PT842279E - VíRUS AUXILIARES PARA A PREPARACAO DE VECTORES VIRAIS RECOMBINANTES - Google Patents

VíRUS AUXILIARES PARA A PREPARACAO DE VECTORES VIRAIS RECOMBINANTES

Info

Publication number
PT842279E
PT842279E PT96927107T PT96927107T PT842279E PT 842279 E PT842279 E PT 842279E PT 96927107 T PT96927107 T PT 96927107T PT 96927107 T PT96927107 T PT 96927107T PT 842279 E PT842279 E PT 842279E
Authority
PT
Portugal
Prior art keywords
preparation
recombinant virus
virus vectors
auxiliary viruses
recombinase
Prior art date
Application number
PT96927107T
Other languages
English (en)
Inventor
Majid Mehtali
Monika Luska
Original Assignee
Transgene Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transgene Sa filed Critical Transgene Sa
Publication of PT842279E publication Critical patent/PT842279E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10351—Methods of production or purification of viral material
    • C12N2710/10352—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/30—Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT96927107T 1995-07-31 1996-07-30 VíRUS AUXILIARES PARA A PREPARACAO DE VECTORES VIRAIS RECOMBINANTES PT842279E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9509289A FR2737501B1 (fr) 1995-07-31 1995-07-31 Nouveaux virus auxiliaires pour la preparation de vecteurs viraux recombinants

Publications (1)

Publication Number Publication Date
PT842279E true PT842279E (pt) 2002-04-29

Family

ID=9481555

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96927107T PT842279E (pt) 1995-07-31 1996-07-30 VíRUS AUXILIARES PARA A PREPARACAO DE VECTORES VIRAIS RECOMBINANTES

Country Status (12)

Country Link
US (3) US6066478A (pt)
EP (2) EP0842279B1 (pt)
JP (1) JP3416143B2 (pt)
AT (1) ATE207959T1 (pt)
AU (1) AU715487B2 (pt)
CA (1) CA2225551A1 (pt)
DE (1) DE69616559T2 (pt)
DK (1) DK0842279T3 (pt)
ES (1) ES2164910T3 (pt)
FR (1) FR2737501B1 (pt)
PT (1) PT842279E (pt)
WO (1) WO1997005255A2 (pt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020136708A1 (en) 1993-06-24 2002-09-26 Graham Frank L. System for production of helper dependent adenovirus vectors based on use of endonucleases
US7045347B2 (en) 1993-06-24 2006-05-16 Advec, Inc. Helper dependent adenovirus vectors based on integrase family site-specific recombinases
US20020146392A1 (en) * 1993-06-24 2002-10-10 Frank L. Graham Helper dependent adenovirus vectors based on site-specific recombinases
JP4216350B2 (ja) * 1994-09-19 2009-01-28 大日本住友製薬株式会社 動物細胞感染用の組換えｄｎａウイルスベクター
AU2004201152B2 (en) * 1995-06-07 2007-03-08 Advec, Inc. Helper Dependent Adenovirus Vectors Based on Site-specific Recombinases
US6783980B2 (en) 1995-06-15 2004-08-31 Crucell Holland B.V. Packaging systems for human recombinant adenovirus to be used in gene therapy
US6265212B1 (en) 1995-06-15 2001-07-24 Introgene B.V. Packaging systems for human recombinant adenovirus to be used in gene therapy
ATE445705T1 (de) 1995-06-15 2009-10-15 Crucell Holland Bv Verpackungssysteme für humane rekombinante adenoviren zur gentherapie
AU752284B2 (en) * 1998-02-17 2002-09-12 Genzyme Corporation Methods for pseudoadenoviral vector production
AUPP249298A0 (en) * 1998-03-20 1998-04-23 Ag-Gene Australia Limited Synthetic genes and genetic constructs comprising same I
GB2353282C (en) * 1998-03-20 2013-02-27 State Queensland Primary Ind Control of gene expression
US20040214330A1 (en) * 1999-04-07 2004-10-28 Waterhouse Peter Michael Methods and means for obtaining modified phenotypes
US8598332B1 (en) * 1998-04-08 2013-12-03 Bayer Cropscience N.V. Methods and means for obtaining modified phenotypes
US6670188B1 (en) 1998-04-24 2003-12-30 Crucell Holland B.V. Packaging systems for human recombinant adenovirus to be used in gene therapy
DK1131087T4 (da) * 1998-11-13 2009-08-03 Stryker Corp Lindring af prostatacancersymptomer
US6423885B1 (en) 1999-08-13 2002-07-23 Commonwealth Scientific And Industrial Research Organization (Csiro) Methods for obtaining modified phenotypes in plant cells
JP2004532039A (ja) * 2001-03-26 2004-10-21 ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ ヘルパー依存性アデノウイルスベクター系およびその系の使用方法
DE10159167A1 (de) * 2001-12-03 2003-10-02 Guenter Cichon Expressionssystem
DE60329747D1 (de) * 2002-05-02 2009-12-03 Univ Rochester Vektoren mit beiden isoformen von beta-hexosaminidase
US20050101961A1 (en) * 2003-11-12 2005-05-12 Huebner Randall J. Bone screws
JP2006500012A (ja) * 2002-07-31 2006-01-05 ヌクレオニクス インコーポレーティッド 二本鎖ｒｎａの構造および構築物、並びにその作製法および使用法
US20040203133A1 (en) * 2003-01-07 2004-10-14 Anja Ehrhardt Helper dependent adenoviral vector system and methods for using the same
US7686839B2 (en) * 2005-01-26 2010-03-30 Lumitex, Inc. Phototherapy treatment devices for applying area lighting to a wound
ES2337973B8 (es) * 2008-05-16 2011-07-21 Proyecto De Biomedicina Cima, S.L. Adenovirus auxiliares auto-inactivantes para la produccion de adenovirus recombinantes de alta capacidad.
KR20130115105A (ko) * 2010-06-02 2013-10-21 박스터 헬쓰케어 에스에이 Rna 바이러스를 생산하는 방법 및 헬퍼 바이러스

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0300422B1 (en) * 1987-07-21 1992-12-02 The Du Pont Merck Pharmaceutical Company An improved method for preparing stable and viable recombinant animal cell viral vectors
US5173414A (en) * 1990-10-30 1992-12-22 Applied Immune Sciences, Inc. Production of recombinant adeno-associated virus vectors
US5919676A (en) * 1993-06-24 1999-07-06 Advec, Inc. Adenoviral vector system comprising Cre-loxP recombination
FR2707664B1 (fr) * 1993-07-13 1995-09-29 Centre Nat Rech Scient Vecteurs viraux et utilisation en thérapie génique.
JP3770333B2 (ja) * 1995-03-15 2006-04-26 大日本住友製薬株式会社 組換えｄｎａウイルスおよびその製造方法

Also Published As

Publication number Publication date
FR2737501B1 (fr) 1997-10-24
JP3416143B2 (ja) 2003-06-16
AU6704496A (en) 1997-02-26
ATE207959T1 (de) 2001-11-15
AU715487B2 (en) 2000-02-03
EP1132478A3 (fr) 2002-09-04
WO1997005255A3 (fr) 1997-03-06
EP0842279A2 (fr) 1998-05-20
EP0842279B1 (fr) 2001-10-31
DE69616559D1 (de) 2001-12-06
US20020072120A1 (en) 2002-06-13
EP1132478A2 (fr) 2001-09-12
WO1997005255A2 (fr) 1997-02-13
JPH11510049A (ja) 1999-09-07
US6066478A (en) 2000-05-23
DE69616559T2 (de) 2002-06-27
FR2737501A1 (fr) 1997-02-07
ES2164910T3 (es) 2002-03-01
US6350575B1 (en) 2002-02-26
CA2225551A1 (fr) 1997-02-13
DK0842279T3 (da) 2002-02-25

Similar Documents

Publication Publication Date Title
PT842279E (pt) VíRUS AUXILIARES PARA A PREPARACAO DE VECTORES VIRAIS RECOMBINANTES
CA2157063A1 (en) Recombinant dna viral vector for transfecting animal cells
CA2236968A1 (en) Accessory functions for use in recombinant aav virion production
PL333070A1 (en) Infectious clones of rna viruses and vaccines based on them
ATE79649T1 (de) Herpes simplex-virus als vektor.
ATE358732T1 (de) Anti-virale vektoren
EP1394259A3 (en) Recombinant infectious non-segmented negative strand RNA virus
FI961146A (fi) Adenoassosioituja virusliposomeja ja niihin liittyviä menetelmiä
CA2127541A1 (en) Recombinant swinepox virus
AU8700291A (en) Hcv-specific peptides, agents therefor and the use thereof
BR9713388B1 (pt) processos de produÇço de vÍrus e de adenovÍrus recombinantes defectivos, e baculovÍrus recombinante.
AU9338598A (en) Recombinant vector containing infectious, viral genome sequences greater than 100 kb, method for producing same and use for the mutagenesis of the viral sequences
EP1006196A3 (de) Retrovirale, mit LCMV-Glykoprotein pseudotypisierte Hybrid-Vektoren
KR960001819B1 (en) Viral vector coding for a glycoprotein of the virus responsible
PL324289A1 (en) Encapsulated cells producing virus particles
EP0371119A4 (en) Retroviral vector
WO1994013812A3 (en) Novel entomopoxvirus genes, proteins and methods of use thereof
AU582288B2 (en) Vector and method for achieving high level expression in eukaryotic cells
DK498387A (da) Virus-dna-sekvens
CA2263790A1 (en) Method for immortalizing cells
CA2332623A1 (en) Recombinant herpes viruses for preparing recombinant adeno-associated viruses
NO175872C (no) Plasmidvektor, fremgangsmåte for fremstilling av peptider og myelomcelle
TH22679A (th) การเอ็กซ์เพรสโพลีเพพไทด์ของไวรัสก่อโรคทางระบบหายใจที่แพร่พันธุ์ได้ในสุกรในเซลล์เดียวกัน