PT832241E - Mutantes de toxina a estreptococica e metodos de utilizacao - Google Patents

Mutantes de toxina a estreptococica e metodos de utilizacao

Info

Publication number
PT832241E
PT832241E PT96921589T PT96921589T PT832241E PT 832241 E PT832241 E PT 832241E PT 96921589 T PT96921589 T PT 96921589T PT 96921589 T PT96921589 T PT 96921589T PT 832241 E PT832241 E PT 832241E
Authority
PT
Portugal
Prior art keywords
spe
methods
toxin
vaccine
toxins
Prior art date
Application number
PT96921589T
Other languages
English (en)
Inventor
Patrick M Schlievert
Roggiani Manuela
Stoehr Jennifer
Ohlendorf Douglas
Original Assignee
Univ Minnesota
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Minnesota filed Critical Univ Minnesota
Publication of PT832241E publication Critical patent/PT832241E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PT96921589T 1995-06-07 1996-06-07 Mutantes de toxina a estreptococica e metodos de utilizacao PT832241E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US48026195A 1995-06-07 1995-06-07

Publications (1)

Publication Number Publication Date
PT832241E true PT832241E (pt) 2005-08-31

Family

ID=23907283

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96921589T PT832241E (pt) 1995-06-07 1996-06-07 Mutantes de toxina a estreptococica e metodos de utilizacao

Country Status (12)

Country Link
US (3) US6632441B2 (pt)
EP (2) EP0832241B1 (pt)
JP (1) JPH11514844A (pt)
KR (1) KR100456594B1 (pt)
AT (1) ATE291625T1 (pt)
AU (1) AU723116B2 (pt)
CA (1) CA2221480A1 (pt)
DE (1) DE69634510T2 (pt)
DK (1) DK0832241T3 (pt)
ES (1) ES2239332T3 (pt)
PT (1) PT832241E (pt)
WO (1) WO1996040930A1 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW517061B (en) * 1996-03-29 2003-01-11 Pharmacia & Amp Upjohn Ab Modified/chimeric superantigens and their use
US6774218B2 (en) 1996-12-06 2004-08-10 Regents Of The University Of Minnesota Mutants of streptococcal toxin C and methods of use
WO1998024911A2 (en) * 1996-12-06 1998-06-11 Regents Of The University Of Minnesota Mutants of streptococcal toxin a and methods of use
WO1998024910A2 (en) 1996-12-06 1998-06-11 Regents Of The University Of Minnesota Mutants of streptococcal toxin c and methods of use
US6075119A (en) 1997-04-07 2000-06-13 The Rockefeller University Peptides useful for reducing symptoms of toxic shock syndrome
US7087235B2 (en) * 1997-06-25 2006-08-08 The United States Of America As Represented By The Secretary Of The Army Fusion protein of streptococcal pyrogenic exotoxins
US6872394B1 (en) 1997-12-02 2005-03-29 Idaho Research Foundation, Inc. Non-toxic immune stimulating enterotoxin compositions
AU6059799A (en) * 1998-10-07 2000-04-26 Rockefeller University, The Peptides useful for reducing symptoms of toxic shock syndrome and septic shock
US20040236082A1 (en) * 2001-04-13 2004-11-25 Marshall Matthew J. Modified staphylococcal enterotoxins and expression systems therefore
SE0102327D0 (sv) * 2001-06-28 2001-06-28 Active Biotech Ab A novel engineered superantigen for human therapy
US20070178113A1 (en) * 2005-11-22 2007-08-02 Backstrom B T Superantigen conjugate
CA2683748C (en) 2007-04-13 2016-02-16 The Board Of Regents Of The University Of Oklahoma Mutants of cholesterol-dependent cytolysins and uses thereof
WO2015200833A2 (en) 2014-06-27 2015-12-30 Abbott Laboratories COMPOSITIONS AND METHODS FOR DETECTING HUMAN PEGIVIRUS 2 (HPgV-2)
CA2968398A1 (en) 2014-11-21 2016-05-26 The Board Of Regents Of The University Of Oklahoma Pneumolysin mutants and methods of use thereof
EP3411409A2 (en) 2016-01-10 2018-12-12 Neotx Therapeutics Ltd. Immunopotentiator enhanced superantigen mediated cancer immunotherapy
CN114025791A (zh) 2019-05-15 2022-02-08 尼奥克斯医疗有限公司 癌症治疗
CN115484978A (zh) 2020-03-05 2022-12-16 尼奥克斯医疗有限公司 使用免疫细胞治疗癌症的方法和组合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4784948A (en) * 1983-08-10 1988-11-15 The Rockefeller University Production of streptococcal m protein immunogens and molecular probes
US5336598A (en) 1989-11-15 1994-08-09 National Jewish Center For Immunology And Respiratory Medicine Method for diagnosing a superantigen caused pathologial condition via assay of T-cells
US5298396A (en) 1989-11-15 1994-03-29 National Jewish Center For Immunology And Respiratory Medicine Method for identifying T cells disease involved in autoimmune disease
WO1993014634A1 (en) 1992-01-28 1993-08-05 National Jewish Center For Immunology And Respiratory Medicine Protective effects of mutated superantigens

Also Published As

Publication number Publication date
EP1538208A2 (en) 2005-06-08
WO1996040930A1 (en) 1996-12-19
JPH11514844A (ja) 1999-12-21
ES2239332T3 (es) 2005-09-16
US20020054887A1 (en) 2002-05-09
KR19990022750A (ko) 1999-03-25
EP1538208A3 (en) 2007-05-23
DE69634510D1 (de) 2005-04-28
AU6278296A (en) 1996-12-30
DE69634510T2 (de) 2006-01-26
US20060039925A1 (en) 2006-02-23
EP0832241A1 (en) 1998-04-01
KR100456594B1 (ko) 2005-06-17
US6632441B2 (en) 2003-10-14
CA2221480A1 (en) 1996-12-19
US6870042B1 (en) 2005-03-22
EP0832241B1 (en) 2005-03-23
ATE291625T1 (de) 2005-04-15
AU723116B2 (en) 2000-08-17
DK0832241T3 (da) 2005-08-01

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