PT88373A - Procede de preparation d'imidazo <1,2-b> pyridazines et de compositions pharmaceutiques les contenant - Google Patents

Procede de preparation d'imidazo <1,2-b> pyridazines et de compositions pharmaceutiques les contenant

Info

Publication number
PT88373A
PT88373A PT88373A PT8837388A PT88373A PT 88373 A PT88373 A PT 88373A PT 88373 A PT88373 A PT 88373A PT 8837388 A PT8837388 A PT 8837388A PT 88373 A PT88373 A PT 88373A
Authority
PT
Portugal
Prior art keywords
pyridazines
imidazo
alkyl group
procede
preparation
Prior art date
Application number
PT88373A
Other languages
English (en)
Other versions
PT88373B (pt
Inventor
Jean-Jacques Bourguignon
Camille Georges Wermuth
Paul Worms
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of PT88373A publication Critical patent/PT88373A/pt
Publication of PT88373B publication Critical patent/PT88373B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PT88373A 1987-09-01 1988-08-30 Processo para a preparacao de imidazo{1,2-b}piridazinas e de composicoes farmaceuticas que as contem PT88373B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8712167A FR2619818B1 (fr) 1987-09-01 1987-09-01 Imidazo (1,2-b) pyridazines, procede pour leur preparation et compositions pharmaceutiques les contenant

Publications (2)

Publication Number Publication Date
PT88373A true PT88373A (pt) 1989-07-31
PT88373B PT88373B (pt) 1992-10-30

Family

ID=9354553

Family Applications (1)

Application Number Title Priority Date Filing Date
PT88373A PT88373B (pt) 1987-09-01 1988-08-30 Processo para a preparacao de imidazo{1,2-b}piridazinas e de composicoes farmaceuticas que as contem

Country Status (8)

Country Link
US (1) US4910199A (pt)
EP (1) EP0306408B1 (pt)
JP (1) JPS6471877A (pt)
AT (1) ATE73803T1 (pt)
CA (1) CA1310318C (pt)
DE (1) DE3869286D1 (pt)
FR (1) FR2619818B1 (pt)
PT (1) PT88373B (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601011B1 (fr) * 1986-07-03 1988-10-28 Sanofi Sa Nouveaux derives tricycliques agonistes des recepteurs cholinergiques et medicaments en contenant
FR2625201B1 (fr) * 1987-12-24 1990-06-15 Sanofi Sa Nouveaux derives tricycliques agonistes des recepteurs cholinergiques et medicaments en contenant
EP0809642A1 (en) * 1995-02-15 1997-12-03 PHARMACIA &amp; UPJOHN COMPANY Imidazo 1,2-a]pyridines for the treatment of cns and cardiac diseases
US6013654A (en) * 1997-08-14 2000-01-11 Pharmacia & Upjohn Company Imidazo[1,2-A]pyridines for the treatment of CNS and cardiac diseases
TWI312347B (en) * 2001-02-08 2009-07-21 Eisai R&D Man Co Ltd Bicyclic nitrogen-containing condensed ring compounds
US7723336B2 (en) 2005-09-22 2010-05-25 Bristol-Myers Squibb Company Fused heterocyclic compounds useful as kinase modulators
US20070078136A1 (en) * 2005-09-22 2007-04-05 Bristol-Myers Squibb Company Fused heterocyclic compounds useful as kinase modulators
JP5394404B2 (ja) 2008-02-06 2014-01-22 ブリストル−マイヤーズ スクイブ カンパニー キナーゼ阻害剤として有用な置換イミダゾピリダジン類
KR20100128305A (ko) * 2008-02-28 2010-12-07 노파르티스 아게 Ｃ-ｍｅｔ 티로신 키나제 매개 질환의 치료를 위한 이미다조[1,2-ｂ]피리다진 유도체
CN102007133B (zh) * 2008-04-15 2013-06-12 卫材R&D管理有限公司 3-苯基吡唑并[5,1-b]噻唑化合物
US8389526B2 (en) 2009-08-07 2013-03-05 Novartis Ag 3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
AR078521A1 (es) * 2009-10-08 2011-11-16 Eisai R&D Man Co Ltd Compuesto pirazolotiazol
JPWO2011043387A1 (ja) * 2009-10-08 2013-03-04 エーザイ・アール・アンド・ディー・マネジメント株式会社 ピラゾロオキサゾール化合物
UA117092C2 (uk) 2011-09-06 2018-06-25 Байєр Інтеллектуал Проперті Гмбх Амінозаміщені імідазопіридазини
ES2646916T3 (es) 2012-11-19 2017-12-18 Bayer Pharma Aktiengesellschaft Aminoimidazopiridazinas como inhibidores de MKNK1 cinasa

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3489755A (en) * 1966-08-03 1970-01-13 Pfizer & Co C Imidazo (1,2-b) pyridazines
US3828041A (en) * 1971-02-24 1974-08-06 American Cyanamid Co 6-substituted 3-nitroimidazo(1,2-b)pyridazines and method of preparing same
FR2473522A1 (fr) * 1980-01-16 1981-07-17 Synthelabo Nouveaux derives substitues de dihydro-2,3 imidazo(1,2-b)pyridazines et les medicaments, utiles notamment comme antidepresseurs, qui en contiennent
US4464372A (en) * 1982-08-16 1984-08-07 Schering Corporation Imidazo[1,2-b]pyridazines
US4569934A (en) * 1984-10-09 1986-02-11 American Cyanamid Company Imidazo[1,2-b]pyridazines

Also Published As

Publication number Publication date
CA1310318C (en) 1992-11-17
FR2619818B1 (fr) 1990-01-12
EP0306408B1 (fr) 1992-03-18
US4910199A (en) 1990-03-20
ATE73803T1 (de) 1992-04-15
EP0306408A1 (fr) 1989-03-08
DE3869286D1 (de) 1992-04-23
JPS6471877A (en) 1989-03-16
PT88373B (pt) 1992-10-30
FR2619818A1 (fr) 1989-03-03

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19920413

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19931031