PT862575E - Novos derivados de geranilgeranilo processo para a sua preparacao e composicoes farmaceuticas relacionadas - Google Patents
Novos derivados de geranilgeranilo processo para a sua preparacao e composicoes farmaceuticas relacionadasInfo
- Publication number
- PT862575E PT862575E PT96941022T PT96941022T PT862575E PT 862575 E PT862575 E PT 862575E PT 96941022 T PT96941022 T PT 96941022T PT 96941022 T PT96941022 T PT 96941022T PT 862575 E PT862575 E PT 862575E
- Authority
- PT
- Portugal
- Prior art keywords
- relates
- preparing
- pharmaceutical composition
- derivatives
- novel
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/3804—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se) not used, see subgroups
- C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C307/00—Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C307/04—Diamides of sulfuric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C307/00—Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C307/04—Diamides of sulfuric acids
- C07C307/06—Diamides of sulfuric acids having nitrogen atoms of the sulfamide groups bound to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/3804—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se) not used, see subgroups
- C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
- C07F9/3821—Acyclic saturated acids which can have further substituents on alkyl substituted by B, Si, P or a metal
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/3804—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se) not used, see subgroups
- C07F9/3826—Acyclic unsaturated acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT95MI002431A IT1276162B1 (it) | 1995-11-23 | 1995-11-23 | Geranilgeranil-derivati,procedimento per la loro preparazione e relative composizioni farmaceutiche |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT862575E true PT862575E (pt) | 2004-06-30 |
Family
ID=11372579
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT96941022T PT862575E (pt) | 1995-11-23 | 1996-11-21 | Novos derivados de geranilgeranilo processo para a sua preparacao e composicoes farmaceuticas relacionadas |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6242433B1 (pt) |
| EP (1) | EP0862575B1 (pt) |
| JP (1) | JP2000500758A (pt) |
| AT (1) | ATE259369T1 (pt) |
| AU (1) | AU1031697A (pt) |
| BR (1) | BR9611642A (pt) |
| CA (1) | CA2238389C (pt) |
| DE (1) | DE69631542T2 (pt) |
| ES (1) | ES2216075T3 (pt) |
| IT (1) | IT1276162B1 (pt) |
| PT (1) | PT862575E (pt) |
| WO (1) | WO1997019091A1 (pt) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6117641A (en) | 1996-04-11 | 2000-09-12 | Mitotix, Inc. | Assays and reagents for identifying anti-fungal agents and uses related thereto |
| US6727082B1 (en) | 1996-04-11 | 2004-04-27 | Gpc Biotech Inc. | Assays and reagents for identifying anti-fungal agents, and uses related thereto |
| JP2001513622A (ja) | 1996-04-11 | 2001-09-04 | マイトティックス インコーポレーテッド | 抗菌剤の同定のためのアッセイおよび試薬、並びにそれらに関連する利用 |
| EP1089731A4 (en) * | 1998-06-24 | 2003-06-18 | Merck & Co Inc | COMPOSITIONS AND METHOD FOR TREATING INCREASED BLOOD CHOLESTEROL LEVELS |
| FR2781228B1 (fr) * | 1998-07-16 | 2000-09-29 | Pf Medicament | Phosphonates insatures derives d'indole |
| FR2833266B1 (fr) * | 2001-12-11 | 2004-10-22 | Mayoly Spindler Lab | Nouveaux derives phosphonates, leur procede de preparation, leur utilisation comme modulateurs de l'activite des lymphocytes tgamma9 delta2 |
| US20050065205A1 (en) * | 2002-03-07 | 2005-03-24 | Daniel Alkon | Methods for Alzheimer's disease treatment and cognitive enhance |
| DE10242106A1 (de) * | 2002-09-11 | 2004-04-15 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Phosphorgruppenhaltige Carbonsäurederivate mit organisch polymerisierbaren Gruppen |
| JP4691041B2 (ja) | 2003-11-20 | 2011-06-01 | チルドレンズ ホスピタル メディカル センター | Ｇｔｐアーゼ阻害剤および使用方法 |
| EP1920048A4 (en) | 2005-07-29 | 2009-12-09 | Childrens Hosp Medical Center | GTASE INHIBITORS AND USE METHOD AND CRYSTAL STRUCTURE OF RAC-1 GTASE |
| WO2013166043A1 (en) | 2012-05-02 | 2013-11-07 | Children's Hospital Medical Center | Rejuvenation of precursor cells |
| EP2870168B1 (en) * | 2012-07-05 | 2016-11-23 | University of Iowa Research Foundation | Therapeutic bisphosphonates |
| US10028503B2 (en) | 2014-06-18 | 2018-07-24 | Children's Hospital Medical Center | Platelet storage methods and compositions for same |
| WO2021178850A1 (en) * | 2020-03-06 | 2021-09-10 | Board Of Trustees Of Michigan State University | Method to produce the anti-microbial diterpenoid leubethanol and related serrulatane-type diterpenes |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0356866A3 (en) | 1988-08-29 | 1991-03-27 | E.R. SQUIBB & SONS, INC. | Phosphorus-containing squalene synthetase inhibitors and method |
| US5254715A (en) | 1990-11-07 | 1993-10-19 | Warner-Lambert Company | Aminosulfonyl carbamates |
| JPH05239075A (ja) | 1991-08-27 | 1993-09-17 | Eisai Co Ltd | 含リンイソプレノイド誘導体 |
| US5298655A (en) | 1991-09-27 | 1994-03-29 | Merck & Co., Inc. | Farnesyl pyrophosphate analogs |
| WO1994019357A1 (en) | 1993-02-23 | 1994-09-01 | Merrell Dow Pharmaceuticals Inc. | Farnesyl:protein transferase inhibitors as anticancer agents |
| US5510510A (en) * | 1994-05-10 | 1996-04-23 | Bristol-Meyers Squibb Company | Inhibitors of farnesyl protein transferase |
| US5574025A (en) | 1994-10-26 | 1996-11-12 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferases |
-
1995
- 1995-11-23 IT IT95MI002431A patent/IT1276162B1/it active IP Right Grant
-
1996
- 1996-11-21 AT AT96941022T patent/ATE259369T1/de not_active IP Right Cessation
- 1996-11-21 ES ES96941022T patent/ES2216075T3/es not_active Expired - Lifetime
- 1996-11-21 US US09/077,196 patent/US6242433B1/en not_active Expired - Fee Related
- 1996-11-21 CA CA002238389A patent/CA2238389C/en not_active Expired - Fee Related
- 1996-11-21 BR BR9611642A patent/BR9611642A/pt not_active IP Right Cessation
- 1996-11-21 EP EP96941022A patent/EP0862575B1/en not_active Expired - Lifetime
- 1996-11-21 AU AU10316/97A patent/AU1031697A/en not_active Abandoned
- 1996-11-21 WO PCT/EP1996/005202 patent/WO1997019091A1/en active IP Right Grant
- 1996-11-21 DE DE69631542T patent/DE69631542T2/de not_active Expired - Fee Related
- 1996-11-21 JP JP9519409A patent/JP2000500758A/ja active Granted
- 1996-11-21 PT PT96941022T patent/PT862575E/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IT1276162B1 (it) | 1997-10-27 |
| WO1997019091A1 (en) | 1997-05-29 |
| EP0862575B1 (en) | 2004-02-11 |
| US6242433B1 (en) | 2001-06-05 |
| BR9611642A (pt) | 1999-06-01 |
| ITMI952431A1 (it) | 1997-05-23 |
| DE69631542D1 (de) | 2004-03-18 |
| AU1031697A (en) | 1997-06-11 |
| DE69631542T2 (de) | 2004-12-30 |
| ATE259369T1 (de) | 2004-02-15 |
| EP0862575A1 (en) | 1998-09-09 |
| ES2216075T3 (es) | 2004-10-16 |
| CA2238389C (en) | 2005-10-18 |
| JP2000500758A (ja) | 2000-01-25 |
| CA2238389A1 (en) | 1997-05-29 |
| ITMI952431A0 (pt) | 1995-11-23 |
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