PT84332B - Processo para a preparacao de um novo derivado triciclico denominado acido 5-"{3-cloro-6-metil-5,5-dioxo-6,11-dihidro-(c,f)-dibenzo-11-tiazepina-(1,2)-il}-amino"-pentanoico - Google Patents
Processo para a preparacao de um novo derivado triciclico denominado acido 5-"{3-cloro-6-metil-5,5-dioxo-6,11-dihidro-(c,f)-dibenzo-11-tiazepina-(1,2)-il}-amino"-pentanoicoInfo
- Publication number
- PT84332B PT84332B PT84332A PT8433287A PT84332B PT 84332 B PT84332 B PT 84332B PT 84332 A PT84332 A PT 84332A PT 8433287 A PT8433287 A PT 8433287A PT 84332 B PT84332 B PT 84332B
- Authority
- PT
- Portugal
- Prior art keywords
- derived
- acid
- dibenzo
- dioxo
- dihydro
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- BYPYVXCZPZLHBO-UHFFFAOYSA-N 5-[(3-chloro-6-methyl-5,5-dioxo-11h-benzo[c][2,1]benzothiazepin-11-yl)azaniumyl]pentanoate Chemical compound O=S1(=O)N(C)C2=CC=CC=C2C(NCCCCC(O)=O)C2=CC=C(Cl)C=C21 BYPYVXCZPZLHBO-UHFFFAOYSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8602399A FR2594827B1 (fr) | 1986-02-21 | 1986-02-21 | Nouveau derive tricyclique denomme acide ((chloro-3 methyl-6 dioxo-5,5 dihydro-6, 11 dibenzo (c,f) thiazepine (1,2) yl-11 amino)-5 pentazoique, son procede de preparation et les compositions pharmaceutiques qui le contiennent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT84332A PT84332A (fr) | 1987-03-01 |
| PT84332B true PT84332B (pt) | 1989-09-14 |
Family
ID=9332386
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT84332A PT84332B (pt) | 1986-02-21 | 1987-02-20 | Processo para a preparacao de um novo derivado triciclico denominado acido 5-"{3-cloro-6-metil-5,5-dioxo-6,11-dihidro-(c,f)-dibenzo-11-tiazepina-(1,2)-il}-amino"-pentanoico |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4766114A (en, 2012) |
| EP (1) | EP0239436B1 (en, 2012) |
| JP (1) | JPS62198672A (en, 2012) |
| AT (1) | ATE53995T1 (en, 2012) |
| CA (1) | CA1282781C (en, 2012) |
| DE (1) | DE3763311D1 (en, 2012) |
| DK (1) | DK88087A (en, 2012) |
| ES (1) | ES2004097A6 (en, 2012) |
| FR (1) | FR2594827B1 (en, 2012) |
| GR (1) | GR870285B (en, 2012) |
| IE (1) | IE59468B1 (en, 2012) |
| PT (1) | PT84332B (en, 2012) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2040629B1 (es) * | 1991-12-18 | 1994-06-16 | Consejo Superior Investigacion | Procedimiento de obtencion de derivados triciclicos de la benzotiazepina farmacologicamente activos. |
| US5716949A (en) * | 1995-04-07 | 1998-02-10 | Novo Nordisk A/S | Heterocyclic compounds |
| US6683072B1 (en) | 2003-02-04 | 2004-01-27 | Vela Pharmaceuticals, Inc. | Compositions and methods for treatment of irritable bowel syndrome and nonulcer dyspepsia |
| US20050227961A1 (en) * | 2004-04-08 | 2005-10-13 | Vela Pharmaceuticals, Inc. | Compositions and methods for treatment of neuropathic pain, fibromyalgia and chronic fatigue syndrome |
| JP2010520298A (ja) * | 2007-03-05 | 2010-06-10 | トランスフオーム・フアーマシユーチカルズ・インコーポレーテツド | ７−［（３−クロロ−６，１１−ジヒドロ−６−メチルジベンゾ［ｃ，ｆ］［１，２］チアゼピン−１１−イル）アミノ］ヘプタン酸Ｓ，Ｓ−ジオキシドの多形相ならびにそれらの製造及び使用方法 |
| US9314469B2 (en) | 2008-05-05 | 2016-04-19 | Tonix Pharma Holdings Limited | Method for treating neurocognitive dysfunction |
| GB201208315D0 (en) | 2012-05-11 | 2012-06-27 | Numedicus Ltd | Pharmaceutical methods and compositions |
| AU2015229258B2 (en) * | 2014-03-12 | 2020-01-30 | The Trustees Of Columbia University In The City Of New York | A new class of Mu-Opioid receptor agonists |
| CN108135866A (zh) | 2015-09-16 | 2018-06-08 | 哥伦比亚大学董事会 | 羧基二芳基硫氮杂胺作为μ-阿片受体激动剂 |
| WO2022074588A1 (en) * | 2020-10-06 | 2022-04-14 | Kures, Inc. | Carboxylic diarylthiazepineamines and uses therefor |
| WO2022074587A1 (en) * | 2020-10-06 | 2022-04-14 | Kures, Inc. | Mu-opioid receptor agonists and uses therefor |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1269551A (en) * | 1969-03-27 | 1972-04-06 | Science Union & Cie | New tricyclic derivatives and process for their manufacture |
| US3821249A (en) * | 1970-03-13 | 1974-06-28 | En Nom Collectif Science Union | Dibenzothiazefin derivatives |
-
1986
- 1986-02-21 FR FR8602399A patent/FR2594827B1/fr not_active Expired
-
1987
- 1987-02-19 ES ES8700429A patent/ES2004097A6/es not_active Expired
- 1987-02-20 JP JP62037711A patent/JPS62198672A/ja active Granted
- 1987-02-20 IE IE42787A patent/IE59468B1/en not_active IP Right Cessation
- 1987-02-20 CA CA000530291A patent/CA1282781C/fr not_active Expired - Lifetime
- 1987-02-20 GR GR870285A patent/GR870285B/el unknown
- 1987-02-20 DK DK088087A patent/DK88087A/da unknown
- 1987-02-20 AT AT87400371T patent/ATE53995T1/de active
- 1987-02-20 US US07/017,237 patent/US4766114A/en not_active Expired - Fee Related
- 1987-02-20 EP EP87400371A patent/EP0239436B1/fr not_active Expired - Lifetime
- 1987-02-20 DE DE8787400371T patent/DE3763311D1/de not_active Expired - Lifetime
- 1987-02-20 PT PT84332A patent/PT84332B/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2594827A1 (fr) | 1987-08-28 |
| JPH0378858B2 (en, 2012) | 1991-12-17 |
| US4766114A (en) | 1988-08-23 |
| FR2594827B1 (fr) | 1988-05-20 |
| EP0239436B1 (fr) | 1990-06-20 |
| DK88087D0 (da) | 1987-02-20 |
| ES2004097A6 (es) | 1988-12-01 |
| IE59468B1 (en) | 1994-03-09 |
| JPS62198672A (ja) | 1987-09-02 |
| DE3763311D1 (de) | 1990-07-26 |
| IE870427L (en) | 1987-08-21 |
| ATE53995T1 (de) | 1990-07-15 |
| GR870285B (en) | 1987-06-30 |
| EP0239436A1 (fr) | 1987-09-30 |
| DK88087A (da) | 1987-08-22 |
| CA1282781C (fr) | 1991-04-09 |
| PT84332A (fr) | 1987-03-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19970831 |