PT86830A - Process for preparing 3-amino-di-hydro-]1"-benzopyrans and benzothiopyrans and benzothiopyrans - Google Patents

Process for preparing 3-amino-di-hydro-]1"-benzopyrans and benzothiopyrans and benzothiopyrans

Info

Publication number
PT86830A
PT86830A PT86830A PT8683088A PT86830A PT 86830 A PT86830 A PT 86830A PT 86830 A PT86830 A PT 86830A PT 8683088 A PT8683088 A PT 8683088A PT 86830 A PT86830 A PT 86830A
Authority
PT
Portugal
Prior art keywords
compounds
lower alkyl
denotes
aryl
benzothiopyrans
Prior art date
Application number
PT86830A
Other languages
English (en)
Other versions
PT86830B (pt
Inventor
Alan J Hutchison
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of PT86830A publication Critical patent/PT86830A/pt
Publication of PT86830B publication Critical patent/PT86830B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D335/00Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06Benzothiopyrans; Hydrogenated benzothiopyrans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyrane Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Cephalosporin Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT86830A 1987-02-27 1988-02-25 Processo para a preparacao de 3-amino-di-hidro-{1}-benzo-piranos e benzotiopiranos PT86830B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/020,054 US4801605A (en) 1986-08-29 1987-02-27 3-amino-dihydro-[1]-benzopyrans and benzothiopyrans

Publications (2)

Publication Number Publication Date
PT86830A true PT86830A (pt) 1988-03-01
PT86830B PT86830B (pt) 1992-05-29

Family

ID=21796497

Family Applications (1)

Application Number Title Priority Date Filing Date
PT86830A PT86830B (pt) 1987-02-27 1988-02-25 Processo para a preparacao de 3-amino-di-hidro-{1}-benzo-piranos e benzotiopiranos

Country Status (20)

Country Link
US (1) US4801605A (pt)
EP (1) EP0280269B1 (pt)
JP (1) JPS63277671A (pt)
KR (1) KR880009953A (pt)
AT (1) ATE72563T1 (pt)
AU (1) AU612625B2 (pt)
DD (1) DD273256A5 (pt)
DE (1) DE3868329D1 (pt)
DK (1) DK100588A (pt)
ES (1) ES2038707T3 (pt)
FI (1) FI880866A (pt)
GR (1) GR3003800T3 (pt)
HU (1) HU201920B (pt)
IL (1) IL85494A0 (pt)
NO (1) NO880843L (pt)
NZ (1) NZ223647A (pt)
PH (1) PH23479A (pt)
PT (1) PT86830B (pt)
YU (1) YU36688A (pt)
ZA (1) ZA881375B (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0325964A1 (en) * 1988-01-15 1989-08-02 Abbott Laboratories Aminomethyl-chroman and -thiochroman compounds
EP0389425B1 (de) * 1989-03-22 1995-04-26 Ciba-Geigy Ag Neue Benzothiopyranylamine
JPH04504721A (ja) * 1989-04-27 1992-08-20 ジ・アップジョン・カンパニー 置換3―アミノ・クロマン類
US5306830A (en) * 1989-04-27 1994-04-26 The Upjohn Company Substituted 3-amino chromans
US5155130A (en) * 1989-08-11 1992-10-13 Ciba-Geigy Corporation Certain benzopyran and benzothiopyran derivatives
US5616610A (en) * 1989-12-22 1997-04-01 Astra Aktiebolag (R)-5-carbamoyl-8-fluoro-3-N,N-disubstituted-amino-3,4-dihydro-2H-1-benzopyrans
US5420151A (en) * 1989-12-22 1995-05-30 Aktiebolaget Astra Chroman derivatives
SE8904361D0 (sv) * 1989-12-22 1989-12-22 Astra Ab New chroman and thiochroman derivatives
EP0471515B1 (en) * 1990-08-15 1997-03-05 Eli Lilly And Company Ring-substituted 2-amino-1,2,3,4-tetra-hydronaphthalenes, 3-aminochromanes and 3-aminothiochromanes
US5348973A (en) * 1990-10-09 1994-09-20 Rhone-Poulenc Chimie Resolution of hydroxychroman-2-carboxylic acid esters by enantiomeric hydrolysis
US5120758A (en) * 1991-02-08 1992-06-09 Ciba-Geigy Corporation Certain benzodioxole, benzodioxane and benzodioxepin derivatives useful as 5-lipoxygenase inhibitors
DE69218813T2 (de) * 1991-02-08 1997-08-14 Lilly Co Eli Ringsubstituierte 2-Amino-1,2,3,4-tetrahydronaphthaline
DE4128690A1 (de) * 1991-08-29 1993-03-04 Boehringer Mannheim Gmbh Bicyclische sulfone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
HRP920935A2 (en) * 1991-10-08 1995-08-31 Astra Ab New therapeutically active compound
US5478857A (en) * 1993-12-23 1995-12-26 Eli Lilly And Company Use of PLA2 inhibitors as treatment for alzheimer's disease
IT1271009B (it) * 1994-09-13 1997-05-26 Zambon Spa Derivati del benzopirano e del benzotiopirano attivi sul sistema cardiovascolare
SE9701438D0 (sv) * 1997-04-17 1997-04-17 Astra Ab A new process
GB9801812D0 (en) * 1998-01-29 1998-03-25 Zeneca Ltd Chemical compounds
GB0426061D0 (en) * 2004-11-26 2004-12-29 Pfizer Ltd Chroman compounds
JP2011507835A (ja) 2007-12-21 2011-03-10 アンドレイ・アレクサンドロビッチ・イワシェンコ α−アドレナリン受容体、ドーパミン、ヒスタミン、イミダゾリン及びセロトニン受容体のリガンド並びにその使用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3142682A (en) * 1961-11-21 1964-07-28 Ciba Geigy Corp Tertiary amino derivatives of chromans and homo-chromans
GB1086101A (en) * 1965-01-19 1967-10-04 Ciba Ltd New chromans and process for preparing same
US3607886A (en) * 1969-04-24 1971-09-21 Parke Davis & Co Chromanamines
US3629289A (en) * 1969-04-24 1971-12-21 Parke Davis & Co Chromanamines
JPS561305B2 (pt) * 1972-12-18 1981-01-13
US4062870A (en) * 1974-05-31 1977-12-13 Beecham Group Limited Chroman derivatives
US4013771A (en) * 1975-12-15 1977-03-22 Warner-Lambert Company Substituted 2-aminothiochromones
LU79077A1 (de) * 1978-02-16 1979-09-06 Ciba Geigy Ag Verfahren zur herstellung neuer benzothiopyranderivate
US4203895A (en) * 1978-04-14 1980-05-20 Warner-Lambert Company Process for the preparation of cis-(±)-3,4-dihydro-N,N,2-trimethyl-2H-1-benzopyran-3-amine and intermediates produced thereby
US4232953A (en) * 1979-06-27 1980-11-11 Alvarez Sabater Fernando Gravity-feed rotary tray slide projector
IT1226045B (it) * 1981-07-29 1990-12-10 Simes Derivati tetraidrochinolici
DE3274350D1 (en) * 1981-09-25 1987-01-08 Beecham Group Plc Pharmaceutically active benzopyran compounds
FI79535C (fi) * 1982-05-06 1990-01-10 Erba Farmitalia Foerfarande foer framstaellning av dihydrobensopyrans och dihydrobensotiopyrans substituerade iminoderivat.
US4500545A (en) * 1982-11-16 1985-02-19 Eli Lilly And Company Hydroxyaminotetralincarboxamides
JPS59110690A (ja) * 1982-12-16 1984-06-26 Dai Ichi Seiyaku Co Ltd ベンゾピラン誘導体
US4657925A (en) * 1984-08-13 1987-04-14 Nelson Research & Development Co. Method and compositions for reducing the intraocular pressure of mammals
DE3583307D1 (en) * 1984-05-10 1991-08-01 Ciba Geigy Ag Benzo-(pyrano und thiopyrano)-pyridine.
US4736031A (en) * 1985-06-10 1988-04-05 Takeda Chemical Industries, Ltd. 2-(piperazinylalkyl)-1-benzothiepin, 1-benzoxepin, and 1,5-benzodioxepin derivatives
PH22522A (en) * 1985-09-03 1988-10-17 Ciba Geigy Ag 3-amino-dihydro-1-benzopyrans and benzothiopyrans, their pharmaceutical compositions and method of using said compounds
SE8605504D0 (sv) * 1986-12-19 1986-12-19 Astra Laekemedel Ab Novel chroman derivatives

Also Published As

Publication number Publication date
US4801605A (en) 1989-01-31
DE3868329D1 (de) 1992-03-26
AU612625B2 (en) 1991-07-18
PT86830B (pt) 1992-05-29
DK100588A (da) 1988-08-28
IL85494A0 (en) 1988-07-31
ES2038707T3 (es) 1993-08-01
EP0280269A1 (de) 1988-08-31
HU201920B (en) 1991-01-28
YU36688A (en) 1990-04-30
FI880866A (fi) 1988-08-28
NO880843L (no) 1988-08-29
JPS63277671A (ja) 1988-11-15
ATE72563T1 (de) 1992-02-15
FI880866A0 (fi) 1988-02-24
AU1234788A (en) 1988-09-01
NO880843D0 (no) 1988-02-26
DD273256A5 (de) 1989-11-08
ZA881375B (en) 1988-08-29
PH23479A (en) 1989-08-07
EP0280269B1 (de) 1992-02-12
GR3003800T3 (pt) 1993-03-16
NZ223647A (en) 1991-06-25
DK100588D0 (da) 1988-02-26
KR880009953A (ko) 1988-10-06

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19911113

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19930531