PT826681E - Derivados de acido epoxi-succinico - Google Patents

Derivados de acido epoxi-succinico

Info

Publication number
PT826681E
PT826681E PT96907747T PT96907747T PT826681E PT 826681 E PT826681 E PT 826681E PT 96907747 T PT96907747 T PT 96907747T PT 96907747 T PT96907747 T PT 96907747T PT 826681 E PT826681 E PT 826681E
Authority
PT
Portugal
Prior art keywords
aralkyl
alkyl
acid derivatives
epoxy
succinic acid
Prior art date
Application number
PT96907747T
Other languages
English (en)
Inventor
Mitsuo Masaki
Yutaka Nomura
Toshihiro Takahashi
Kaoru Hara
Yasushi Yoshino
Original Assignee
Nippon Chemiphar Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Chemiphar Co filed Critical Nippon Chemiphar Co
Publication of PT826681E publication Critical patent/PT826681E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/38—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D303/46—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by amide or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
PT96907747T 1995-03-31 1996-04-01 Derivados de acido epoxi-succinico PT826681E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10050495 1995-03-31

Publications (1)

Publication Number Publication Date
PT826681E true PT826681E (pt) 2003-02-28

Family

ID=14275780

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96907747T PT826681E (pt) 1995-03-31 1996-04-01 Derivados de acido epoxi-succinico

Country Status (13)

Country Link
US (1) US5843992A (pt)
EP (1) EP0826681B1 (pt)
KR (1) KR100381275B1 (pt)
CN (1) CN1087295C (pt)
AT (1) ATE225781T1 (pt)
AU (1) AU716620B2 (pt)
CA (1) CA2217051C (pt)
DE (1) DE69624235T2 (pt)
DK (1) DK0826681T3 (pt)
EA (1) EA000438B1 (pt)
ES (1) ES2184855T3 (pt)
PT (1) PT826681E (pt)
WO (1) WO1996030354A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3464397A (en) * 1996-07-02 1998-01-21 Sang Sup Jew Oxirane carboxylic acid derivative and its manufacturing method
CN1255121A (zh) * 1997-02-26 2000-05-31 伊莱利利公司 制备药用化合物的选择性环氧化的方法
ATE241607T1 (de) 1997-09-04 2003-06-15 Nippon Chemiphar Co Epoxybernsteinsäureamid-derivate
WO2008045017A2 (en) * 2005-06-22 2008-04-17 Diamond Scott L Sars and ebola inhibitors and use thereof, and methods for their discovery
WO2007038772A1 (en) * 2005-09-28 2007-04-05 American Life Science Pharmaceuticals Novel drugs for dementia
EP2019688A2 (en) * 2006-05-22 2009-02-04 Velcura Therapeutics, Inc. Use of cathepsin k antagonists in bone production
US20100216875A1 (en) * 2006-12-20 2010-08-26 Gregory Hook Methods of treating alzheimer's disease
US20110092484A1 (en) 2007-06-08 2011-04-21 Nippon Chemiphar Co., Ltd. Therapeutic or prophylactic agent for cerebral aneurysm
EP2216047A4 (en) 2007-10-24 2011-12-28 Nat Univ Corp Tokyo Med & Dent REGULATOR FOR SIGNALING THE TOLL LIKE RECEPTOR WITH A CATHEPSIN INHIBITOR AS AN ACTIVE SUBSTANCE
RU2756956C2 (ru) * 2020-03-26 2021-10-07 Публичное акционерное общество «СИБУР Холдинг» Способ получения кристаллической формы цис-2,3-эпоксисукцината кальция

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5547668A (en) * 1978-09-30 1980-04-04 Taisho Pharmaceut Co Ltd Epoxysuccinamic acid
US4418705A (en) * 1979-05-22 1983-12-06 G. D. Societa Per Azioni Method and relative manufacturing machine for simultaneously producing two continuous cigarette rods
EP0269311A3 (en) * 1986-11-17 1990-06-06 Merck & Co. Inc. Methods of treating bone diseases by administration of a cysteine proteinase inhibitor
WO1996030378A1 (fr) * 1995-03-31 1996-10-03 Nippon Chemiphar Co., Ltd. Derives d'acide bisphosphonique
US5733911A (en) * 1996-01-26 1998-03-31 Hitachi Chemical Co., Ltd. Method for inducing death of neoplastic cells using piperazne derivatives

Also Published As

Publication number Publication date
EP0826681A4 (pt) 1998-03-18
WO1996030354A1 (fr) 1996-10-03
AU5123296A (en) 1996-10-16
CA2217051A1 (en) 1996-10-03
DE69624235T2 (de) 2003-06-26
KR100381275B1 (ko) 2003-08-19
ES2184855T3 (es) 2003-04-16
EP0826681A1 (en) 1998-03-04
DE69624235D1 (de) 2002-11-14
EP0826681B1 (en) 2002-10-09
CN1087295C (zh) 2002-07-10
EA000438B1 (ru) 1999-08-26
EA199800181A1 (ru) 1998-08-27
KR19980703485A (ko) 1998-11-05
US5843992A (en) 1998-12-01
ATE225781T1 (de) 2002-10-15
CA2217051C (en) 2006-05-30
AU716620B2 (en) 2000-03-02
DK0826681T3 (da) 2003-02-17
CN1185151A (zh) 1998-06-17

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