PT90133A - Processo para a preparacao de {4-{2-(4-c1-4 alquiloxifenil)-2-(1h-imidazol-1-ilmetil)-1,3-dioxolam-4-ilmetiltio}fenil}-carbamatos de alquilo e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de {4-{2-(4-c1-4 alquiloxifenil)-2-(1h-imidazol-1-ilmetil)-1,3-dioxolam-4-ilmetiltio}fenil}-carbamatos de alquilo e de composicoes farmaceuticas que os contem

Info

Publication number
PT90133A
PT90133A PT90133A PT9013389A PT90133A PT 90133 A PT90133 A PT 90133A PT 90133 A PT90133 A PT 90133A PT 9013389 A PT9013389 A PT 9013389A PT 90133 A PT90133 A PT 90133A
Authority
PT
Portugal
Prior art keywords
ilmetilthy
dioxolam
alyloxyphenyl
ylethyl
carbamates
Prior art date
Application number
PT90133A
Other languages
English (en)
Other versions
PT90133B (pt
Inventor
Willem Hendrik Kare Distelmans
Jan Heeres
Robert Franciscus Van Ginckel
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888807314A external-priority patent/GB8807314D0/en
Priority claimed from GB888829966A external-priority patent/GB8829966D0/en
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of PT90133A publication Critical patent/PT90133A/pt
Publication of PT90133B publication Critical patent/PT90133B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT90133A 1988-03-28 1989-03-28 Processo para a preparacao de {4-{2-(4-c1-4 alquiloxifenil)-2-(1h-imidazol-1-ilmetil)-1,3-dioxolam-4-ilmetiltio}fenil}-carbamatos de alquilo e de composicoes farmaceuticas que os contem PT90133B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888807314A GB8807314D0 (en) 1988-03-28 1988-03-28 Method of treating neoplasms
GB888829966A GB8829966D0 (en) 1988-12-22 1988-12-22 Method of treating neoplasms

Publications (2)

Publication Number Publication Date
PT90133A true PT90133A (pt) 1989-11-10
PT90133B PT90133B (pt) 1994-07-29

Family

ID=26293700

Family Applications (1)

Application Number Title Priority Date Filing Date
PT90133A PT90133B (pt) 1988-03-28 1989-03-28 Processo para a preparacao de {4-{2-(4-c1-4 alquiloxifenil)-2-(1h-imidazol-1-ilmetil)-1,3-dioxolam-4-ilmetiltio}fenil}-carbamatos de alquilo e de composicoes farmaceuticas que os contem

Country Status (7)

Country Link
EP (1) EP0335446A3 (pt)
JP (1) JPH0725752B2 (pt)
AU (1) AU614818B2 (pt)
DK (1) DK146389A (pt)
IL (1) IL89747A0 (pt)
NZ (1) NZ228335A (pt)
PT (1) PT90133B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5158949A (en) * 1990-12-20 1992-10-27 Syntex (U.S.A.) Inc. 1,3-dioxolane derivatives as cholesterol-lowering agents
US5208331A (en) * 1992-06-18 1993-05-04 Syntex (U.S.A.) Inc. Process for preparing 1,3-dioxolane derivatives
US5274108A (en) * 1992-06-18 1993-12-28 Syntex (U.S.A.) Inc. Process for preparing 1,3-dioxolane derivatives
EP0764430A2 (en) * 1995-09-21 1997-03-26 Anchor Advanced Products, Inc. Wax filled dental floss

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3936470A (en) * 1975-01-27 1976-02-03 Janssen Pharmaceutica N.V. 1,3-Dioxolan-2-ylmethylimidazoles
US4144346A (en) * 1977-01-31 1979-03-13 Janssen Pharmaceutica N.V. Novel 1-(1,3-dioxolan-2-ylmethyl)-1H-imidazoles
DE3166517D1 (de) * 1980-11-24 1984-11-08 Janssen Pharmaceutica Nv Novel (2-aryl-4-phenylthioalkyl-1,3-dioxolan-2-yl-methyl)azole derivatives

Also Published As

Publication number Publication date
DK146389A (da) 1989-09-29
NZ228335A (en) 1990-11-27
DK146389D0 (da) 1989-03-22
AU3114189A (en) 1989-09-28
EP0335446A2 (en) 1989-10-04
JPH01299286A (ja) 1989-12-04
PT90133B (pt) 1994-07-29
IL89747A0 (en) 1989-09-28
JPH0725752B2 (ja) 1995-03-22
EP0335446A3 (en) 1991-04-03
AU614818B2 (en) 1991-09-12

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PT90133A (pt) Processo para a preparacao de {4-{2-(4-c1-4 alquiloxifenil)-2-(1h-imidazol-1-ilmetil)-1,3-dioxolam-4-ilmetiltio}fenil}-carbamatos de alquilo e de composicoes farmaceuticas que os contem

Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19940103

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19960731