PT796262E - Derivados de acido 7-alquilidenocefalosporanico e metodos para a sua utilizacao - Google Patents

Derivados de acido 7-alquilidenocefalosporanico e metodos para a sua utilizacao

Info

Publication number
PT796262E
PT796262E PT95941506T PT95941506T PT796262E PT 796262 E PT796262 E PT 796262E PT 95941506 T PT95941506 T PT 95941506T PT 95941506 T PT95941506 T PT 95941506T PT 796262 E PT796262 E PT 796262E
Authority
PT
Portugal
Prior art keywords
spanic
alkylidenocepal
methods
acid derivatives
derivatives
Prior art date
Application number
PT95941506T
Other languages
English (en)
Inventor
John D Buynak
Brian Bachmann
Original Assignee
Res Corp Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Corp Technologies Inc filed Critical Res Corp Technologies Inc
Publication of PT796262E publication Critical patent/PT796262E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT95941506T 1994-12-09 1995-12-11 Derivados de acido 7-alquilidenocefalosporanico e metodos para a sua utilizacao PT796262E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/354,850 US5629306A (en) 1994-12-09 1994-12-09 7-alkylidene cephalosporanic acid derivatives and methods of using the same

Publications (1)

Publication Number Publication Date
PT796262E true PT796262E (pt) 2004-08-31

Family

ID=23395164

Family Applications (1)

Application Number Title Priority Date Filing Date
PT95941506T PT796262E (pt) 1994-12-09 1995-12-11 Derivados de acido 7-alquilidenocefalosporanico e metodos para a sua utilizacao

Country Status (11)

Country Link
US (3) US5629306A (pt)
EP (1) EP0796262B1 (pt)
JP (1) JP3241737B2 (pt)
AT (1) ATE263173T1 (pt)
AU (1) AU4290796A (pt)
BR (1) BR9509889A (pt)
CA (1) CA2206699C (pt)
DE (1) DE69532820T2 (pt)
ES (1) ES2218557T3 (pt)
PT (1) PT796262E (pt)
WO (1) WO1996017849A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5629306A (en) 1994-12-09 1997-05-13 Research Corporation Technologies, Inc. 7-alkylidene cephalosporanic acid derivatives and methods of using the same
US5760027A (en) * 1996-12-06 1998-06-02 Research Corporation Technologies, Inc. Use of 7-alkylidene cephalosporins to inhibit elastase activity
US6156745A (en) * 1997-12-29 2000-12-05 Research Corporation Technologies, Inc. 2β-substituted-6-alkylidene penicillanic acid derivatives as β-lactamase inhibitors
CA2318366C (en) 1997-12-29 2006-05-23 Research Corporation Technologies, Inc. Process for the preparation of .alpha.-oxolactams
JP2002542249A (ja) * 1999-04-15 2002-12-10 リサーチ コーポレイション テクノロジーズ，インコーポレイティド β−ラクタマーゼ阻害化合物
US6407091B1 (en) 1999-04-15 2002-06-18 Research Corporation Technologies, Inc. β-lactamase inhibiting compounds
EP1359153B1 (en) * 1999-04-15 2006-06-21 Research Corporation Technologies, Inc Beta-lactamase inhibiting compounds
US6916801B2 (en) * 2001-07-24 2005-07-12 Alamx, Llc 7-Alkylidene-3-substituted-3-cephem-4-carboxylates as β-lactamase inhibitors
JP2005525399A (ja) * 2002-04-04 2005-08-25 アラムクス エルエルシー セリンおよびメタロ−β−ラクタマーゼの阻害剤
AU2012233003B2 (en) * 2005-12-07 2014-12-18 Basilea Pharmaceutica Ag Useful combinations of monobactam antibiotics with beta-lactamase inhibitors
CN103724330B (zh) * 2005-12-07 2015-08-19 巴斯利尔药物股份公司 单环-内酰胺类抗生素与β-内酰胺酶抑制剂的有效的联合应用

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4150156A (en) * 1975-11-21 1979-04-17 Merck & Co., Inc. 7-(Substituted methyl)-3-(substituted thio)-cephalosporins, derivatives and pharmaceutical compositions containing them
DE3176517D1 (en) * 1980-04-24 1987-12-17 Beecham Group Plc Beta-lactam compounds, their preparation and use
US4459405A (en) * 1982-11-16 1984-07-10 Eli Lilly And Company Desacetylcephalosporin sulfones
EP0120613A1 (en) * 1983-03-02 1984-10-03 Beecham Group Plc Penem derivatives and precursors
US4547371A (en) * 1983-04-18 1985-10-15 Merck & Co., Inc. Substituted cephalosporin sulfones as anti-inflammatory and anti-degenerative agents
US4637999A (en) 1983-05-02 1987-01-20 Merck & Co., Inc. Substituted cephalosporins as anti-inflammatory and antidegenerative agents
US5132301A (en) * 1983-05-02 1992-07-21 Merck & Co., Inc. Substituted cephalosporin sulfones as anti-inflammatory and anti-degenerative agents
GB8518421D0 (en) * 1985-07-22 1985-08-29 Beecham Group Plc Compounds
GB8808701D0 (en) 1988-04-13 1988-05-18 Erba Carlo Spa Beta-lactam derivatives
GB8811388D0 (en) * 1988-05-13 1988-06-15 Erba Carlo Spa 1,1-dioxo-cephem-4-carbothiolic acid derivatives
US5179023A (en) 1989-03-24 1993-01-12 Research Corporation Technologies, Inc. Recombinant α-galactosidase a therapy for Fabry disease
US4992541A (en) 1989-08-01 1991-02-12 Merck & Co., Inc. Process for the preparation of 1,1-dioxo-7-substituted cephems
US5264429A (en) 1989-10-06 1993-11-23 Synphar Laboratories, Inc. 2-spirocyclopropyl cephalosporin sulfone derivatives
GB8928373D0 (en) * 1989-12-15 1990-02-21 Erba Carlo Spa Beta-lactam derivatives
US5126446A (en) * 1991-01-04 1992-06-30 Eli Lilly And Company Process for 3-exomethylenecepham sulfoxide esters
US5258377A (en) 1991-04-08 1993-11-02 Taiho Pharmaceutical Co., Ltd. 2-spirocyclopropyl 4-acylcephems
US5446037A (en) * 1991-12-05 1995-08-29 Synphar Laboratories, Inc. 2-[(substituted) methylene]cephalosporin sulfones as antiinflammatory, antidegenerative and antithrombin agents
US5597817A (en) 1994-12-09 1997-01-28 Southern Methodist University 7-vinylidene cephalosporins and methods of using the same
US5629306A (en) * 1994-12-09 1997-05-13 Research Corporation Technologies, Inc. 7-alkylidene cephalosporanic acid derivatives and methods of using the same

Also Published As

Publication number Publication date
EP0796262A1 (en) 1997-09-24
DE69532820D1 (de) 2004-05-06
WO1996017849A1 (en) 1996-06-13
ES2218557T3 (es) 2004-11-16
US5629306A (en) 1997-05-13
JPH10510265A (ja) 1998-10-06
CA2206699C (en) 2007-03-20
AU4290796A (en) 1996-06-26
EP0796262B1 (en) 2004-03-31
ATE263173T1 (de) 2004-04-15
US20020025954A1 (en) 2002-02-28
BR9509889A (pt) 1997-12-30
US6303592B1 (en) 2001-10-16
US6599892B2 (en) 2003-07-29
DE69532820T2 (de) 2005-01-13
EP0796262A4 (en) 1998-03-25
JP3241737B2 (ja) 2001-12-25
CA2206699A1 (en) 1996-06-13

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