PT858324E - Processo de granulacao aquosa da claritromicina - Google Patents
Processo de granulacao aquosa da claritromicinaInfo
- Publication number
- PT858324E PT858324E PT96937699T PT96937699T PT858324E PT 858324 E PT858324 E PT 858324E PT 96937699 T PT96937699 T PT 96937699T PT 96937699 T PT96937699 T PT 96937699T PT 858324 E PT858324 E PT 858324E
- Authority
- PT
- Portugal
- Prior art keywords
- claritromycin
- aqueous granulation
- granulation process
- macrolide antibiotic
- carbomer
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US715095P | 1995-11-01 | 1995-11-01 | |
US08/722,288 US5919489A (en) | 1995-11-01 | 1996-10-09 | Process for aqueous granulation of clarithromycin |
PCT/US1996/016794 WO1997016174A1 (en) | 1995-11-01 | 1996-10-18 | Process for aqueous granulation of clarithromycin |
Publications (1)
Publication Number | Publication Date |
---|---|
PT858324E true PT858324E (pt) | 2003-10-31 |
Family
ID=26676595
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT96937699T PT858324E (pt) | 1995-11-01 | 1996-10-18 | Processo de granulacao aquosa da claritromicina |
Country Status (13)
Country | Link |
---|---|
US (1) | US5919489A (pt) |
EP (1) | EP0858324B1 (pt) |
JP (1) | JP4334015B2 (pt) |
KR (1) | KR100524202B1 (pt) |
AT (1) | ATE241963T1 (pt) |
AU (1) | AU706837B2 (pt) |
CA (1) | CA2235607C (pt) |
DE (1) | DE69628575T2 (pt) |
DK (1) | DK0858324T3 (pt) |
ES (1) | ES2200075T3 (pt) |
IL (1) | IL123571A (pt) |
PT (1) | PT858324E (pt) |
WO (1) | WO1997016174A1 (pt) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6551616B1 (en) | 1997-04-11 | 2003-04-22 | Abbott Laboratories | Extended release formulations of erythromycin derivatives |
US6010718A (en) * | 1997-04-11 | 2000-01-04 | Abbott Laboratories | Extended release formulations of erythromycin derivatives |
IN191239B (pt) | 1999-06-11 | 2003-10-11 | Ranbaxy Lab Ltd | |
CZ20014379A3 (cs) * | 1999-06-11 | 2002-08-14 | Ranbaxy Laboratories Limited | Kompozice k maskování chuti a způsob její přípravy |
AU1169601A (en) * | 1999-11-16 | 2001-05-30 | Ranbaxy Laboratories Limited | Taste masked oral compositions |
US6544555B2 (en) | 2000-02-24 | 2003-04-08 | Advancis Pharmaceutical Corp. | Antibiotic product, use and formulation thereof |
US6617436B2 (en) * | 2000-02-29 | 2003-09-09 | Teva Pharmaceutical Industries Ltd. | Processes for preparing clarithromycin and clarithromycin intermediate, essentially oxime-free clarithromycin, and pharmaceutical composition comprising the same |
WO2001072284A1 (en) * | 2000-03-28 | 2001-10-04 | Biochemie Gesellschaft M.B.H. | Granulated particles with masked taste |
US20020068078A1 (en) | 2000-10-13 | 2002-06-06 | Rudnic Edward M. | Antifungal product, use and formulation thereof |
DE10133546A1 (de) * | 2001-07-11 | 2003-03-06 | Petra Bastian | Mischkomplexe zur Maskierung bitter schmeckender Substanzen |
FR2827517B1 (fr) | 2001-07-23 | 2003-10-24 | Bioalliance Pharma | Systemes therapeutiques bioadhesifs a liberation prolongee |
DK1411899T3 (da) * | 2001-08-01 | 2009-06-02 | Novartis Ag | Smagsmaskerende sammensætning |
US20040043073A1 (en) * | 2002-06-14 | 2004-03-04 | Chih-Ming Chen | Pharmaceutical compositions for drugs having pH-dependent solubility |
US20060083759A1 (en) * | 2002-07-17 | 2006-04-20 | Aleksander Resman | Stabilization of the profile of release of active substances from a formulation |
EP1417958A1 (en) * | 2002-11-08 | 2004-05-12 | Pari GmbH | Wet granulation process |
PL1638529T3 (pl) * | 2003-06-16 | 2017-03-31 | Andrx Pharmaceuticals, Llc. | Kompozycja doustna o przedłużonym uwalnianiu |
EP1648407A4 (en) | 2003-07-21 | 2011-08-31 | Middlebrook Pharmaceuticals Inc | ANTIBIOTIC PRODUCT, CORRESPONDING USE AND FORMULATION |
WO2005009365A2 (en) | 2003-07-21 | 2005-02-03 | Advancis Pharmaceutical Corporation | Antibiotic product, use and formulation thereof |
JP2006528185A (ja) | 2003-07-21 | 2006-12-14 | アドバンシス ファーマスーティカル コーポレイション | 抗生物質製剤、その使用法及び作成方法 |
AU2004264939A1 (en) | 2003-08-11 | 2005-02-24 | Middlebrook Pharmaceuticals, Inc. | Robust pellet |
JP2007502294A (ja) | 2003-08-12 | 2007-02-08 | アドバンシス ファーマスーティカル コーポレイション | 抗生物質製剤、その使用法及び作成方法 |
CA2535780A1 (en) | 2003-08-29 | 2005-03-17 | Advancis Pharmaceuticals Corporation | Antibiotic product, use and formulation thereof |
AU2004273830B2 (en) | 2003-09-15 | 2011-03-24 | Shionogi, Inc. | Antibiotic product, use and formulation thereof |
ATE399536T1 (de) * | 2003-12-04 | 2008-07-15 | Pfizer Prod Inc | Verfahren zur herstellung von pharmazeutischen multiteilchenförmigen produkten |
CA2547773A1 (en) * | 2003-12-04 | 2005-06-16 | Pfizer Products Inc. | Spray-congeal process using an extruder for preparing multiparticulate azithromycin compositions containing preferably a poloxamer and a glyceride |
WO2005053652A1 (en) | 2003-12-04 | 2005-06-16 | Pfizer Products Inc. | Multiparticulate crystalline drug compositions containing a poloxamer and a glyceride |
WO2005053651A1 (en) * | 2003-12-04 | 2005-06-16 | Pfizer Products Inc. | Multiparticulate compositions with improved stability |
KR20060092281A (ko) * | 2003-12-04 | 2006-08-22 | 화이자 프로덕츠 인크. | 액체 기초 방법에 의한 아지트로마이신 복합입자 투여형 |
WO2005053639A2 (en) * | 2003-12-04 | 2005-06-16 | Pfizer Products Inc. | Controlled release multiparticulates formed with dissolution enhancers |
CA2549225A1 (en) * | 2003-12-04 | 2005-06-16 | Pfizer Products Inc. | Spray-congeal process using an extruder for preparing multiparticulate crystalline drug compositions containing preferably a poloxamer and a glyceride |
US6984403B2 (en) * | 2003-12-04 | 2006-01-10 | Pfizer Inc. | Azithromycin dosage forms with reduced side effects |
US7943585B2 (en) | 2003-12-22 | 2011-05-17 | Sandoz, Inc. | Extended release antibiotic composition |
AU2005269981A1 (en) | 2004-07-02 | 2006-02-09 | Bonck, John A | Tablet for pulsed delivery |
CN1883456B (zh) * | 2005-06-20 | 2010-12-15 | 常州市第四制药厂有限公司 | 掩味药物颗粒及其制备方法和用途 |
EP1904041A2 (en) * | 2005-07-07 | 2008-04-02 | Elan Pharma International Limited | Nanoparticulate clarithromycin formulations |
US20070048364A1 (en) * | 2005-08-04 | 2007-03-01 | Yingxu Peng | Free flowing granules containing carbomer |
US8778924B2 (en) | 2006-12-04 | 2014-07-15 | Shionogi Inc. | Modified release amoxicillin products |
US8357394B2 (en) | 2005-12-08 | 2013-01-22 | Shionogi Inc. | Compositions and methods for improved efficacy of penicillin-type antibiotics |
EP1837020A1 (en) | 2006-03-24 | 2007-09-26 | Bioalliance Pharma | Mucosal bioadhesive slow release carrier for delivering active principles |
US8299052B2 (en) | 2006-05-05 | 2012-10-30 | Shionogi Inc. | Pharmaceutical compositions and methods for improved bacterial eradication |
US20070286903A1 (en) * | 2006-06-13 | 2007-12-13 | Becicka Brian T | Composition and method for taste masking |
EP2030613A1 (en) * | 2007-08-17 | 2009-03-04 | Abbott GmbH & Co. KG | Preparation of compositions with essentially noncrystalline embedded macrolide antibiotics |
WO2012091039A1 (ja) * | 2010-12-27 | 2012-07-05 | 富田製薬株式会社 | 粒子状製剤 |
CN102813633A (zh) * | 2011-06-10 | 2012-12-12 | 塔科敏斯基制药厂波尔法合资公司 | 用湿法制粒制备包含大环内酯类抗生素的药物组合物的方法 |
RU2692469C1 (ru) * | 2018-06-25 | 2019-06-25 | ООО "Новые Антибиотики" | Лекарственное средство для лечения и предупреждения возникновения осложнений, связанных с химиотерапией и рентгенотерапией, а также состояний, связанных с повышенной проницаемостью кишки |
JP7442193B2 (ja) * | 2018-08-10 | 2024-03-04 | 日本臓器製薬株式会社 | 粒状組成物及びその製造方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4608278A (en) * | 1983-06-22 | 1986-08-26 | The Ohio State University Research Foundation | Small particule formation and encapsulation |
US4808411A (en) * | 1987-06-05 | 1989-02-28 | Abbott Laboratories | Antibiotic-polymer compositions |
-
1996
- 1996-10-09 US US08/722,288 patent/US5919489A/en not_active Expired - Lifetime
- 1996-10-18 JP JP51738497A patent/JP4334015B2/ja not_active Expired - Lifetime
- 1996-10-18 EP EP96937699A patent/EP0858324B1/en not_active Expired - Lifetime
- 1996-10-18 AU AU75176/96A patent/AU706837B2/en not_active Expired
- 1996-10-18 PT PT96937699T patent/PT858324E/pt unknown
- 1996-10-18 DK DK96937699T patent/DK0858324T3/da active
- 1996-10-18 KR KR1019980703233A patent/KR100524202B1/ko not_active IP Right Cessation
- 1996-10-18 IL IL12357196A patent/IL123571A/xx not_active IP Right Cessation
- 1996-10-18 CA CA002235607A patent/CA2235607C/en not_active Expired - Lifetime
- 1996-10-18 WO PCT/US1996/016794 patent/WO1997016174A1/en active IP Right Grant
- 1996-10-18 AT AT96937699T patent/ATE241963T1/de active
- 1996-10-18 ES ES96937699T patent/ES2200075T3/es not_active Expired - Lifetime
- 1996-10-18 DE DE69628575T patent/DE69628575T2/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0858324A1 (en) | 1998-08-19 |
AU706837B2 (en) | 1999-06-24 |
ES2200075T3 (es) | 2004-03-01 |
JP4334015B2 (ja) | 2009-09-16 |
IL123571A0 (en) | 1998-10-30 |
WO1997016174A1 (en) | 1997-05-09 |
EP0858324B1 (en) | 2003-06-04 |
DE69628575T2 (de) | 2004-04-29 |
DE69628575D1 (de) | 2003-07-10 |
KR19990067265A (ko) | 1999-08-16 |
CA2235607A1 (en) | 1997-05-09 |
AU7517696A (en) | 1997-05-22 |
JPH11514646A (ja) | 1999-12-14 |
MX9803480A (es) | 1998-09-30 |
KR100524202B1 (ko) | 2006-07-06 |
CA2235607C (en) | 2003-05-13 |
DK0858324T3 (da) | 2003-09-29 |
IL123571A (en) | 2005-07-25 |
ATE241963T1 (de) | 2003-06-15 |
US5919489A (en) | 1999-07-06 |
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