ES552407A0 - Procedimiento para la fabricacion de derivados aminoalcoholes peptidicos inhibidores de la renina y de las proteasas acidas - Google Patents

Procedimiento para la fabricacion de derivados aminoalcoholes peptidicos inhibidores de la renina y de las proteasas acidas

Info

Publication number
ES552407A0
ES552407A0 ES552407A ES552407A ES552407A0 ES 552407 A0 ES552407 A0 ES 552407A0 ES 552407 A ES552407 A ES 552407A ES 552407 A ES552407 A ES 552407A ES 552407 A0 ES552407 A0 ES 552407A0
Authority
ES
Spain
Prior art keywords
aminoalcohole
renine
peptidic
procedure
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES552407A
Other languages
English (en)
Other versions
ES8900018A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Institut National de la Sante et de la Recherche Medicale INSERM
Original Assignee
Sanofi SA
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8502763A external-priority patent/FR2577931B1/fr
Priority claimed from FR8511728A external-priority patent/FR2585708B1/fr
Application filed by Sanofi SA, Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Sanofi SA
Publication of ES8900018A1 publication Critical patent/ES8900018A1/es
Publication of ES552407A0 publication Critical patent/ES552407A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
ES552407A 1985-02-26 1986-02-26 Procedimiento para la fabricacion de derivados aminoalcoholes peptidicos inhibidores de la renina y de las proteasas acidas Expired ES8900018A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8502763A FR2577931B1 (fr) 1985-02-26 1985-02-26 Derives aminodiols peptidiques inhibiteurs de la renine et des proteases acides, leur procede de preparation et leur application en therapeutique
FR8511728A FR2585708B1 (fr) 1985-07-31 1985-07-31 Derives aminoalcools peptidiques inhibiteurs de la resine et des proteases acides, leur procede de preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
ES8900018A1 ES8900018A1 (es) 1988-11-16
ES552407A0 true ES552407A0 (es) 1988-11-16

Family

ID=26224394

Family Applications (1)

Application Number Title Priority Date Filing Date
ES552407A Expired ES8900018A1 (es) 1985-02-26 1986-02-26 Procedimiento para la fabricacion de derivados aminoalcoholes peptidicos inhibidores de la renina y de las proteasas acidas

Country Status (9)

Country Link
EP (1) EP0214209A1 (es)
KR (1) KR860006487A (es)
AU (1) AU587426B2 (es)
DK (1) DK89286A (es)
ES (1) ES8900018A1 (es)
GR (1) GR860532B (es)
NZ (1) NZ215282A (es)
PT (1) PT82077B (es)
WO (1) WO1986004901A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4668663A (en) * 1984-03-27 1987-05-26 Merck & Co., Inc. Renin inhibitors containing homophe8
CA1290097C (en) * 1985-07-24 1991-10-01 Merck & Co., Inc. Peptide enzyme inhibitors
IL83663A0 (en) * 1986-10-27 1988-01-31 Robins Co Inc A H Preparation of 3-pyrrolidinols
NZ222755A (en) * 1986-12-23 1989-11-28 Warner Lambert Co Renin inhibiting acyl peptide derivatives containing two to four amino acid residues, and pharmaceutical compositions
DE3721855A1 (de) * 1987-03-12 1988-09-22 Merck Patent Gmbh Aminosaeurederivate
DE4136443A1 (de) * 1991-11-06 1993-05-13 Boehringer Ingelheim Int Expression der reifen proteinase 2a, ihre partielle reinigung und bereitstellung kompetitiv wirkender substrate
ZA991319B (en) 1998-02-20 2000-11-20 Ortho Mcneil Pharm Inc Novel phthalimido arylpiperazines useful in the treatment of benign prostatic hyperplasia.
EP1346983A3 (en) * 1998-02-20 2003-12-03 Ortho-Mcneil Pharmaceutical, Inc. Phthalimido arylpiperazines as alpha 1A receptor antagonists useful in the treatment of benign prostatic hyperplasia
TW536538B (en) 1998-02-20 2003-06-11 Ortho Mcneil Pharm Inc Phthalimido arylpiperazines useful in the treatment of benign prostatic hyperplasia
WO2014015934A1 (de) * 2012-07-24 2014-01-30 Merck Patent Gmbh Hydroxystatin-derivate zur behandlung von arthrose

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1245217A (en) * 1981-12-10 1988-11-22 Joshua S. Boger Renin inhibitory peptides having phe su13 xx deletion
US4595677A (en) * 1982-12-03 1986-06-17 Ciba-Geigy Corporation Substituted tetrapeptides
US4636491A (en) * 1984-03-27 1987-01-13 Merck & Co., Inc. Renin inhibitory peptides having improved solubility
US4668663A (en) * 1984-03-27 1987-05-26 Merck & Co., Inc. Renin inhibitors containing homophe8
US4661473A (en) * 1984-03-27 1987-04-28 Merck & Co., Inc. Renin inhibitors containing peptide isosteres
DE3418491A1 (de) * 1984-05-18 1985-11-21 Merck Patent Gmbh, 6100 Darmstadt Diaminosaeurederivate

Also Published As

Publication number Publication date
GR860532B (en) 1986-06-24
DK89286A (da) 1986-08-27
EP0214209A1 (fr) 1987-03-18
AU587426B2 (en) 1989-08-17
PT82077A (fr) 1986-03-01
DK89286D0 (da) 1986-02-26
ES8900018A1 (es) 1988-11-16
KR860006487A (ko) 1986-09-11
NZ215282A (en) 1989-08-29
AU5410086A (en) 1986-09-04
PT82077B (fr) 1987-09-25
WO1986004901A1 (fr) 1986-08-28

Similar Documents

Publication Publication Date Title
ES557643A0 (es) Procedimiento para la obtencion de derivados de acidos benzoheterociclilalcanoicos
ES532470A0 (es) Procedimiento para la preparacion de acidos beta-(benzotiazoliltio)-carboxilicos y acidos beta-(benzoimidazoliltio)-carboxilicos
MX162553A (es) Procedimiento para la preparacion de esteres de acido citrico
ES551820A0 (es) Un procedimiento para la fabricacion de derivados peptidicos inhibidores de la renina y de las proteasas acidas
IT1148618B (it) Procedimento enzimatico per la produzione di acido 3-indolpiruvico e utilizzazione farmaceutica di questo
ES541774A0 (es) Esteres de aminoacidos y de peptidos cromogenos
ES541775A0 (es) Esteres de aminoacidos y de peptidos cromogenos
ES552935A0 (es) Procedimiento para la produccion de d-l-amino acidos
ES552407A0 (es) Procedimiento para la fabricacion de derivados aminoalcoholes peptidicos inhibidores de la renina y de las proteasas acidas
IT1188556B (it) Amminoacido ed imminocido amminoalchilureido estere sostituito e composti estere
ES549065A0 (es) Procedimiento para la preparacion y purificacion de peptidos
NL8601011A (nl) 7-amino-3-propenylcefalosporanzuur en esters daarvan.
ES546420A0 (es) Procedimiento para la preparacion de acidos 4-isoxazolil- tiazol-2-oxamicos y sus derivados
ES545117A0 (es) Procedimiento de preparacion de nuevos derivados de acido- 9- u 11-nitroaprovincaminico racemicos y opticamente activos
MX162568A (es) Procedimiento para la preparacion de cloronitroanilinas y cloronitrofenoles
DK675688A (da) Griseolsyremonoestere samt fremgangsmaade og anvendelse deraf
IT7951108A0 (it) Procedimento per la preparazione di cloridrati di amminoacidi e biclori drati di diamminoacidi
TR22497A (tr) P-ksilel ve metonolidan tereftalik asit dimetilester uezerinden tereftalik asidin ueretilmesine mahsus usul
ES2021692B3 (es) Procedimiento para la fabricacion de n-(sulfonilmetil) formamidas e isocianuros de sulfonilmetilo.
IT1144077B (it) Carnitinammidi di amminoacidi otticamente attivi e procedimento per la loro preparazione
ES557468A0 (es) Procedimiento para preparar derivados de pirazol y bencimidazol
ES556359A0 (es) Procedimiento para la preparacion de nuevos derivados de la 2-halonicergolina y sus sales acidas complementarias.
ES545644A0 (es) Procedimiento de preparacion de acidos 1-bencil-1h-indazol -3-carboxilicos sustituidos y sus derivados
ES545378A0 (es) Procedimiento para la fabricacion de apositos grasos
MX17291A (es) Derivados del acido glutamico y procedimiento para su preparacion.