PT91045A - Processo para a preparacao de derivados aminodiol n-terminais etereos de amino--acidos, uteis como agentes anti-hipertensivos - Google Patents
Processo para a preparacao de derivados aminodiol n-terminais etereos de amino--acidos, uteis como agentes anti-hipertensivosInfo
- Publication number
- PT91045A PT91045A PT91045A PT9104589A PT91045A PT 91045 A PT91045 A PT 91045A PT 91045 A PT91045 A PT 91045A PT 9104589 A PT9104589 A PT 9104589A PT 91045 A PT91045 A PT 91045A
- Authority
- PT
- Portugal
- Prior art keywords
- etereous
- uteis
- preparation
- amino acid
- hypertensive agents
- Prior art date
Links
- CIAZEFCFQFQJLB-NXEZZACHSA-N (1r,2r)-2-amino-1-(4-methylsulfonylphenyl)propane-1,3-diol Chemical class CS(=O)(=O)C1=CC=C([C@@H](O)[C@H](N)CO)C=C1 CIAZEFCFQFQJLB-NXEZZACHSA-N 0.000 title 1
- 150000001413 amino acids Chemical class 0.000 title 1
- 239000002220 antihypertensive agent Substances 0.000 title 1
- 229940030600 antihypertensive agent Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/14—Angiotensins: Related peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/16—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D233/26—Radicals substituted by carbon atoms having three bonds to hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/86—Renin inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/214,698 US4900746A (en) | 1988-07-01 | 1988-07-01 | Ethereal N-terminal aminodiol amino acid derivatives as anti-hypertensive agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT91045A true PT91045A (pt) | 1990-02-08 |
| PT91045B PT91045B (pt) | 1994-12-30 |
Family
ID=22800093
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT91022A PT91022A (pt) | 1988-07-01 | 1989-06-29 | Processo para a preparacao de derivados aminodiol n-terminais etereos de amino--acidos, uteis como agentes anti-hipertensivos |
| PT91045A PT91045B (pt) | 1988-07-01 | 1989-07-03 | Processo para a preparacao de derivados aminodiol n-terminais etereos de amino--acidos, uteis como agentes anti-hipertensivos |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT91022A PT91022A (pt) | 1988-07-01 | 1989-06-29 | Processo para a preparacao de derivados aminodiol n-terminais etereos de amino--acidos, uteis como agentes anti-hipertensivos |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4900746A (pt) |
| KR (1) | KR900001720A (pt) |
| DK (1) | DK327089A (pt) |
| NO (1) | NO892744D0 (pt) |
| PT (2) | PT91022A (pt) |
| ZA (1) | ZA895000B (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5032577A (en) * | 1986-12-31 | 1991-07-16 | Abbott Laboratories | Peptidylaminodiols |
| ATE107658T1 (de) * | 1988-01-26 | 1994-07-15 | Sankyo Co | Renin inhibierende polypeptide, ihre herstellung und anwendung. |
| US5229420A (en) * | 1988-07-01 | 1993-07-20 | G. D. Searle & Co. | Ethereal N-terminal aminodiol amino acid derivatives as anti-hypertensive agents |
| US5312838A (en) * | 1992-09-21 | 1994-05-17 | G. D. Searle & Co. | β-alanineamide aryl/alkylsulfide/sulfonyl-terminated amino-diol compounds for treatment of hypertension |
| US5432201A (en) * | 1993-11-22 | 1995-07-11 | G. D. Searle & Co. | Alkylaminoalkyl-sulfonyl-terminated β-alanineamide amino-diol compounds for treatment of hypertension |
| US6133317A (en) * | 1995-11-15 | 2000-10-17 | Hart; Francis J. | Oxalic acid or oxalate composition and method of treatment |
| US6133318A (en) | 1995-11-15 | 2000-10-17 | Hart; Francis J. | Oxalic acid or oxalate compositions and methods for bacterial, viral, and other diseases or conditions |
| WO2003043618A2 (en) * | 2001-11-19 | 2003-05-30 | Elan Pharmaceuticals, Inc. | Amino diols useful in the treatment of alzheimer's disease |
| KR102513744B1 (ko) * | 2020-06-30 | 2023-03-23 | 구선모 | 미유 및 이의 제조방법 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59227851A (ja) * | 1983-06-09 | 1984-12-21 | Sankyo Co Ltd | レニン阻害作用を有するペプチド類 |
| US4652551A (en) * | 1984-06-22 | 1987-03-24 | Abbott Laboratories | Renin inhibiting compounds |
| US4645759A (en) * | 1984-06-22 | 1987-02-24 | Abbott Laboratories | Renin inhibiting compounds |
| EP0181110A3 (en) * | 1984-10-22 | 1988-05-11 | Kissei Pharmaceutical Co. Ltd. | Histidine derivatives as renin inhibitors |
| DK34086A (da) * | 1985-01-23 | 1986-07-24 | Abbott Lab | Peptidylaminodioler |
| JPS61236770A (ja) * | 1985-04-15 | 1986-10-22 | Kissei Pharmaceut Co Ltd | 新規なアミノ酸誘導体 |
| JPS6256458A (ja) * | 1985-09-04 | 1987-03-12 | Kissei Pharmaceut Co Ltd | 新規なアミノ酸誘導体 |
| IL81234A (en) * | 1986-01-16 | 1992-09-06 | Abbott Lab | Peptidylaminodiols,process for their preparation and pharmaceutical compositions comprising them |
| EP0258289A4 (en) * | 1986-01-16 | 1991-01-02 | Joseph Dellaria | Peptide analogs |
| US4921855A (en) * | 1987-06-22 | 1990-05-01 | Fujisawa Pharmaceutical Co., Ltd. | New Histidyl amino acid derivatives, and pharmaceutical composition comprising the same |
| IL87614A0 (en) * | 1987-09-16 | 1989-01-31 | Abbott Lab | Peptidylheterocycles |
-
1988
- 1988-07-01 US US07/214,698 patent/US4900746A/en not_active Expired - Lifetime
-
1989
- 1989-06-28 KR KR1019890008972A patent/KR900001720A/ko not_active Withdrawn
- 1989-06-29 PT PT91022A patent/PT91022A/pt unknown
- 1989-06-30 ZA ZA895000A patent/ZA895000B/xx unknown
- 1989-06-30 DK DK327089A patent/DK327089A/da not_active Application Discontinuation
- 1989-07-03 NO NO892744A patent/NO892744D0/no unknown
- 1989-07-03 PT PT91045A patent/PT91045B/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PT91022A (pt) | 1990-02-08 |
| DK327089A (da) | 1990-01-02 |
| ZA895000B (en) | 1990-09-26 |
| KR900001720A (ko) | 1990-02-27 |
| US4900746A (en) | 1990-02-13 |
| PT91045B (pt) | 1994-12-30 |
| DK327089D0 (da) | 1989-06-30 |
| NO892744D0 (no) | 1989-07-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Patent granted, date of granting |
Effective date: 19940620 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19951231 |