ES2164910T3 - Virus auxiliares para la preparacion de vectores virales recombinantes. - Google Patents
Virus auxiliares para la preparacion de vectores virales recombinantes.Info
- Publication number
- ES2164910T3 ES2164910T3 ES96927107T ES96927107T ES2164910T3 ES 2164910 T3 ES2164910 T3 ES 2164910T3 ES 96927107 T ES96927107 T ES 96927107T ES 96927107 T ES96927107 T ES 96927107T ES 2164910 T3 ES2164910 T3 ES 2164910T3
- Authority
- ES
- Spain
- Prior art keywords
- recombinant viral
- preparation
- viral vectors
- auxiliary viruses
- recombinase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10351—Methods of production or purification of viral material
- C12N2710/10352—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/30—Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A NUEVOS VECTORES AUXILIARES (HELPER SEGUN LA DENOMINACION INGLESA) QUE PERMITEN COMPLEMENTAR VECTORES VIRICOS RECOMBINANTES DEFECTIVOS QUE PRESENTAN LA CARACTERISTICA DE ESTAR PROVISTOS DE SECUENCIAS DE RECOMBINACION RECONOCIDAS POR UNA RECOMBINASA. TIENE ASIMISMO POR OBJETO UNA CELULA DE COMPLEMENTACION QUE EXPRESA LA RECOMBINASA Y UN METODO DE PREPARACION DE LOS VECTORES VIRICOS RECOMBINANTES EN FORMA DE PARTICULAS VIRICAS INFECCIOSAS QUE PERMITEN LA TRANSFERENCIA Y EXPRESION DE GENES DE INTERES EN UNA CELULA O UN ORGANISMO HOSPEDANTE. LA INVENCION PRESENTA INTERES EN PARTICULAR PARA EL TRATAMIENTO GENETICO, EN PARTICULAR EN EL HOMBRE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9509289A FR2737501B1 (fr) | 1995-07-31 | 1995-07-31 | Nouveaux virus auxiliaires pour la preparation de vecteurs viraux recombinants |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2164910T3 true ES2164910T3 (es) | 2002-03-01 |
Family
ID=9481555
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96927107T Expired - Lifetime ES2164910T3 (es) | 1995-07-31 | 1996-07-30 | Virus auxiliares para la preparacion de vectores virales recombinantes. |
Country Status (12)
Country | Link |
---|---|
US (3) | US6066478A (es) |
EP (2) | EP1132478A3 (es) |
JP (1) | JP3416143B2 (es) |
AT (1) | ATE207959T1 (es) |
AU (1) | AU715487B2 (es) |
CA (1) | CA2225551A1 (es) |
DE (1) | DE69616559T2 (es) |
DK (1) | DK0842279T3 (es) |
ES (1) | ES2164910T3 (es) |
FR (1) | FR2737501B1 (es) |
PT (1) | PT842279E (es) |
WO (1) | WO1997005255A2 (es) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020146392A1 (en) * | 1993-06-24 | 2002-10-10 | Frank L. Graham | Helper dependent adenovirus vectors based on site-specific recombinases |
US20020136708A1 (en) | 1993-06-24 | 2002-09-26 | Graham Frank L. | System for production of helper dependent adenovirus vectors based on use of endonucleases |
US7045347B2 (en) | 1993-06-24 | 2006-05-16 | Advec, Inc. | Helper dependent adenovirus vectors based on integrase family site-specific recombinases |
JP4216350B2 (ja) * | 1994-09-19 | 2009-01-28 | 大日本住友製薬株式会社 | 動物細胞感染用の組換えdnaウイルスベクター |
AU2004201152B2 (en) * | 1995-06-07 | 2007-03-08 | Advec, Inc. | Helper Dependent Adenovirus Vectors Based on Site-specific Recombinases |
US6783980B2 (en) | 1995-06-15 | 2004-08-31 | Crucell Holland B.V. | Packaging systems for human recombinant adenovirus to be used in gene therapy |
US6265212B1 (en) | 1995-06-15 | 2001-07-24 | Introgene B.V. | Packaging systems for human recombinant adenovirus to be used in gene therapy |
JP4051416B2 (ja) * | 1995-06-15 | 2008-02-27 | クルーセル ホランド ベスローテン フェンノートシャップ | 遺伝子治療に使用されるヒト組換えアデノウイルス用のパッケージングシステム |
WO1999041400A1 (en) * | 1998-02-17 | 1999-08-19 | Genzyme Corporation | Methods for pseudoadenoviral vector production |
AUPP249298A0 (en) * | 1998-03-20 | 1998-04-23 | Ag-Gene Australia Limited | Synthetic genes and genetic constructs comprising same I |
BRPI9908967B1 (pt) * | 1998-03-20 | 2017-05-30 | Benitec Australia Ltd | processos para reprimir, retardar ou de outro modo reduzir a expressão de um gene alvo em uma célula de planta |
US20040214330A1 (en) * | 1999-04-07 | 2004-10-28 | Waterhouse Peter Michael | Methods and means for obtaining modified phenotypes |
US8598332B1 (en) * | 1998-04-08 | 2013-12-03 | Bayer Cropscience N.V. | Methods and means for obtaining modified phenotypes |
US6670188B1 (en) | 1998-04-24 | 2003-12-30 | Crucell Holland B.V. | Packaging systems for human recombinant adenovirus to be used in gene therapy |
DE69920033T3 (de) * | 1998-11-13 | 2009-10-08 | Stryker Corp., Kalamazoo | Verminderung von Prostatakrebssymptomen |
US6423885B1 (en) | 1999-08-13 | 2002-07-23 | Commonwealth Scientific And Industrial Research Organization (Csiro) | Methods for obtaining modified phenotypes in plant cells |
JP2004532039A (ja) * | 2001-03-26 | 2004-10-21 | ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ | ヘルパー依存性アデノウイルスベクター系およびその系の使用方法 |
DE10159167A1 (de) * | 2001-12-03 | 2003-10-02 | Guenter Cichon | Expressionssystem |
NZ536899A (en) * | 2002-05-02 | 2008-04-30 | Univ Rochester | Vectors having both isoforms of beta-hexosaminidase |
US20050101961A1 (en) * | 2003-11-12 | 2005-05-12 | Huebner Randall J. | Bone screws |
WO2004011624A2 (en) * | 2002-07-31 | 2004-02-05 | Nucleonics, Inc. | Double stranded rna structures and constructs, and methods for generating and using the same |
US20040203133A1 (en) * | 2003-01-07 | 2004-10-14 | Anja Ehrhardt | Helper dependent adenoviral vector system and methods for using the same |
US7686839B2 (en) * | 2005-01-26 | 2010-03-30 | Lumitex, Inc. | Phototherapy treatment devices for applying area lighting to a wound |
ES2337973B8 (es) * | 2008-05-16 | 2011-07-21 | Proyecto De Biomedicina Cima, S.L. | Adenovirus auxiliares auto-inactivantes para la produccion de adenovirus recombinantes de alta capacidad. |
US20130183740A1 (en) * | 2010-06-02 | 2013-07-18 | Avir Green Hills Biotechnology Research Development Trade Ag | Novel method for generation of rna virus |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE83008T1 (de) * | 1987-07-21 | 1992-12-15 | Du Pont Merck Pharma | Verfahren fuer die herstellung von in tierischen zellen stabilen und lebensfaehigen rekombinanten viralen vektoren. |
US5173414A (en) * | 1990-10-30 | 1992-12-22 | Applied Immune Sciences, Inc. | Production of recombinant adeno-associated virus vectors |
US5919676A (en) * | 1993-06-24 | 1999-07-06 | Advec, Inc. | Adenoviral vector system comprising Cre-loxP recombination |
FR2707664B1 (fr) * | 1993-07-13 | 1995-09-29 | Centre Nat Rech Scient | Vecteurs viraux et utilisation en thérapie génique. |
JP3770333B2 (ja) * | 1995-03-15 | 2006-04-26 | 大日本住友製薬株式会社 | 組換えdnaウイルスおよびその製造方法 |
-
1995
- 1995-07-31 FR FR9509289A patent/FR2737501B1/fr not_active Expired - Fee Related
-
1996
- 1996-07-30 ES ES96927107T patent/ES2164910T3/es not_active Expired - Lifetime
- 1996-07-30 PT PT96927107T patent/PT842279E/pt unknown
- 1996-07-30 CA CA002225551A patent/CA2225551A1/fr not_active Abandoned
- 1996-07-30 EP EP01108475A patent/EP1132478A3/fr not_active Withdrawn
- 1996-07-30 DK DK96927107T patent/DK0842279T3/da active
- 1996-07-30 DE DE69616559T patent/DE69616559T2/de not_active Expired - Fee Related
- 1996-07-30 AU AU67044/96A patent/AU715487B2/en not_active Ceased
- 1996-07-30 US US09/011,257 patent/US6066478A/en not_active Expired - Fee Related
- 1996-07-30 WO PCT/FR1996/001200 patent/WO1997005255A2/fr active IP Right Grant
- 1996-07-30 EP EP96927107A patent/EP0842279B1/fr not_active Expired - Lifetime
- 1996-07-30 JP JP50729197A patent/JP3416143B2/ja not_active Expired - Fee Related
- 1996-07-30 AT AT96927107T patent/ATE207959T1/de not_active IP Right Cessation
-
2000
- 2000-05-02 US US09/563,239 patent/US6350575B1/en not_active Expired - Fee Related
-
2001
- 2001-08-03 US US09/920,932 patent/US20020072120A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO1997005255A3 (fr) | 1997-03-06 |
WO1997005255A2 (fr) | 1997-02-13 |
US6350575B1 (en) | 2002-02-26 |
US6066478A (en) | 2000-05-23 |
ATE207959T1 (de) | 2001-11-15 |
JPH11510049A (ja) | 1999-09-07 |
AU715487B2 (en) | 2000-02-03 |
EP1132478A2 (fr) | 2001-09-12 |
EP1132478A3 (fr) | 2002-09-04 |
EP0842279B1 (fr) | 2001-10-31 |
DE69616559D1 (de) | 2001-12-06 |
DK0842279T3 (da) | 2002-02-25 |
CA2225551A1 (fr) | 1997-02-13 |
FR2737501A1 (fr) | 1997-02-07 |
EP0842279A2 (fr) | 1998-05-20 |
JP3416143B2 (ja) | 2003-06-16 |
DE69616559T2 (de) | 2002-06-27 |
US20020072120A1 (en) | 2002-06-13 |
FR2737501B1 (fr) | 1997-10-24 |
PT842279E (pt) | 2002-04-29 |
AU6704496A (en) | 1997-02-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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