PT86837A - Process for the preparation of novel heterocyclyl-2-propin-1-amines useful as dopamine beta-hydroxylase and of pharmaceutical compositions containing the same - Google Patents
Process for the preparation of novel heterocyclyl-2-propin-1-amines useful as dopamine beta-hydroxylase and of pharmaceutical compositions containing the sameInfo
- Publication number
- PT86837A PT86837A PT86837A PT8683788A PT86837A PT 86837 A PT86837 A PT 86837A PT 86837 A PT86837 A PT 86837A PT 8683788 A PT8683788 A PT 8683788A PT 86837 A PT86837 A PT 86837A
- Authority
- PT
- Portugal
- Prior art keywords
- propin
- hydroxylase
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1910387A | 1987-02-26 | 1987-02-26 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT86837A true PT86837A (pt) | 1988-03-01 |
| PT86837B PT86837B (pt) | 1992-05-29 |
Family
ID=21791457
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT86837A PT86837B (pt) | 1987-02-26 | 1988-02-25 | Processo para a preparacao de novas heterociclil-2-propino-1-aminas com accao inibidora da dopamina beta-hidroxilase e de composicoes farmaceuticas que as contem |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0281018A1 (pt) |
| JP (1) | JP2524513B2 (pt) |
| KR (1) | KR880009925A (pt) |
| CN (1) | CN88101039A (pt) |
| AU (1) | AU596501B2 (pt) |
| CA (1) | CA1309719C (pt) |
| DK (1) | DK98688A (pt) |
| FI (1) | FI880909A (pt) |
| HU (1) | HU200602B (pt) |
| IL (1) | IL85524A0 (pt) |
| NO (1) | NO880834L (pt) |
| NZ (1) | NZ223583A (pt) |
| PH (1) | PH23656A (pt) |
| PT (1) | PT86837B (pt) |
| ZA (1) | ZA881227B (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ214697A (en) * | 1984-12-31 | 1988-10-28 | Merrell Dow Pharma | B-methylene-2- and 3-furanethanamine and pharmaceutical compositions |
| JP3937489B2 (ja) * | 1996-05-31 | 2007-06-27 | 住友化学株式会社 | プロパルギルアミン化合物の製造方法 |
| CN103030580A (zh) * | 2012-12-13 | 2013-04-10 | 山东铂源药业有限公司 | 一种拉帕替尼中间体的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2299332A1 (fr) * | 1975-01-31 | 1976-08-27 | Parcor | Procede de preparation de la (thienyl-2)-2-ethylamine et de ses derives |
| FR2508456A1 (fr) * | 1981-06-30 | 1982-12-31 | Sanofi Sa | Procede de preparation de (thienyl-2)-2 ethylamines et (thienyl-3)-2 ethylamines |
| NZ214697A (en) * | 1984-12-31 | 1988-10-28 | Merrell Dow Pharma | B-methylene-2- and 3-furanethanamine and pharmaceutical compositions |
| NZ214698A (en) * | 1984-12-31 | 1988-08-30 | Merrell Dow Pharma | Thiophene derivatives and pharmaceutical compositions containing such |
| FR2608607B1 (fr) * | 1986-12-23 | 1989-04-28 | Sanofi Sa | Procede de preparation de thienylethylamines et dithienylethylamines ainsi obtenues |
-
1988
- 1988-02-22 ZA ZA881227A patent/ZA881227B/xx unknown
- 1988-02-22 NZ NZ223583A patent/NZ223583A/xx unknown
- 1988-02-22 CA CA000559481A patent/CA1309719C/en not_active Expired - Lifetime
- 1988-02-23 IL IL85524A patent/IL85524A0/xx unknown
- 1988-02-24 HU HU88887A patent/HU200602B/hu not_active IP Right Cessation
- 1988-02-24 PH PH36549A patent/PH23656A/en unknown
- 1988-02-24 KR KR1019880001900A patent/KR880009925A/ko not_active Application Discontinuation
- 1988-02-25 AU AU12173/88A patent/AU596501B2/en not_active Ceased
- 1988-02-25 NO NO880834A patent/NO880834L/no unknown
- 1988-02-25 PT PT86837A patent/PT86837B/pt not_active IP Right Cessation
- 1988-02-25 JP JP63040908A patent/JP2524513B2/ja not_active Expired - Fee Related
- 1988-02-25 DK DK098688A patent/DK98688A/da not_active Application Discontinuation
- 1988-02-25 EP EP88102814A patent/EP0281018A1/en not_active Withdrawn
- 1988-02-26 CN CN198888101039A patent/CN88101039A/zh active Pending
- 1988-02-26 FI FI880909A patent/FI880909A/fi not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PT86837B (pt) | 1992-05-29 |
| PH23656A (en) | 1989-09-27 |
| NO880834L (no) | 1988-08-29 |
| ZA881227B (en) | 1988-10-26 |
| DK98688A (da) | 1988-08-27 |
| JP2524513B2 (ja) | 1996-08-14 |
| HUT49337A (en) | 1989-09-28 |
| CA1309719C (en) | 1992-11-03 |
| CN88101039A (zh) | 1988-10-05 |
| FI880909A0 (fi) | 1988-02-26 |
| HU200602B (en) | 1990-07-28 |
| JPS63227581A (ja) | 1988-09-21 |
| NZ223583A (en) | 1990-02-26 |
| NO880834D0 (no) | 1988-02-25 |
| AU1217388A (en) | 1988-09-01 |
| EP0281018A1 (en) | 1988-09-07 |
| FI880909A (fi) | 1988-08-27 |
| AU596501B2 (en) | 1990-05-03 |
| DK98688D0 (da) | 1988-02-25 |
| IL85524A0 (en) | 1988-08-31 |
| KR880009925A (ko) | 1988-10-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Patent granted, date of granting |
Effective date: 19911115 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19940531 |