE69735810T2 (zh) |
DK (1) | DK0927217T3 (zh) |
ES (1) | ES2260796T3 (zh) |
NZ (1) | NZ333488A (zh) |
PT (1) | PT927217E (zh) |
WO (1) | WO1998003573A1 (zh) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7018637B2 (en) * | 1998-02-23 | 2006-03-28 | Aventis Pasteur, Inc | Multi-oligosaccharide glycoconjugate bacterial meningitis vaccines |
FR2781485B1 (fr) | 1998-07-21 | 2003-08-08 | Denis Barritault | Polymeres biocompatibles leur procede de preparation et les compositions les contenant |
AUPP584298A0 (en) * | 1998-09-14 | 1998-10-08 | Starpharma Limited | Antimicrobial and antiparasitic agents |
GB0001481D0 (en) * | 2000-01-21 | 2000-03-15 | Theryte Ltd | System for delivering a medicament |
JP2003528140A (ja) * | 2000-03-27 | 2003-09-24 | ザ・スクリプス・リサーチ・インステイチユート | 血管形成と腫瘍成長を阻害する方法 |
KR100413532B1 (ko) * | 2001-02-14 | 2003-12-31 | 학교법인 포항공과대학교 | 폴리아민이 말단에 치환된 덴드리머 및 그 제조방법 |
AUPR412901A0 (en) * | 2001-03-30 | 2001-05-03 | Starpharma Limited | Agents for the prevention and treatment of sexually transmitted disease s - II |
AUPR412801A0 (en) * | 2001-03-30 | 2001-05-03 | Starpharma Limited | Agent for the prevention and treatment of sexually transmitted disease s - I |
US20030135195A1 (en) * | 2002-01-16 | 2003-07-17 | Oscar Jimenez | Highly lubricious hydrophilic coating utilizing dendrimers |
US20030180250A1 (en) * | 2002-03-22 | 2003-09-25 | Council Of Scientific And Industrial Research | Compositions and complexes containing a macromolecular compound as potential anti-inflammatory agents |
EP1617808A4 (en) * | 2003-04-25 | 2011-11-02 | Penn State Res Found | METHOD AND SYSTEM FOR THE SYSTEMIC DISTRIBUTION OF GROWTH-INHIBITORS OF LIPID-DERIVED BIOACTIVE COMPOUNDS |
EP2380872B1 (en) * | 2004-06-15 | 2014-04-23 | Cellceutix Corporation | Polycationic compounds and uses thereof |
FR2876916B1 (fr) * | 2004-10-25 | 2007-01-05 | Midi Pyrenees Incubateur | Produit implantable de surface fonctionnalisee au moyen de dendrimeres a terminaisons anioniques |
KR100667171B1 (ko) | 2005-05-10 | 2007-01-12 | 서애희 | 세포내 물질전달용 pamam 유도체 및 이를 이용한세포내 원하는 물질의 전달방법 |
GR1005807B (el) * | 2005-07-13 | 2008-02-06 | Αρισταρχος Παπαγιανναρος | Ρυθμιστικο λιποσωμιακο συστημα ελεγχομενης αποδεσμευσης: νεα φαρμακοτεχνικη μορφη για εγκλωβισμο αντικαρκινικων φαρμακων με βαση την τεχνολογια των λιποσωματων και των δενδριμερων |
WO2007045010A1 (en) * | 2005-10-21 | 2007-04-26 | Starpharma Pty Limited | Inhibitory compounds |
DE102005056592A1 (de) | 2005-11-25 | 2007-05-31 | Basf Ag | Herstellung und Verwendung von hochfunktionellen, hoch-oder hyperverzweigten Polylysinen |
CA2636599C (en) * | 2006-01-20 | 2014-07-15 | Starpharma Pty Limited | Modified macromolecule |
CN101405010B (zh) | 2006-03-22 | 2013-03-06 | 星药股份有限公司 | 避孕组合物 |
DE102006036326A1 (de) * | 2006-08-03 | 2008-02-07 | Charité - Universitätsmedizin Berlin | Dendritische Polyglycerolsulfate und -sulfonate und deren Verwendung bei entzündlichen Erkrankungen |
WO2008157372A2 (en) | 2007-06-14 | 2008-12-24 | Massachusetts Institute Of Technology | Self assembled films for protein and drug delivery applications |
US8658148B2 (en) | 2007-06-22 | 2014-02-25 | Genzyme Corporation | Chemically modified dendrimers |
US10106565B2 (en) | 2008-08-01 | 2018-10-23 | Centre National De La Recherche Scientifique | Phosphorylated dendrimers as antiinflammatory drugs |
WO2010013086A1 (en) * | 2008-08-01 | 2010-02-04 | Centre National De La Recherche Scientifique | Phosphorylated dendrimers as antiinflammatory drugs |
US9198875B2 (en) | 2008-08-17 | 2015-12-01 | Massachusetts Institute Of Technology | Controlled delivery of bioactive agents from decomposable films |
KR20180126621A (ko) * | 2011-05-16 | 2018-11-27 | 스타파마 피티와이 리미티드 | 세균성 질염의 치료 또는 예방 방법 |
US10278927B2 (en) | 2012-04-23 | 2019-05-07 | Massachusetts Institute Of Technology | Stable layer-by-layer coated particles |
WO2014134029A1 (en) | 2013-02-26 | 2014-09-04 | Massachusetts Institute Of Technology | Nucleic acid particles, methods and use thereof |
US9463244B2 (en) | 2013-03-15 | 2016-10-11 | Massachusetts Institute Of Technology | Compositions and methods for nucleic acid delivery |
TWI586369B (zh) * | 2015-01-26 | 2017-06-11 | 國立交通大學 | 樹狀化合物、具有功能性基團的樹狀化合物以及抗體 |
DE102017002810A1 (de) | 2017-03-22 | 2018-09-27 | Reinhard Brossmer | Sialinsäurederivate mit C-C Dreifachbindung und deren Herstellung |
US11419947B2 (en) | 2017-10-30 | 2022-08-23 | Massachusetts Institute Of Technology | Layer-by-layer nanoparticles for cytokine therapy in cancer treatment |
WO2021002984A1 (en) | 2019-05-30 | 2021-01-07 | Massachusetts Institute Of Technology | Peptide nucleic acid functionalized hydrogel microneedles for sampling and detection of interstitial fluid nucleic acids |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2182667B1 (zh) * | 1972-05-03 | 1978-03-03 | Rhone Poulenc Ind | |
US4289872A (en) * | 1979-04-06 | 1981-09-15 | Allied Corporation | Macromolecular highly branched homogeneous compound based on lysine units |
US4410688A (en) | 1981-04-29 | 1983-10-18 | Allied Corporation | Macromolecular highly branched homogeneous compound |
HU187669B (en) * | 1982-03-31 | 1986-02-28 | Richter Gedeon Vegyeszet | Process for producing new copolymeres and salts |
US4507466A (en) | 1983-01-07 | 1985-03-26 | The Dow Chemical Corporation | Dense star polymers having core, core branches, terminal groups |
US4558120A (en) | 1983-01-07 | 1985-12-10 | The Dow Chemical Company | Dense star polymer |
US4568737A (en) | 1983-01-07 | 1986-02-04 | The Dow Chemical Company | Dense star polymers and dendrimers |
US4587329A (en) | 1984-08-17 | 1986-05-06 | The Dow Chemical Company | Dense star polymers having two dimensional molecular diameter |
NL8900442A (nl) * | 1989-02-22 | 1990-09-17 | Stichting Rega V Z W | Gesulfateerde vinylpolymeren in geneesmiddelen voor het behandelen van retrovirus-infecties. |
JP2909500B2 (ja) * | 1989-03-23 | 1999-06-23 | ベルレックス、ラボラトリーズ、レンコーポレイテッド | 水溶性抗高脂質血症剤として有用な官能化側鎖を有するポリアミド |
FR2669535A1 (fr) * | 1990-11-26 | 1992-05-29 | Medgenix Group Sa | Utilisation a titre de medicament de macromolecules polysulfonees. |
GB2260134A (en) * | 1991-10-04 | 1993-04-07 | Erba Carlo Spa | Derivatives of poly-5-amino-3-carboxy-1-methyl compounds |
ATE183924T1 (de) * | 1992-01-14 | 1999-09-15 | Hisamitsu Pharmaceutical Co | Cholesterinspiegelsenkendes mittel |
HUT72993A (en) * | 1992-08-19 | 1996-06-28 | Merrell Dow Pharma | Process to prepare phatmaceutical compns. contg antiangiogenic oligomers |
US5460807A (en) * | 1992-08-19 | 1995-10-24 | Merrell Dow Pharmaceuticals Inc. | Antiproliferative oligomers |
IL108951A0 (en) * | 1994-03-13 | 1994-06-24 | Hadasit Med Res Service | Pharmaceutical compositions containing polysulfated polysaccharides |
JPH07267879A (ja) | 1994-03-30 | 1995-10-17 | Unitika Ltd | 血管新生阻害剤 |
AUPM623994A0 (en) | 1994-06-15 | 1994-07-07 | Biomolecular Research Institute Limited | Antiviral dendrimers |
-
1996
- 1996-07-17 AU AUPO1044A patent/AUPO104496A0/en not_active Abandoned
-
1997
- 1997-07-17 WO PCT/AU1997/000447 patent/WO1998003573A1/en active IP Right Grant
- 1997-07-17 JP JP10506372A patent/JP2000516211A/ja not_active Ceased
- 1997-07-17 CN CNB971964521A patent/CN1161128C/zh not_active Expired - Fee Related
- 1997-07-17 US US09/230,188 patent/US6426067B1/en not_active Expired - Fee Related
- 1997-07-17 AT AT97929038T patent/ATE325154T1/de not_active IP Right Cessation
- 1997-07-17 DK DK97929038T patent/DK0927217T3/da active
- 1997-07-17 NZ NZ333488A patent/NZ333488A/xx unknown
- 1997-07-17 BR BR9710375A patent/BR9710375A/pt not_active IP Right Cessation
- 1997-07-17 CA CA002262862A patent/CA2262862C/en not_active Expired - Fee Related
- 1997-07-17 PT PT97929038T patent/PT927217E/pt unknown
- 1997-07-17 EP EP97929038A patent/EP0927217B1/en not_active Expired - Lifetime
- 1997-07-17 DE DE69735810T patent/DE69735810T2/de not_active Expired - Fee Related
- 1997-07-17 KR KR1019997000264A patent/KR100564714B1/ko not_active IP Right Cessation
- 1997-07-17 ES ES97929038T patent/ES2260796T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP2000516211A (ja) | 2000-12-05 |
CA2262862C (en) | 2005-10-04 |
ES2260796T3 (es) | 2006-11-01 |
WO1998003573A1 (en) | 1998-01-29 |
EP0927217A4 (en) | 2003-04-23 |
CN1161128C (zh) | 2004-08-11 |
CA2262862A1 (en) | 1998-01-29 |
US6426067B1 (en) | 2002-07-30 |
EP0927217A1 (en) | 1999-07-07 |
AU3330297A (en) | 1998-02-10 |
KR100564714B1 (ko) | 2006-03-28 |
EP0927217B1 (en) | 2006-05-03 |
NZ333488A (en) | 2000-07-28 |
BR9710375A (pt) | 1999-08-17 |
AUPO104496A0 (en) | 1996-08-08 |
ATE325154T1 (de) | 2006-06-15 |
DE69735810D1 (de) | 2006-06-08 |
AU715761B2 (en) | 2000-02-10 |
DK0927217T3 (da) | 2006-08-14 |
DE69735810T2 (de) | 2006-12-21 |
KR20000067876A (ko) | 2000-11-25 |
CN1225654A (zh) | 1999-08-11 |
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