PT85149A - Process for the preparation oh human monoclonal antibodies to lymphadenopathy-associated virus - Google Patents
Process for the preparation oh human monoclonal antibodies to lymphadenopathy-associated virusInfo
- Publication number
- PT85149A PT85149A PT85149A PT8514987A PT85149A PT 85149 A PT85149 A PT 85149A PT 85149 A PT85149 A PT 85149A PT 8514987 A PT8514987 A PT 8514987A PT 85149 A PT85149 A PT 85149A
- Authority
- PT
- Portugal
- Prior art keywords
- monoclonal antibodies
- human monoclonal
- lav
- htlv
- iii
- Prior art date
Links
- 208000008771 Lymphadenopathy Diseases 0.000 title 1
- 241000700605 Viruses Species 0.000 title 1
- 208000018555 lymphatic system disease Diseases 0.000 title 1
- 230000000890 antigenic effect Effects 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- 239000012472 biological sample Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1036—Retroviridae, e.g. leukemia viruses
- C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
- C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/02—Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Oncology (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- AIDS & HIV (AREA)
- Physics & Mathematics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US87757986A | 1986-06-23 | 1986-06-23 |
Publications (2)
Publication Number | Publication Date |
---|---|
PT85149A true PT85149A (en) | 1987-07-01 |
PT85149B PT85149B (pt) | 1990-07-31 |
Family
ID=25370267
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT85149A PT85149B (pt) | 1986-06-23 | 1987-06-23 | Processo para a preparacao de anticorpos monoclonais humanos para o virus associado com linfadenopatia |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0251612B1 (pt) |
JP (1) | JP2626680B2 (pt) |
KR (1) | KR910001808B1 (pt) |
AT (1) | ATE103002T1 (pt) |
AU (1) | AU614714B2 (pt) |
CA (1) | CA1339830C (pt) |
DE (1) | DE3789333T2 (pt) |
DK (1) | DK169582B1 (pt) |
ES (1) | ES2050114T3 (pt) |
IE (1) | IE63109B1 (pt) |
IL (1) | IL82926A (pt) |
PT (1) | PT85149B (pt) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4879212A (en) * | 1986-04-02 | 1989-11-07 | United Biomedical Inc. | Peptide composition and method for the detection of antibodies to HTLV-III |
US5166050A (en) * | 1986-08-20 | 1992-11-24 | Bristol-Myers Squibb Company | Monoclonal antibodies and peptides useful in treating and diagnosing HIV infections |
NZ221440A (en) * | 1986-08-20 | 1991-11-26 | Genetic Systems Corp | Composition containing monoclonal antibodies/peptides useful in treating and diagnosing hiv infections |
FI872409A0 (fi) * | 1987-05-29 | 1987-05-29 | Labsystems Oy | Foerfarande foer detektering av hiv-1 motkroppar. |
EP0355140B1 (en) * | 1987-11-13 | 1996-03-20 | KATINGER, Hermann | Human monoclonal anti-hiv-i-antibodies |
IL88963A (en) * | 1988-01-27 | 1996-05-14 | Iaf Biochem Int | Circular synthetic peptides and their mixtures for the detection of VIH antibodies and for the formation of vaccines |
US5298419A (en) * | 1988-03-31 | 1994-03-29 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Human hybridomas and monoclonal antibodies which bind both gp41 and gp120 envelope proteins of human immunodeficiency virus |
CA1339775C (en) * | 1988-06-10 | 1998-03-24 | Shuzo Matsushita | Antibody 0.5b to hiv-i gp 120 modified with toxic substance |
JPH0292298A (ja) * | 1988-09-30 | 1990-04-03 | Olympus Optical Co Ltd | Hiv構成蛋白に対するモノクローナル抗体 |
EP0418347A4 (en) * | 1989-02-28 | 1994-12-14 | Univ New York | Human monoclonal antibodies to human immunodeficiency virus |
US5731189A (en) * | 1989-02-28 | 1998-03-24 | New York University | Human monoclonal antibodies to human immunodeficiency virus |
WO1990010457A1 (en) * | 1989-03-14 | 1990-09-20 | New York University | Method of treating hiv infections using immunotoxins |
US6248574B1 (en) | 1989-12-13 | 2001-06-19 | Avigdor Shaffermann | Polypeptides selectively reactive with antibodies against human immunodeficiency virus and vaccines comprising the polypeptides |
FR2657017B1 (fr) * | 1990-01-16 | 1995-08-18 | Clonatec Sa | Peptides derivant de la glycoproteine d'enveloppe du virus-hiv-1, leurs applications a la detection d'une infection due a ce virus et a la vaccination contre le sida. |
ATE164853T1 (de) * | 1990-01-16 | 1998-04-15 | Orgenics Ltd | Peptide, von virus-hiv-hüllen-glycoproteinen abstammend, deren verwendung zum nachweis einer infektion dieser viren und für die impfung gegen aids |
DE19809785C2 (de) * | 1998-03-08 | 2000-02-10 | Wolfgang Bergter | Radioimmunpharmakon zur Behandlung der HIV-1-Infektion |
US6680209B1 (en) * | 1999-12-06 | 2004-01-20 | Biosite, Incorporated | Human antibodies as diagnostic reagents |
WO2005115992A1 (en) | 2004-05-23 | 2005-12-08 | Housey Pharmaceuticals, Inc. | Theramutein modulators |
US8431110B2 (en) | 2005-05-23 | 2013-04-30 | Hmi Medical Innovations, Llc. | Compounds and method of identifying, synthesizing, optimizing and profiling protein modulators |
JP2019509046A (ja) | 2015-12-05 | 2019-04-04 | サントル オスピタリエ ユニヴェルシテール ヴォドアCentre Hospitalier Universitaire Vaudois | Hiv結合剤 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4520113A (en) | 1984-04-23 | 1985-05-28 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Serological detection of antibodies to HTLV-III in sera of patients with AIDS and pre-AIDS conditions |
US9328391B1 (en) * | 1984-08-22 | 2016-05-03 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Cloning and expression of HIV-1 DNA |
IE64785B1 (en) * | 1985-04-08 | 1995-09-06 | Genetic Systems Corp | Expression of immunologically reactive viral proteins |
FR2580177B2 (fr) * | 1985-04-15 | 1989-06-02 | Pasteur Institut | Antigenes apparentes a la glycoproteine d'enveloppe du virus du sida, notamment precurseurs de cette glycoproteine, procedes d'obtention de ces antigenes et moyens mis en oeuvre dans ces procedes, applications de ces antigenes a la preparation de compositions immunogenes ou pour le diagnostic du sida ou des affections qui lui sont apparentees |
WO1986006414A1 (en) * | 1985-04-29 | 1986-11-06 | Genetic Systems Corporation | Synthetic antigens for the detection of aids-related disease |
JP2702911B2 (ja) * | 1985-09-11 | 1998-01-26 | ユナイテツド・バイオメデイカル・インコ−ポレ−テツド | 合成ペプチド、並びにそれを用いたエイズおよびプリ・エイズの検出方法 |
US4772547A (en) * | 1986-02-03 | 1988-09-20 | Hoffmann-La Roche Inc. | HTLV-III envelope peptides |
US4904581A (en) * | 1986-05-06 | 1990-02-27 | Epitope, Inc. | Method of detecting AIDS virus infection |
AU8127187A (en) * | 1986-12-03 | 1988-06-09 | Ici Australia Operations Proprietary Limited | Mine roof supporting element |
-
1987
- 1987-06-15 IE IE158787A patent/IE63109B1/en not_active IP Right Cessation
- 1987-06-15 DK DK304087A patent/DK169582B1/da active
- 1987-06-19 IL IL82926A patent/IL82926A/xx not_active IP Right Cessation
- 1987-06-19 AU AU74512/87A patent/AU614714B2/en not_active Ceased
- 1987-06-22 DE DE3789333T patent/DE3789333T2/de not_active Expired - Fee Related
- 1987-06-22 KR KR1019870006344A patent/KR910001808B1/ko not_active IP Right Cessation
- 1987-06-22 JP JP62155247A patent/JP2626680B2/ja not_active Expired - Lifetime
- 1987-06-22 AT AT87305505T patent/ATE103002T1/de not_active IP Right Cessation
- 1987-06-22 ES ES87305505T patent/ES2050114T3/es not_active Expired - Lifetime
- 1987-06-22 CA CA000540255A patent/CA1339830C/en not_active Expired - Fee Related
- 1987-06-22 EP EP87305505A patent/EP0251612B1/en not_active Expired - Lifetime
- 1987-06-23 PT PT85149A patent/PT85149B/pt not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
IL82926A (en) | 1991-07-18 |
DK169582B1 (da) | 1994-12-12 |
IE871587L (en) | 1987-12-23 |
ES2050114T3 (es) | 1994-05-16 |
IL82926A0 (en) | 1987-12-20 |
JPS63107998A (ja) | 1988-05-12 |
DK304087A (da) | 1987-12-24 |
AU7451287A (en) | 1987-12-24 |
DK304087D0 (da) | 1987-06-15 |
IE63109B1 (en) | 1995-03-22 |
KR910001808B1 (ko) | 1991-03-26 |
CA1339830C (en) | 1998-04-21 |
EP0251612A3 (en) | 1990-05-23 |
PT85149B (pt) | 1990-07-31 |
EP0251612A2 (en) | 1988-01-07 |
EP0251612B1 (en) | 1994-03-16 |
DE3789333T2 (de) | 1994-07-07 |
DE3789333D1 (de) | 1994-04-21 |
JP2626680B2 (ja) | 1997-07-02 |
ATE103002T1 (de) | 1994-04-15 |
AU614714B2 (en) | 1991-09-12 |
KR880000585A (ko) | 1988-03-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19990731 |