PT87893A - Processo para a preparacao de novos derivados glucosidicos da epipodofilotoxina 3', 4-diazoto-substituidos e de composicoes farmaceuticas que os contem - Google Patents
Processo para a preparacao de novos derivados glucosidicos da epipodofilotoxina 3', 4-diazoto-substituidos e de composicoes farmaceuticas que os contemInfo
- Publication number
- PT87893A PT87893A PT87893A PT8789388A PT87893A PT 87893 A PT87893 A PT 87893A PT 87893 A PT87893 A PT 87893A PT 8789388 A PT8789388 A PT 8789388A PT 87893 A PT87893 A PT 87893A
- Authority
- PT
- Portugal
- Prior art keywords
- diazoto
- epipodophylotoxin
- substituted
- pharmaceutical compositions
- glucosidic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/068,376 US4874851A (en) | 1987-07-01 | 1987-07-01 | 3',4'-dinitrogen substituted epipodophyllotoxin glucoside derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT87893A true PT87893A (pt) | 1989-06-30 |
Family
ID=22082167
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT87893A PT87893A (pt) | 1987-07-01 | 1988-07-01 | Processo para a preparacao de novos derivados glucosidicos da epipodofilotoxina 3', 4-diazoto-substituidos e de composicoes farmaceuticas que os contem |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4874851A (pt) |
| EP (1) | EP0297594A3 (pt) |
| JP (1) | JPS6426592A (pt) |
| KR (1) | KR900006234B1 (pt) |
| AU (1) | AU618536B2 (pt) |
| CA (1) | CA1306250C (pt) |
| DK (1) | DK360888A (pt) |
| FI (1) | FI87357C (pt) |
| IL (1) | IL86888A0 (pt) |
| NO (1) | NO167807C (pt) |
| NZ (1) | NZ225089A (pt) |
| PT (1) | PT87893A (pt) |
| ZA (1) | ZA883762B (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4853467A (en) * | 1987-05-19 | 1989-08-01 | Bristol-Myers Company | Nitrogen containing derivatives of epipodophyllotoxin glucosides |
| US4904768A (en) * | 1987-08-04 | 1990-02-27 | Bristol-Myers Company | Epipodophyllotoxin glucoside 4'-phosphate derivatives |
| US4888419A (en) * | 1987-08-31 | 1989-12-19 | Bristol-Myers Company | 3'-demethoxyepipodophyllotoxin glucoside derivatives |
| US4965348A (en) * | 1989-05-19 | 1990-10-23 | Bristol-Myers Company | Dimeric epipodophyllotoxin glucoside derivatives |
| US5036055A (en) * | 1989-06-07 | 1991-07-30 | Bristol-Myers Company | Acylated derivatives of etoposide |
| US6207673B1 (en) | 1997-03-12 | 2001-03-27 | The University Of North Carolina At Chapel Hill | Covalent conjugates of topoisomerase I and topoisomerase II inhibitors |
| US6051721A (en) * | 1997-10-02 | 2000-04-18 | The Board Of Regents Of The University Of Nebraska | Ring E-modified analogues of(-)-podophyllotoxin and etoposide and a method for their synthesis |
| KR100377556B1 (ko) * | 1999-01-27 | 2003-03-26 | 주식회사 엘지생명과학 | 세픽심 제조에 유용한 중간체의 제조방법 |
| EP1229934B1 (en) | 1999-10-01 | 2014-03-05 | Immunogen, Inc. | Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL6613143A (pt) * | 1965-09-21 | 1967-03-22 | ||
| EP0111058B1 (en) * | 1982-11-26 | 1987-11-04 | Nippon Kayaku Kabushiki Kaisha | Process for producing 4'-demethyl-epipodophyllotoxin-beta-d-ethylidene-glucoside and acyl-derivative thereof |
| JPS6032799A (ja) * | 1983-07-29 | 1985-02-19 | Microbial Chem Res Found | 新規４′−デメチル−４−エピポドフィロトキシン誘導体 |
| JPS60246393A (ja) * | 1984-05-22 | 1985-12-06 | Nippon Kayaku Co Ltd | エトポシドの新規製造法 |
| US4609644A (en) * | 1984-06-15 | 1986-09-02 | St. Jude Children's Research Hospital | Epipodophyllotoxinquinone glucoside derivatives, method of production and use |
| JPS61227590A (ja) * | 1985-04-02 | 1986-10-09 | Microbial Chem Res Found | 新規４′−デメチル−４−エピポドフイロトキシン誘導体 |
| US4853467A (en) * | 1987-05-19 | 1989-08-01 | Bristol-Myers Company | Nitrogen containing derivatives of epipodophyllotoxin glucosides |
-
1987
- 1987-07-01 US US07/068,376 patent/US4874851A/en not_active Expired - Fee Related
-
1988
- 1988-05-26 ZA ZA883762A patent/ZA883762B/xx unknown
- 1988-06-20 NZ NZ225089A patent/NZ225089A/en unknown
- 1988-06-23 KR KR1019880007624A patent/KR900006234B1/ko not_active IP Right Cessation
- 1988-06-28 AU AU18446/88A patent/AU618536B2/en not_active Ceased
- 1988-06-28 FI FI883088A patent/FI87357C/fi not_active IP Right Cessation
- 1988-06-28 IL IL86888A patent/IL86888A0/xx unknown
- 1988-06-28 NO NO882849A patent/NO167807C/no unknown
- 1988-06-30 DK DK360888A patent/DK360888A/da not_active Application Discontinuation
- 1988-06-30 CA CA000570935A patent/CA1306250C/en not_active Expired - Fee Related
- 1988-06-30 JP JP63164102A patent/JPS6426592A/ja active Pending
- 1988-06-30 EP EP88110502A patent/EP0297594A3/en not_active Ceased
- 1988-07-01 PT PT87893A patent/PT87893A/pt not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NZ225089A (en) | 1991-06-25 |
| EP0297594A3 (en) | 1990-07-25 |
| AU618536B2 (en) | 1992-01-02 |
| NO167807C (no) | 1991-12-11 |
| CA1306250C (en) | 1992-08-11 |
| JPS6426592A (en) | 1989-01-27 |
| FI883088A (fi) | 1989-01-02 |
| FI883088A0 (fi) | 1988-06-28 |
| FI87357B (fi) | 1992-09-15 |
| FI87357C (fi) | 1992-12-28 |
| KR900006234B1 (ko) | 1990-08-27 |
| NO882849D0 (no) | 1988-06-28 |
| ZA883762B (en) | 1989-03-29 |
| IL86888A0 (en) | 1988-11-30 |
| NO167807B (no) | 1991-09-02 |
| EP0297594A2 (en) | 1989-01-04 |
| DK360888A (da) | 1989-01-02 |
| DK360888D0 (da) | 1988-06-30 |
| AU1844688A (en) | 1989-01-19 |
| KR890002215A (ko) | 1989-04-10 |
| NO882849L (no) | 1989-01-02 |
| US4874851A (en) | 1989-10-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PT81007B (pt) | Processo para a preparacao de derivados de 1,2-benzoisotiazolil-3-piperazina com accao analgesica e de composicoes farmaceuticas que os contem | |
| PT93094A (pt) | Processo para a preparacao de 1,3-oxatiolanos substituidos e de composicoes farmaceuticas que os contem | |
| PT92497A (pt) | Processo para a preparacao de derivados de ureia de dipeptideos inibidores de enzimas, e de composicoes farmaceuticas que os contem | |
| PT84449B (pt) | Processo para a preparacao de novos derivados 3,5-dissubstituidos do pirocatecol e de composicoes farmaceuticas que os contem | |
| PT88186A (pt) | Processo para a preparacao de derivados 4'-fosfato de glucosidos da epipodofilotoxina e de composicoes farmaceuticas que os contem | |
| PT99671A (pt) | Processo para a preparacao de heparosanos-n,o-sulfatados e de composicoes farmaceuticas que os contem | |
| PT99227A (pt) | Processo para a preparacao de derivados da quinazolina e de composicoes farmaceuticas que os contem | |
| PT80892B (pt) | Processo para a preparacao de derivados da quoinona e de composicoes farmaceuticas que os contem | |
| PT89497A (pt) | Processo para a preparacao de compostos piperidinilicos 1,4-dissubstituidos e de composicoes farmaceuticas que os contem | |
| PT82414B (pt) | Processo para a preparacao de agentes bactericidas a base de 5,6-difluoronaftiridinas e de 5,6,8-difluoroquinolinas e de composicoes farmaceuticas que os contem | |
| PT97114A (pt) | Processo para a preparacao de derivados de hidantoina e de composicoes farmaceuticas que os contem | |
| PT87968A (pt) | Processo para a preparacao de 5,6-dimetoxi-1,2-benzimidazolo-3-propanaminas substituidas em n e de compostos relacionados e de composicoes farmaceuticas que os contem | |
| PT101004A (pt) | Derivados da quinoxalina, processo para a sua preparacao e composicoes farmaceuticas que os contem | |
| PT82307B (pt) | Processo para a preparacao de derivados da 4'-demetil-4-epipodofilotoxina e de composicoes farmaceuticas que os contem | |
| PT84460B (pt) | Processo para a preparacao de derivados de ciclopropano 1,1-dissubstituidos e de composicoes farmaceuticas que os contem | |
| PT93067A (pt) | Processo para a preparacao de derivados de 2-hidroxiacidos alifaticos e de eteres de 1-benzil-3-hidroximetilindazol, e de composicoes farmaceuticas que os contem | |
| PT84187B (pt) | Processo para a preparacao de novos derivados da isoquinolina e de composicoes farmaceuticas que os contem | |
| PT90142A (pt) | Processo para a preparacao de novos imidazois substituidos em 2,3 e 4 e de 1,2,4-triazois substituido4 em 3,4 e 5 bem como de composicoes farmaceuticas que os contem | |
| PT84478B (pt) | Processo para a preparacao de derivados de pirazolo-{3,4-d}-pirimidina e de composicoes farmaceuticas que os contem | |
| PT84023B (pt) | Processo para a preparacao de novos derivados da 1-benzeno-sulfonil-2-oxo-alcoxi-pirrolidina e de composicoes farmaceuticas que os contem | |
| PT89145A (pt) | Processo para a preparacao de derivados da manumicina e de composicoes farmaceuticas que os contem | |
| PT90864A (pt) | Processo para a preparacao de derivados de cromano e de composicoes farmaceuticas que os contem | |
| PT91803A (pt) | Processo para a preparacao de novos derivados da 2'-halogenometilideno-, 2'-etenilideno- e 2'-etinil-adenosina e de composicoes farmaceuticas que os contem | |
| PT89715A (pt) | Processo para a preparacao de novos derivados de 1,4-benzoxazina e 1,4-benzotiazina e de composicoes farmaceuticas que os contem | |
| PT87893A (pt) | Processo para a preparacao de novos derivados glucosidicos da epipodofilotoxina 3', 4-diazoto-substituidos e de composicoes farmaceuticas que os contem |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC3A | Refusal |
Effective date: 19941115 |