PT90019A - Processo para a preparacao e purificacao de factor de choque termico humano - Google Patents

Processo para a preparacao e purificacao de factor de choque termico humano

Info

Publication number
PT90019A
PT90019A PT90019A PT9001989A PT90019A PT 90019 A PT90019 A PT 90019A PT 90019 A PT90019 A PT 90019A PT 9001989 A PT9001989 A PT 9001989A PT 90019 A PT90019 A PT 90019A
Authority
PT
Portugal
Prior art keywords
purification
preparation
shock factor
thermal shock
human thermal
Prior art date
Application number
PT90019A
Other languages
English (en)
Other versions
PT90019B (pt
Inventor
Robert E Kingston
Thomas J Schuetz
Original Assignee
Gen Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/301,417 external-priority patent/US5137805A/en
Application filed by Gen Hospital Corp filed Critical Gen Hospital Corp
Publication of PT90019A publication Critical patent/PT90019A/pt
Publication of PT90019B publication Critical patent/PT90019B/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43509—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from crustaceans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Toxicology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • Insects & Arthropods (AREA)
  • Physics & Mathematics (AREA)
  • Vascular Medicine (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
PT90019A 1988-03-18 1989-03-16 Processo para a preparacao e purificacao de factor de choque termico humano PT90019B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16996588A 1988-03-18 1988-03-18
US07/301,417 US5137805A (en) 1988-03-18 1989-01-25 Method of diagnosing stress condition by specific binding of human heat shock factor

Publications (2)

Publication Number Publication Date
PT90019A true PT90019A (pt) 1990-11-20
PT90019B PT90019B (pt) 1994-11-30

Family

ID=26865545

Family Applications (1)

Application Number Title Priority Date Filing Date
PT90019A PT90019B (pt) 1988-03-18 1989-03-16 Processo para a preparacao e purificacao de factor de choque termico humano

Country Status (11)

Country Link
EP (1) EP0333201B1 (pt)
JP (1) JPH03503410A (pt)
AT (1) ATE112168T1 (pt)
AU (1) AU645243B2 (pt)
DE (1) DE68918479T2 (pt)
DK (1) DK224790A (pt)
ES (1) ES2064375T3 (pt)
FI (1) FI904564A0 (pt)
IE (1) IE62447B1 (pt)
PT (1) PT90019B (pt)
WO (1) WO1989008661A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2845623B2 (ja) * 1990-11-26 1999-01-13 アメリカ合衆国 細胞のストレス転写因子
FI92601C (fi) * 1992-03-11 1994-12-12 Marja Makarow Menetelmä hyötyproteiinien erittämiseksi hiivoista
GB9402857D0 (en) 1994-02-15 1994-04-06 Isis Innovation Targeting gene therapy
AU751359B2 (en) * 1997-07-10 2002-08-15 Medical Research Council Chaperone fragments
CA2273081A1 (en) * 1997-09-29 1999-04-08 Tetsuya Mori Method for screening heat shock protein expression induction regulators
EP2318032B1 (en) * 2008-06-26 2012-04-04 Orphazyme APS Use of hsp70 as a regulator of enzymatic activity
CN109069496A (zh) 2016-04-29 2018-12-21 奥菲泽米有限公司 用于治疗葡糖脑苷脂酶相关疾病的arimoclomol
WO2022106614A1 (en) 2020-11-19 2022-05-27 Orphazyme A/S Processes for preparing arimoclomol citrate and intermediates thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4603106A (en) * 1982-02-22 1986-07-29 The Rockefeller University Lipoprotein lipase suppression by endotoxin-induced mediator (shock assay)
US4701406A (en) * 1984-11-16 1987-10-20 Trustees Of Boston University Assay for the detection of epigenetic toxic (non-genotoxic) substances

Also Published As

Publication number Publication date
ATE112168T1 (de) 1994-10-15
DE68918479T2 (de) 1995-03-02
IE62447B1 (en) 1995-02-08
DK224790D0 (da) 1990-09-18
EP0333201A2 (en) 1989-09-20
FI904564A0 (fi) 1990-09-17
DK224790A (da) 1990-11-15
IE890817L (en) 1989-09-18
PT90019B (pt) 1994-11-30
ES2064375T3 (es) 1995-02-01
WO1989008661A1 (en) 1989-09-21
AU3280489A (en) 1989-10-05
EP0333201A3 (en) 1990-05-09
AU645243B2 (en) 1994-01-13
JPH03503410A (ja) 1991-08-01
DE68918479D1 (de) 1994-11-03
EP0333201B1 (en) 1994-09-28

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19940524

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19971130

NF3A Restitutio in integrum

Effective date: 19980401

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19991130