PT84332B - Processo para a preparacao de um novo derivado triciclico denominado acido 5-"{3-cloro-6-metil-5,5-dioxo-6,11-dihidro-(c,f)-dibenzo-11-tiazepina-(1,2)-il}-amino"-pentanoico - Google Patents

Processo para a preparacao de um novo derivado triciclico denominado acido 5-"{3-cloro-6-metil-5,5-dioxo-6,11-dihidro-(c,f)-dibenzo-11-tiazepina-(1,2)-il}-amino"-pentanoico

Info

Publication number
PT84332B
PT84332B PT84332A PT8433287A PT84332B PT 84332 B PT84332 B PT 84332B PT 84332 A PT84332 A PT 84332A PT 8433287 A PT8433287 A PT 8433287A PT 84332 B PT84332 B PT 84332B
Authority
PT
Portugal
Prior art keywords
derived
acid
dibenzo
dioxo
dihydro
Prior art date
Application number
PT84332A
Other languages
English (en)
Other versions
PT84332A (fr
Inventor
Charles Malen
Jean-Claude Poignant
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of PT84332A publication Critical patent/PT84332A/pt
Publication of PT84332B publication Critical patent/PT84332B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
PT84332A 1986-02-21 1987-02-20 Processo para a preparacao de um novo derivado triciclico denominado acido 5-"{3-cloro-6-metil-5,5-dioxo-6,11-dihidro-(c,f)-dibenzo-11-tiazepina-(1,2)-il}-amino"-pentanoico PT84332B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8602399A FR2594827B1 (fr) 1986-02-21 1986-02-21 Nouveau derive tricyclique denomme acide ((chloro-3 methyl-6 dioxo-5,5 dihydro-6, 11 dibenzo (c,f) thiazepine (1,2) yl-11 amino)-5 pentazoique, son procede de preparation et les compositions pharmaceutiques qui le contiennent

Publications (2)

Publication Number Publication Date
PT84332A PT84332A (fr) 1987-03-01
PT84332B true PT84332B (pt) 1989-09-14

Family

ID=9332386

Family Applications (1)

Application Number Title Priority Date Filing Date
PT84332A PT84332B (pt) 1986-02-21 1987-02-20 Processo para a preparacao de um novo derivado triciclico denominado acido 5-"{3-cloro-6-metil-5,5-dioxo-6,11-dihidro-(c,f)-dibenzo-11-tiazepina-(1,2)-il}-amino"-pentanoico

Country Status (12)

Country Link
US (1) US4766114A (pt)
EP (1) EP0239436B1 (pt)
JP (1) JPS62198672A (pt)
AT (1) ATE53995T1 (pt)
CA (1) CA1282781C (pt)
DE (1) DE3763311D1 (pt)
DK (1) DK88087A (pt)
ES (1) ES2004097A6 (pt)
FR (1) FR2594827B1 (pt)
GR (1) GR870285B (pt)
IE (1) IE59468B1 (pt)
PT (1) PT84332B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2040629B1 (es) * 1991-12-18 1994-06-16 Consejo Superior Investigacion Procedimiento de obtencion de derivados triciclicos de la benzotiazepina farmacologicamente activos.
US5716949A (en) * 1995-04-07 1998-02-10 Novo Nordisk A/S Heterocyclic compounds
US6683072B1 (en) 2003-02-04 2004-01-27 Vela Pharmaceuticals, Inc. Compositions and methods for treatment of irritable bowel syndrome and nonulcer dyspepsia
US20050227961A1 (en) * 2004-04-08 2005-10-13 Vela Pharmaceuticals, Inc. Compositions and methods for treatment of neuropathic pain, fibromyalgia and chronic fatigue syndrome
WO2008109577A1 (en) * 2007-03-05 2008-09-12 Transform Pharmaceuticals, Inc. Polymorphs of 7-[(3-chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic acid s,s dioxide and methods of making and using the same
US9314469B2 (en) 2008-05-05 2016-04-19 Tonix Pharma Holdings Limited Method for treating neurocognitive dysfunction
GB201208315D0 (en) 2012-05-11 2012-06-27 Numedicus Ltd Pharmaceutical methods and compositions
JP6557674B2 (ja) * 2014-03-12 2019-08-07 ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨーク 新規クラスのミュー−オピオイド受容体アゴニスト
US10844027B2 (en) 2015-09-16 2020-11-24 The Trustees Of Columbia University In The City Of New York Carboxylic diarylthiazepineamines as mu-opioid receptor agonists
US20240092802A1 (en) * 2020-10-06 2024-03-21 Kures, Inc. Mu-opioid receptor agonists and uses therefor
WO2022074588A1 (en) * 2020-10-06 2022-04-14 Kures, Inc. Carboxylic diarylthiazepineamines and uses therefor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1269551A (en) * 1969-03-27 1972-04-06 Science Union & Cie New tricyclic derivatives and process for their manufacture
US3821249A (en) * 1970-03-13 1974-06-28 En Nom Collectif Science Union Dibenzothiazefin derivatives

Also Published As

Publication number Publication date
JPH0378858B2 (pt) 1991-12-17
DE3763311D1 (de) 1990-07-26
DK88087D0 (da) 1987-02-20
FR2594827B1 (fr) 1988-05-20
US4766114A (en) 1988-08-23
FR2594827A1 (fr) 1987-08-28
ATE53995T1 (de) 1990-07-15
JPS62198672A (ja) 1987-09-02
GR870285B (en) 1987-06-30
IE870427L (en) 1987-08-21
EP0239436B1 (fr) 1990-06-20
ES2004097A6 (es) 1988-12-01
CA1282781C (fr) 1991-04-09
IE59468B1 (en) 1994-03-09
EP0239436A1 (fr) 1987-09-30
DK88087A (da) 1987-08-22
PT84332A (fr) 1987-03-01

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Effective date: 19970831