DE3789333D1 - Menschlicher monoklonaler Antikörper gegen Lymphadenopathie assozierten Virus. - Google Patents

Menschlicher monoklonaler Antikörper gegen Lymphadenopathie assozierten Virus.

Info

Publication number
DE3789333D1
DE3789333D1 DE87305505T DE3789333T DE3789333D1 DE 3789333 D1 DE3789333 D1 DE 3789333D1 DE 87305505 T DE87305505 T DE 87305505T DE 3789333 T DE3789333 T DE 3789333T DE 3789333 D1 DE3789333 D1 DE 3789333D1
Authority
DE
Germany
Prior art keywords
human monoclonal
lav
htlv
iii
monoclonal antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE87305505T
Other languages
English (en)
Other versions
DE3789333T2 (de
Inventor
Janela Mcclure
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of DE3789333D1 publication Critical patent/DE3789333D1/de
Publication of DE3789333T2 publication Critical patent/DE3789333T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036—Retroviridae, e.g. leukemia viruses
    • C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/02—Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • AIDS & HIV (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE3789333T 1986-06-23 1987-06-22 Menschlicher monoklonaler Antikörper gegen Lymphadenopathie assozierten Virus. Expired - Fee Related DE3789333T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US87757986A 1986-06-23 1986-06-23

Publications (2)

Publication Number Publication Date
DE3789333D1 true DE3789333D1 (de) 1994-04-21
DE3789333T2 DE3789333T2 (de) 1994-07-07

Family

ID=25370267

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3789333T Expired - Fee Related DE3789333T2 (de) 1986-06-23 1987-06-22 Menschlicher monoklonaler Antikörper gegen Lymphadenopathie assozierten Virus.

Country Status (12)

Country Link
EP (1) EP0251612B1 (de)
JP (1) JP2626680B2 (de)
KR (1) KR910001808B1 (de)
AT (1) ATE103002T1 (de)
AU (1) AU614714B2 (de)
CA (1) CA1339830C (de)
DE (1) DE3789333T2 (de)
DK (1) DK169582B1 (de)
ES (1) ES2050114T3 (de)
IE (1) IE63109B1 (de)
IL (1) IL82926A (de)
PT (1) PT85149B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4879212A (en) * 1986-04-02 1989-11-07 United Biomedical Inc. Peptide composition and method for the detection of antibodies to HTLV-III
US5166050A (en) * 1986-08-20 1992-11-24 Bristol-Myers Squibb Company Monoclonal antibodies and peptides useful in treating and diagnosing HIV infections
NZ221440A (en) * 1986-08-20 1991-11-26 Genetic Systems Corp Composition containing monoclonal antibodies/peptides useful in treating and diagnosing hiv infections
FI872409A0 (fi) * 1987-05-29 1987-05-29 Labsystems Oy Foerfarande foer detektering av hiv-1 motkroppar.
EP0355140B1 (de) * 1987-11-13 1996-03-20 KATINGER, Hermann Monoklonale menschliche antikörper gegen hiv-i
AU629528B2 (en) * 1988-01-27 1992-10-08 Biochem Pharma Inc. Synthetic peptides and mixtures thereof for detecting hiv antibodies
US5298419A (en) * 1988-03-31 1994-03-29 The Arizona Board Of Regents On Behalf Of The University Of Arizona Human hybridomas and monoclonal antibodies which bind both gp41 and gp120 envelope proteins of human immunodeficiency virus
CA1339775C (en) * 1988-06-10 1998-03-24 Shuzo Matsushita Antibody 0.5b to hiv-i gp 120 modified with toxic substance
JPH0292298A (ja) * 1988-09-30 1990-04-03 Olympus Optical Co Ltd Ｈｉｖ構成蛋白に対するモノクローナル抗体
US5731189A (en) * 1989-02-28 1998-03-24 New York University Human monoclonal antibodies to human immunodeficiency virus
CA2028121A1 (en) * 1989-02-28 1990-08-29 Susan Zolla-Pazner Human monoclonal antibodies to human immunodeficiency virus
WO1990010457A1 (en) * 1989-03-14 1990-09-20 New York University Method of treating hiv infections using immunotoxins
US6248574B1 (en) 1989-12-13 2001-06-19 Avigdor Shaffermann Polypeptides selectively reactive with antibodies against human immunodeficiency virus and vaccines comprising the polypeptides
EP0438332B1 (de) * 1990-01-16 1998-04-08 Orgenics Ltd. Peptide, von Virus-HIV-Hüllen-Glycoproteinen abstammend, deren Verwendung zum Nachweis einer Infektion dieser Viren und für die Impfung gegen AIDS
FR2657017B1 (fr) * 1990-01-16 1995-08-18 Clonatec Sa Peptides derivant de la glycoproteine d'enveloppe du virus-hiv-1, leurs applications a la detection d'une infection due a ce virus et a la vaccination contre le sida.
DE19809785C2 (de) * 1998-03-08 2000-02-10 Wolfgang Bergter Radioimmunpharmakon zur Behandlung der HIV-1-Infektion
US6680209B1 (en) 1999-12-06 2004-01-20 Biosite, Incorporated Human antibodies as diagnostic reagents
EP1751115A4 (de) 2004-05-23 2010-10-20 Gerard M Housey Theramuteinmodulatoren
US8431110B2 (en) 2005-05-23 2013-04-30 Hmi Medical Innovations, Llc. Compounds and method of identifying, synthesizing, optimizing and profiling protein modulators
CN108779168A (zh) 2015-12-05 2018-11-09 沃迪奥斯大学医院中心 Hiv结合剂

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4520113A (en) * 1984-04-23 1985-05-28 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Serological detection of antibodies to HTLV-III in sera of patients with AIDS and pre-AIDS conditions
US9328391B1 (en) * 1984-08-22 2016-05-03 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Cloning and expression of HIV-1 DNA
IE64785B1 (en) * 1985-04-08 1995-09-06 Genetic Systems Corp Expression of immunologically reactive viral proteins
FR2580177B2 (fr) * 1985-04-15 1989-06-02 Pasteur Institut Antigenes apparentes a la glycoproteine d'enveloppe du virus du sida, notamment precurseurs de cette glycoproteine, procedes d'obtention de ces antigenes et moyens mis en oeuvre dans ces procedes, applications de ces antigenes a la preparation de compositions immunogenes ou pour le diagnostic du sida ou des affections qui lui sont apparentees
EP0220273B2 (de) * 1985-04-29 2007-01-17 Bio-Rad Laboratories, Inc. Synthetische antigene zum nachweis von aids
JP2702911B2 (ja) * 1985-09-11 1998-01-26 ユナイテツド・バイオメデイカル・インコ−ポレ−テツド 合成ペプチド、並びにそれを用いたエイズおよびプリ・エイズの検出方法
US4772547A (en) * 1986-02-03 1988-09-20 Hoffmann-La Roche Inc. HTLV-III envelope peptides
US4904581A (en) * 1986-05-06 1990-02-27 Epitope, Inc. Method of detecting AIDS virus infection
AU8127187A (en) * 1986-12-03 1988-06-09 Ici Australia Operations Proprietary Limited Mine roof supporting element

Also Published As

Publication number Publication date
IE871587L (en) 1987-12-23
DE3789333T2 (de) 1994-07-07
ATE103002T1 (de) 1994-04-15
KR910001808B1 (ko) 1991-03-26
AU7451287A (en) 1987-12-24
AU614714B2 (en) 1991-09-12
PT85149B (pt) 1990-07-31
KR880000585A (ko) 1988-03-28
EP0251612B1 (de) 1994-03-16
CA1339830C (en) 1998-04-21
IL82926A (en) 1991-07-18
IE63109B1 (en) 1995-03-22
DK304087D0 (da) 1987-06-15
IL82926A0 (en) 1987-12-20
EP0251612A3 (en) 1990-05-23
DK169582B1 (da) 1994-12-12
JPS63107998A (ja) 1988-05-12
EP0251612A2 (de) 1988-01-07
JP2626680B2 (ja) 1997-07-02
PT85149A (en) 1987-07-01
DK304087A (da) 1987-12-24
ES2050114T3 (es) 1994-05-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee