ATE225781T1 - Derivate der epoxybernsteinsäure - Google Patents

Derivate der epoxybernsteinsäure

Info

Publication number
ATE225781T1
ATE225781T1 AT96907747T AT96907747T ATE225781T1 AT E225781 T1 ATE225781 T1 AT E225781T1 AT 96907747 T AT96907747 T AT 96907747T AT 96907747 T AT96907747 T AT 96907747T AT E225781 T1 ATE225781 T1 AT E225781T1
Authority
AT
Austria
Prior art keywords
aralkyl
alkyl
aryl
derivatives
treatment
Prior art date
Application number
AT96907747T
Other languages
English (en)
Inventor
Yutaka Nomura
Toshihiro Takahashi
Kaoru Hara
Yasushi Yoshino
Mitsuo Masaki
Original Assignee
Nippon Chemiphar Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Chemiphar Co filed Critical Nippon Chemiphar Co
Application granted granted Critical
Publication of ATE225781T1 publication Critical patent/ATE225781T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/38—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D303/46—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by amide or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Resins (AREA)
AT96907747T 1995-03-31 1996-04-01 Derivate der epoxybernsteinsäure ATE225781T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10050495 1995-03-31
PCT/JP1996/000889 WO1996030354A1 (fr) 1995-03-31 1996-04-01 Derives d'acide epoxysuccinique

Publications (1)

Publication Number Publication Date
ATE225781T1 true ATE225781T1 (de) 2002-10-15

Family

ID=14275780

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96907747T ATE225781T1 (de) 1995-03-31 1996-04-01 Derivate der epoxybernsteinsäure

Country Status (13)

Country Link
US (1) US5843992A (de)
EP (1) EP0826681B1 (de)
KR (1) KR100381275B1 (de)
CN (1) CN1087295C (de)
AT (1) ATE225781T1 (de)
AU (1) AU716620B2 (de)
CA (1) CA2217051C (de)
DE (1) DE69624235T2 (de)
DK (1) DK0826681T3 (de)
EA (1) EA000438B1 (de)
ES (1) ES2184855T3 (de)
PT (1) PT826681E (de)
WO (1) WO1996030354A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3464397A (en) * 1996-07-02 1998-01-21 Sang Sup Jew Oxirane carboxylic acid derivative and its manufacturing method
NZ336918A (en) * 1997-02-26 2001-11-30 Lilly Co Eli Selective epoxidation process for preparing pharmaceutical compounds comprising Cryptophycin 52
PT1022276E (pt) 1997-09-04 2003-10-31 Nippon Chemiphar Co Derivados de epoxissuccinamida
WO2008045017A2 (en) * 2005-06-22 2008-04-17 Diamond Scott L Sars and ebola inhibitors and use thereof, and methods for their discovery
WO2007038772A1 (en) * 2005-09-28 2007-04-05 American Life Science Pharmaceuticals Novel drugs for dementia
AU2007253796A1 (en) * 2006-05-22 2007-11-29 Velcura Therapeutics, Inc. Use of Cathepsin K antagonists in bone production
US20100216875A1 (en) * 2006-12-20 2010-08-26 Gregory Hook Methods of treating alzheimer's disease
KR20100023948A (ko) 2007-06-08 2010-03-04 닛뽕 케미파 가부시키가이샤 뇌동맥류의 치료 또는 예방약
WO2009054454A1 (ja) 2007-10-24 2009-04-30 National University Corporation Tokyo Medical And Dental University カテプシン阻害剤を有効成分として含有するＴｏｌｌ様受容体のシグナル伝達の調整剤
RU2756956C2 (ru) * 2020-03-26 2021-10-07 Публичное акционерное общество «СИБУР Холдинг» Способ получения кристаллической формы цис-2,3-эпоксисукцината кальция

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5547668A (en) * 1978-09-30 1980-04-04 Taisho Pharmaceut Co Ltd Epoxysuccinamic acid
US4418705A (en) * 1979-05-22 1983-12-06 G. D. Societa Per Azioni Method and relative manufacturing machine for simultaneously producing two continuous cigarette rods
EP0269311A3 (de) * 1986-11-17 1990-06-06 Merck & Co. Inc. Methoden zur Behandlung von Knochenleiden mittels Verabreichung von Cystein-Proteinaseinhibitoren
AU5123196A (en) * 1995-03-31 1996-10-16 Nippon Chemiphar Co. Ltd. Bisphosphonic acid derivatives
US5733911A (en) * 1996-01-26 1998-03-31 Hitachi Chemical Co., Ltd. Method for inducing death of neoplastic cells using piperazne derivatives

Also Published As

Publication number Publication date
CN1185151A (zh) 1998-06-17
DK0826681T3 (da) 2003-02-17
DE69624235D1 (de) 2002-11-14
EA000438B1 (ru) 1999-08-26
ES2184855T3 (es) 2003-04-16
EP0826681A1 (de) 1998-03-04
CA2217051A1 (en) 1996-10-03
DE69624235T2 (de) 2003-06-26
US5843992A (en) 1998-12-01
PT826681E (pt) 2003-02-28
CN1087295C (zh) 2002-07-10
CA2217051C (en) 2006-05-30
WO1996030354A1 (fr) 1996-10-03
EP0826681B1 (de) 2002-10-09
EP0826681A4 (de) 1998-03-18
KR100381275B1 (ko) 2003-08-19
EA199800181A1 (ru) 1998-08-27
KR19980703485A (ko) 1998-11-05
AU716620B2 (en) 2000-03-02
AU5123296A (en) 1996-10-16

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