PT88041A - Processo para a preparacao de derivados do acido hidrocinamico e de composicoes farmaceuticas que os contem - Google Patents
Processo para a preparacao de derivados do acido hidrocinamico e de composicoes farmaceuticas que os contemInfo
- Publication number
- PT88041A PT88041A PT88041A PT8804188A PT88041A PT 88041 A PT88041 A PT 88041A PT 88041 A PT88041 A PT 88041A PT 8804188 A PT8804188 A PT 8804188A PT 88041 A PT88041 A PT 88041A
- Authority
- PT
- Portugal
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- hydrocinamic
- acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/30—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms
- C07C233/31—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH276487 | 1987-07-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT88041A true PT88041A (pt) | 1989-06-30 |
Family
ID=4241087
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT88041A PT88041A (pt) | 1987-07-21 | 1988-07-20 | Processo para a preparacao de derivados do acido hidrocinamico e de composicoes farmaceuticas que os contem |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US4883815A (pt) |
| EP (1) | EP0300371A1 (pt) |
| JP (1) | JPS6447748A (pt) |
| KR (1) | KR890001954A (pt) |
| CN (1) | CN1015622B (pt) |
| AU (1) | AU603470B2 (pt) |
| DD (1) | DD277071A5 (pt) |
| DK (1) | DK405888A (pt) |
| FI (1) | FI883441A (pt) |
| GB (1) | GB2207135B (pt) |
| HU (1) | HU198676B (pt) |
| IL (1) | IL87130A0 (pt) |
| IN (1) | IN167395B (pt) |
| IS (1) | IS3376A7 (pt) |
| MC (1) | MC1960A1 (pt) |
| MT (1) | MTP1023B (pt) |
| MW (1) | MW2688A1 (pt) |
| NO (1) | NO883233L (pt) |
| NZ (1) | NZ225442A (pt) |
| OA (1) | OA08746A (pt) |
| PT (1) | PT88041A (pt) |
| TN (1) | TNSN88076A1 (pt) |
| YU (2) | YU141488A (pt) |
| ZA (1) | ZA885102B (pt) |
| ZW (1) | ZW9288A1 (pt) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2125884T3 (es) * | 1991-08-21 | 1999-03-16 | Lilly Co Eli | Hexahidrobenzo(f)quinolinonas como inhibidores de la 5-alfa-reductasa. |
| US5239075A (en) * | 1991-08-21 | 1993-08-24 | Eli Lilly And Company | Process for the preparation of benzo (f) quinolinones |
| US5250539A (en) * | 1991-08-21 | 1993-10-05 | Eli Lilly And Company | Hexahydrobenzo[f]quinolinones |
| KR950701312A (ko) * | 1992-05-12 | 1995-03-23 | 이베 사치아키 | 신규 4급 암모늄염 및 약제로서 그의 사용 |
| US6172235B1 (en) | 1996-08-09 | 2001-01-09 | Merck & Co., Inc. | Asymmetric conjugate addition reaction |
| US5849914A (en) * | 1996-08-09 | 1998-12-15 | Merck & Co., Inc. | Compounds formed by an asymmetric conjugate addition reaction |
| ATE251611T1 (de) * | 1996-08-09 | 2003-10-15 | Merck & Co Inc | Additionsreaktion mit asymmetrischem konjugat |
| GB9920872D0 (en) * | 1999-09-04 | 1999-11-10 | Glaxo Group Ltd | Benzophenones as inhibitors of reverse transcriptase |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3795683A (en) * | 1970-08-19 | 1974-03-05 | Hoffmann La Roche | 2,3,4,5-tetrahydro-1h-3-benzazepines |
| JPS6033439B2 (ja) * | 1980-03-07 | 1985-08-02 | 財団法人相模中央化学研究所 | ジペプチドの製造方法 |
| IT1175926B (it) * | 1984-01-13 | 1987-08-12 | Debi Derivati Biologici | Procedimento per la preparazione dell'estere metilico di alfa-l-aspartil-l-fenilalanina |
| DE3773950D1 (de) * | 1986-01-23 | 1991-11-28 | Hoffmann La Roche | Benzazecin-derivate. |
-
1988
- 1988-06-22 IN IN425/MAS/88A patent/IN167395B/en unknown
- 1988-07-05 MW MW26/88A patent/MW2688A1/xx unknown
- 1988-07-05 US US07/215,003 patent/US4883815A/en not_active Expired - Fee Related
- 1988-07-06 MT MT1023A patent/MTP1023B/xx unknown
- 1988-07-06 ZW ZW92/88A patent/ZW9288A1/xx unknown
- 1988-07-14 ZA ZA885102A patent/ZA885102B/xx unknown
- 1988-07-14 EP EP88111347A patent/EP0300371A1/de not_active Withdrawn
- 1988-07-15 IL IL87130A patent/IL87130A0/xx unknown
- 1988-07-18 MC MC881992A patent/MC1960A1/xx unknown
- 1988-07-18 TN TNTNSN88076A patent/TNSN88076A1/fr unknown
- 1988-07-18 NZ NZ225442A patent/NZ225442A/en unknown
- 1988-07-18 AU AU19176/88A patent/AU603470B2/en not_active Ceased
- 1988-07-18 HU HU883759A patent/HU198676B/hu not_active IP Right Cessation
- 1988-07-19 KR KR1019880008982A patent/KR890001954A/ko not_active Application Discontinuation
- 1988-07-19 DD DD88318084A patent/DD277071A5/de not_active IP Right Cessation
- 1988-07-20 CN CN88104521A patent/CN1015622B/zh not_active Expired
- 1988-07-20 JP JP63179300A patent/JPS6447748A/ja active Pending
- 1988-07-20 NO NO88883233A patent/NO883233L/no unknown
- 1988-07-20 IS IS3376A patent/IS3376A7/is unknown
- 1988-07-20 DK DK405888A patent/DK405888A/da not_active Application Discontinuation
- 1988-07-20 GB GB8817291A patent/GB2207135B/en not_active Expired - Fee Related
- 1988-07-20 PT PT88041A patent/PT88041A/pt not_active Application Discontinuation
- 1988-07-20 FI FI883441A patent/FI883441A/fi not_active IP Right Cessation
- 1988-07-21 OA OA59392A patent/OA08746A/xx unknown
- 1988-07-21 YU YU01414/88A patent/YU141488A/xx unknown
-
1989
- 1989-09-06 US US07/403,532 patent/US5017608A/en not_active Expired - Fee Related
-
1990
- 1990-03-01 YU YU00398/90A patent/YU39890A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR890001954A (ko) | 1989-04-06 |
| EP0300371A1 (de) | 1989-01-25 |
| ZA885102B (en) | 1989-03-29 |
| ZW9288A1 (en) | 1989-02-01 |
| TNSN88076A1 (fr) | 1990-07-10 |
| CN1015622B (zh) | 1992-02-26 |
| OA08746A (fr) | 1989-03-31 |
| AU1917688A (en) | 1989-01-27 |
| DD277071A5 (de) | 1990-03-21 |
| CN1036952A (zh) | 1989-11-08 |
| GB2207135B (en) | 1991-05-15 |
| MC1960A1 (fr) | 1989-06-30 |
| YU141488A (en) | 1990-06-30 |
| NO883233L (no) | 1989-01-23 |
| IS3376A7 (is) | 1989-01-22 |
| IL87130A0 (en) | 1988-12-30 |
| JPS6447748A (en) | 1989-02-22 |
| IN167395B (pt) | 1990-10-20 |
| MW2688A1 (en) | 1989-04-12 |
| NO883233D0 (no) | 1988-07-20 |
| HU198676B (en) | 1989-11-28 |
| US4883815A (en) | 1989-11-28 |
| DK405888A (da) | 1989-01-22 |
| YU39890A (en) | 1991-10-31 |
| GB2207135A (en) | 1989-01-25 |
| US5017608A (en) | 1991-05-21 |
| AU603470B2 (en) | 1990-11-15 |
| FI883441A (fi) | 1989-01-22 |
| HUT47077A (en) | 1989-01-30 |
| NZ225442A (en) | 1991-05-28 |
| MTP1023B (en) | 1989-07-18 |
| DK405888D0 (da) | 1988-07-20 |
| FI883441A0 (fi) | 1988-07-20 |
| GB8817291D0 (en) | 1988-08-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC3A | Refusal |
Effective date: 19941115 |