PT80663B - Process for preparing epoxysteroids - Google Patents
Process for preparing epoxysteroidsInfo
- Publication number
- PT80663B PT80663B PT80663A PT8066385A PT80663B PT 80663 B PT80663 B PT 80663B PT 80663 A PT80663 A PT 80663A PT 8066385 A PT8066385 A PT 8066385A PT 80663 B PT80663 B PT 80663B
- Authority
- PT
- Portugal
- Prior art keywords
- epoxysteroids
- preparing
- preparing epoxysteroids
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
- C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
- C07J53/002—Carbocyclic rings fused
- C07J53/004—3 membered carbocyclic rings
- C07J53/008—3 membered carbocyclic rings in position 15/16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
- C07J71/0015—Oxiranes at position 9(11)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH300984 | 1984-06-21 | ||
| CH464684 | 1984-09-28 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT80663A PT80663A (en) | 1985-07-01 |
| PT80663B true PT80663B (en) | 1987-05-08 |
Family
ID=25691934
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT80663A PT80663B (en) | 1984-06-21 | 1985-06-19 | Process for preparing epoxysteroids |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4670551A (OSRAM) |
| EP (1) | EP0165902B1 (OSRAM) |
| AR (2) | AR242036A1 (OSRAM) |
| AU (1) | AU582754B2 (OSRAM) |
| CA (1) | CA1239388A (OSRAM) |
| DE (1) | DE3569540D1 (OSRAM) |
| DK (1) | DK173854B1 (OSRAM) |
| ES (2) | ES8704967A1 (OSRAM) |
| FI (1) | FI83225C (OSRAM) |
| GR (1) | GR851499B (OSRAM) |
| HU (1) | HU192232B (OSRAM) |
| IE (1) | IE58050B1 (OSRAM) |
| IL (1) | IL75569A (OSRAM) |
| NO (1) | NO165496C (OSRAM) |
| NZ (1) | NZ212492A (OSRAM) |
| PT (1) | PT80663B (OSRAM) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0973791B1 (en) * | 1995-12-11 | 2007-06-20 | G.D. Searle LLC. | Process for the preparation of an epoxy compound |
| DE69738225T2 (de) | 1996-12-11 | 2008-07-17 | G.D. Searle Llc, Chicago | Epoxidierungsverfahren |
| US6887991B1 (en) | 1996-12-11 | 2005-05-03 | G. D. Searle & Company | Processes for preparation of 9, 11-epoxy steroids and intermediates useful therein |
| EP1148061B1 (en) * | 1996-12-11 | 2007-10-17 | G.D. Searle LLC. | Epoxidation process |
| WO1999061055A1 (en) | 1998-05-22 | 1999-12-02 | The Board Of Trustees Of The Leland Stanford Junior University | Bifunctional molecules and therapies based thereon |
| PL371128A1 (en) | 2001-12-12 | 2005-06-13 | Pharmacia Corporation | Method of treating ophthalmic disorders with epoxy-steroidal aldosterone receptor antagonists |
| US7235655B2 (en) | 2002-03-22 | 2007-06-26 | Pharmacia & Upjohn Company | Processes to prepare eplerenone |
| CN101287411B (zh) | 2005-04-28 | 2013-03-06 | 普罗秋斯生物医学公司 | 药物信息系统及其用途 |
| WO2007025780A2 (en) * | 2005-09-02 | 2007-03-08 | Recordati Ireland Limited | Aldosterone receptor antagonists |
| EP1945240B1 (en) | 2005-09-16 | 2016-12-28 | Raptor Pharmaceutical Inc | Compositions comprising receptor-associated protein (rap) variants specific for cr-containing proteins and uses thereof |
| NZ594310A (en) | 2009-02-20 | 2014-02-28 | To Bbb Holding B V | Glutathione-based drug delivery system |
| TWI556839B (zh) | 2009-05-06 | 2016-11-11 | 研究室護膚股份有限公司 | 包含活性劑－磷酸鈣粒子複合物之皮膚遞送組成物及其使用方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3013012A (en) * | 1960-12-22 | 1961-12-12 | Searle & Co | Alkanoylthio-17alpha-carboxyethyl-17beta-hydroxyandrosten-3-one lactones |
| US3095412A (en) * | 1961-12-19 | 1963-06-25 | Searle & Co | 9alpha, 11alpha-epoxy and 11beta-chloro-9alpha-hydroxy 17alpha-(2-carboxyethyl)-17beta-hydroxyandrost-4-en-3-one gamma-lactones and delta1 and delta6 analogs |
| GB1041534A (en) * | 1963-04-24 | 1966-09-07 | Merck & Co Inc | 20-spiroxane compounds |
| DE2652761C2 (de) * | 1976-11-16 | 1985-11-21 | Schering AG, 1000 Berlin und 4709 Bergkamen | 15,16-Methylen-Spirolactone, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel |
| US4559332A (en) * | 1983-04-13 | 1985-12-17 | Ciba Geigy Corporation | 20-Spiroxanes and analogues having an open ring E, processes for their manufacture, and pharmaceutical preparations thereof |
| DE3481707D1 (de) * | 1983-08-17 | 1990-04-26 | Schering Ag | 7-alpha-substituierte 3-oxo-17alpha-pregn-4-en-21.17-carbolactone, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate. |
-
1985
- 1985-06-13 US US06/744,444 patent/US4670551A/en not_active Expired - Fee Related
- 1985-06-17 EP EP85810277A patent/EP0165902B1/de not_active Expired
- 1985-06-17 DE DE8585810277T patent/DE3569540D1/de not_active Expired
- 1985-06-19 IL IL75569A patent/IL75569A/xx not_active IP Right Cessation
- 1985-06-19 FI FI852430A patent/FI83225C/fi not_active IP Right Cessation
- 1985-06-19 CA CA000484418A patent/CA1239388A/en not_active Expired
- 1985-06-19 GR GR851499A patent/GR851499B/el unknown
- 1985-06-19 PT PT80663A patent/PT80663B/pt not_active IP Right Cessation
- 1985-06-20 ES ES544387A patent/ES8704967A1/es not_active Expired
- 1985-06-20 NZ NZ212492A patent/NZ212492A/xx unknown
- 1985-06-20 DK DK198502800A patent/DK173854B1/da not_active IP Right Cessation
- 1985-06-20 NO NO852501A patent/NO165496C/no unknown
- 1985-06-20 HU HU852433A patent/HU192232B/hu not_active IP Right Cessation
- 1985-06-20 IE IE153585A patent/IE58050B1/en not_active IP Right Cessation
- 1985-06-21 AR AR85300773A patent/AR242036A1/es active
- 1985-06-21 AU AU43971/85A patent/AU582754B2/en not_active Ceased
-
1986
- 1986-10-01 ES ES557112A patent/ES8707737A1/es not_active Expired
-
1989
- 1989-07-31 AR AR89314546A patent/AR245731A1/es active
Also Published As
| Publication number | Publication date |
|---|---|
| FI852430A0 (fi) | 1985-06-19 |
| AR245731A1 (es) | 1994-02-28 |
| PT80663A (en) | 1985-07-01 |
| DK173854B1 (da) | 2001-12-27 |
| GR851499B (OSRAM) | 1985-11-25 |
| IE851535L (en) | 1985-12-21 |
| IL75569A (en) | 1989-03-31 |
| DK280085A (da) | 1985-12-22 |
| ES544387A0 (es) | 1987-04-16 |
| CA1239388A (en) | 1988-07-19 |
| NZ212492A (en) | 1989-02-24 |
| US4670551A (en) | 1987-06-02 |
| NO165496C (no) | 1991-02-20 |
| HU192232B (en) | 1987-05-28 |
| ES557112A0 (es) | 1987-08-16 |
| NO165496B (no) | 1990-11-12 |
| IL75569A0 (en) | 1985-10-31 |
| EP0165902A3 (en) | 1986-10-22 |
| FI83225C (fi) | 1991-06-10 |
| FI83225B (fi) | 1991-02-28 |
| DE3569540D1 (en) | 1989-05-24 |
| ES8704967A1 (es) | 1987-04-16 |
| FI852430L (fi) | 1985-12-22 |
| IE58050B1 (en) | 1993-06-16 |
| AR242036A1 (es) | 1993-02-26 |
| ES8707737A1 (es) | 1987-08-16 |
| AU582754B2 (en) | 1989-04-13 |
| NO852501L (no) | 1985-12-23 |
| EP0165902B1 (de) | 1989-04-19 |
| DK280085D0 (da) | 1985-06-20 |
| HUT38367A (en) | 1986-05-28 |
| AU4397185A (en) | 1986-01-02 |
| EP0165902A2 (de) | 1985-12-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC3A | Transfer or assignment |
Free format text: 970618 NOVARTIS AG CH |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20031130 |