PT89955A - Processo para a preparacao de acidos 1-ciclopropil-quinolonocarboxilicos e seus derivados, e de n-ciclopropilanilinas utilizadas nesse processo - Google Patents
Processo para a preparacao de acidos 1-ciclopropil-quinolonocarboxilicos e seus derivados, e de n-ciclopropilanilinas utilizadas nesse processoInfo
- Publication number
- PT89955A PT89955A PT89955A PT8995589A PT89955A PT 89955 A PT89955 A PT 89955A PT 89955 A PT89955 A PT 89955A PT 8995589 A PT8995589 A PT 8995589A PT 89955 A PT89955 A PT 89955A
- Authority
- PT
- Portugal
- Prior art keywords
- quinolonocarboxylic
- cyclopopilanilins
- cyclopropyl
- derivatives
- acids
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3808117A DE3808117A1 (de) | 1988-03-11 | 1988-03-11 | N-cyclopropylaniline und deren verwendung in verfahren zur herstellung von 1-cyclopropyl-chinoloncarbonsaeuren und deren derivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT89955A true PT89955A (pt) | 1989-11-10 |
Family
ID=6349470
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT89955A PT89955A (pt) | 1988-03-11 | 1989-03-09 | Processo para a preparacao de acidos 1-ciclopropil-quinolonocarboxilicos e seus derivados, e de n-ciclopropilanilinas utilizadas nesse processo |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0332033A2 (pt) |
| JP (1) | JPH024778A (pt) |
| KR (1) | KR890014486A (pt) |
| CN (1) | CN1037147A (pt) |
| DE (1) | DE3808117A1 (pt) |
| FI (1) | FI891122A (pt) |
| HU (1) | HUT50781A (pt) |
| IL (1) | IL89534A0 (pt) |
| PT (1) | PT89955A (pt) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2046091B1 (es) * | 1991-09-24 | 1994-09-01 | Elmuquimica Farm Sl | Nuevo procedimiento de obtencion del acido 1-ciclopropil-6-fluoro-1,4-dihidro-4-oxo-7-(1-piperacinil)-3-quinolin carboxilico. |
| ES2050613B1 (es) * | 1992-10-16 | 1996-03-16 | Iteve S A | Nuevo procedimiento para la preparacion de derivados del acido 1-ciclopropil-3-quinolincarboxilico. |
| HUT67395A (en) * | 1993-07-13 | 1995-04-28 | Somfai | Method for the n-cyclopropylation of primary and secondary aromatic amines |
| DE19720541A1 (de) | 1997-05-16 | 1998-11-19 | Bayer Ag | Verfahren zur kontinuierlichen Herstellung von Dihydroxydiphenylalkanen |
| DE19720540A1 (de) | 1997-05-16 | 1998-11-19 | Bayer Ag | Verfahren zur Aufarbeitung von Mutterlaugen aus der Bisphenolsynthese |
| JP2000229946A (ja) * | 1998-12-10 | 2000-08-22 | Toyama Chem Co Ltd | キノロンカルボン酸の製造法およびその中間体 |
| US20100074949A1 (en) | 2008-08-13 | 2010-03-25 | William Rowe | Pharmaceutical composition and administration thereof |
| US8354427B2 (en) | 2004-06-24 | 2013-01-15 | Vertex Pharmaceutical Incorporated | Modulators of ATP-binding cassette transporters |
| CN107501099B (zh) | 2004-06-24 | 2021-03-19 | 沃泰克斯药物股份有限公司 | Atp-结合弹夹转运蛋白的调控剂 |
| PL1993360T3 (pl) | 2005-12-28 | 2017-08-31 | Vertex Pharmaceuticals Incorporated | Stałe postacie n-[2,4-bis(1,1-dimetyloetylo)-5-hydroksyfenylo]-1,4- dihydro-4-oksochinolino-3-karboksyamidu |
| WO2010065905A2 (en) * | 2008-12-05 | 2010-06-10 | Oregon Health & Science University | Compounds having antiparasitic or anti-infectious activity |
| US8598354B2 (en) | 2008-12-05 | 2013-12-03 | University Of South Florida | Compounds having antiparasitic or anti-infectious activity |
| KR101955863B1 (ko) | 2009-03-20 | 2019-03-07 | 버텍스 파마슈티칼스 인코포레이티드 | 낭성 섬유증 막횡단 전도도 조절자의 조정자의 제조 방법 |
| US8802700B2 (en) | 2010-12-10 | 2014-08-12 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-Binding Cassette transporters |
| IL265430B2 (en) | 2012-02-27 | 2024-08-01 | Vertex Pharma | Pharmaceutical preparations containing a solid dispersion of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide and uses thereof |
| AU2015330923B2 (en) | 2014-10-07 | 2020-03-12 | Vertex Pharmaceuticals Incorporated | Co-crystals of modulators of cystic fibrosis transmembrane conductance regulator |
-
1988
- 1988-03-11 DE DE3808117A patent/DE3808117A1/de not_active Withdrawn
-
1989
- 1989-03-01 EP EP89103547A patent/EP0332033A2/de not_active Withdrawn
- 1989-03-02 JP JP1048690A patent/JPH024778A/ja active Pending
- 1989-03-08 IL IL89534A patent/IL89534A0/xx unknown
- 1989-03-09 PT PT89955A patent/PT89955A/pt not_active Application Discontinuation
- 1989-03-09 FI FI891122A patent/FI891122A/fi not_active Application Discontinuation
- 1989-03-10 KR KR1019890002951A patent/KR890014486A/ko not_active IP Right Cessation
- 1989-03-10 HU HU891182A patent/HUT50781A/hu unknown
- 1989-03-11 CN CN89103163A patent/CN1037147A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FI891122A (fi) | 1989-09-12 |
| JPH024778A (ja) | 1990-01-09 |
| HUT50781A (en) | 1990-03-28 |
| KR890014486A (ko) | 1989-10-24 |
| EP0332033A2 (de) | 1989-09-13 |
| CN1037147A (zh) | 1989-11-15 |
| IL89534A0 (en) | 1989-09-10 |
| FI891122A0 (fi) | 1989-03-09 |
| DE3808117A1 (de) | 1989-09-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC3A | Refusal |
Effective date: 19940408 |