PT78623B - Process to prepare 2,4-dihydro-5-/(substituted)-phenyl/-4,4-dissubstituted-3h-pyrazol-3-ones and pharmaceutical compositions containing them - Google Patents
Process to prepare 2,4-dihydro-5-/(substituted)-phenyl/-4,4-dissubstituted-3h-pyrazol-3-ones and pharmaceutical compositions containing themInfo
- Publication number
- PT78623B PT78623B PT78623A PT7862384A PT78623B PT 78623 B PT78623 B PT 78623B PT 78623 A PT78623 A PT 78623A PT 7862384 A PT7862384 A PT 7862384A PT 78623 B PT78623 B PT 78623B
- Authority
- PT
- Portugal
- Prior art keywords
- dissubstituted
- pyrazol
- dihydro
- ones
- phenyl
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/18—One oxygen or sulfur atom
- C07D231/20—One oxygen atom attached in position 3 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/18—One oxygen or sulfur atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/497,316 US4526982A (en) | 1983-05-23 | 1983-05-23 | 2,4-Dihydro-5-[(substituted)phenyl]-4,4-disubstituted-3H-pyrazol-3-ones |
| US06/586,430 US4550119A (en) | 1983-05-23 | 1984-03-12 | 2,4-Dihydro-5-[(substituted)phenyl]-4,4-disubstituted-3H-pyrazol-3-ones |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT78623A PT78623A (en) | 1984-06-01 |
| PT78623B true PT78623B (en) | 1986-07-17 |
Family
ID=27052456
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT78623A PT78623B (en) | 1983-05-23 | 1984-05-21 | Process to prepare 2,4-dihydro-5-/(substituted)-phenyl/-4,4-dissubstituted-3h-pyrazol-3-ones and pharmaceutical compositions containing them |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4550119A (pt) |
| EP (1) | EP0126651A3 (pt) |
| KR (1) | KR840009298A (pt) |
| AU (1) | AU567345B2 (pt) |
| CA (1) | CA1215982A (pt) |
| DK (1) | DK250984A (pt) |
| ES (1) | ES8601143A1 (pt) |
| FI (1) | FI842005A (pt) |
| GR (1) | GR82359B (pt) |
| HU (1) | HU192023B (pt) |
| IL (1) | IL71841A (pt) |
| NO (1) | NO842028L (pt) |
| NZ (1) | NZ208244A (pt) |
| PH (1) | PH19768A (pt) |
| PT (1) | PT78623B (pt) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3310197A1 (de) * | 1983-03-21 | 1984-09-27 | A. Nattermann & Cie GmbH, 5000 Köln | Substituierte 3-mercapto-pyridazine und deren 3-alkylthioderivate sowie verfahren zu ihrer herstellung |
| ZA859091B (en) * | 1984-12-24 | 1987-07-29 | Warner Lambert Co | Novel 6-substituted-2 (1h)-quinolinones and related compounds having use as cardiotonic,anti-hypertensive,and anti-thrombotic agents |
| US4840955A (en) * | 1984-12-24 | 1989-06-20 | Warner-Lambert Company | 6-substituted-2(1H)-quinolinones and related compounds having use as cardiotonic, antihypertensive, and antithrombotic agents |
| GB8502267D0 (en) * | 1985-01-30 | 1985-02-27 | Pfizer Ltd | Quinolone inotropic agents |
| USRE35801E (en) * | 1985-05-20 | 1998-05-19 | Mitsubishi Chemical Corporation | Prophylactic and therapeutic composition for circulatory disorders and method of treatment |
| DK169672B1 (da) * | 1985-05-20 | 1995-01-09 | Mitsubishi Chem Ind | Farmaceutiske præparater indeholdende pyrazolonderivater som aktiv bestanddel og anvendelsen af pyrazolonderivater til fremstilling af farmaceutiske præparater |
| US4666913A (en) * | 1985-11-22 | 1987-05-19 | William H. Rorer, Inc. | Hydroxy and aminothiazolyl-benzodiazinone compounds, cardiotonic compositions including the same, and their uses |
| DK40192D0 (da) * | 1992-03-26 | 1992-03-26 | Neurosearch As | Imidazolforbindelser, deres fremstilling og anvendelse |
| RS52074B (en) | 2007-05-16 | 2012-06-30 | Nycomed Gmbh | PIRAZOLONE DERIVATED AS PDE4 INHIBITORS |
| AR074318A1 (es) | 2008-11-14 | 2011-01-05 | Nycomed Gmbh | Derivados heterociclicos de pirazolona, composiciones farmaceuticas que los contienen y uso de los mismos para el tratamiento de enfermedades de las vias respiratorias. |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL286908A (pt) * | 1961-12-19 | |||
| GB962533A (en) * | 1962-04-24 | 1964-07-01 | Imp Chemical Industi Australia | Anthelmintic compositions |
| DE2828529A1 (de) * | 1978-06-29 | 1980-01-17 | Kali Chemie Pharma Gmbh | Neue 5-phenylpyrazol-derivate, verfahren zu deren herstellung und arzneimittel |
| DK187880A (da) * | 1979-05-04 | 1980-11-05 | Continental Pharma | Fremgangsmaade til fremstilling af fenyl tylaminderivater |
| FR2479219A1 (fr) * | 1980-04-01 | 1981-10-02 | Nativelle Sa Ets | Amino-alcoxy pyrazoles, procede pour leur preparation, et medicaments les contenant |
| FR2513996A1 (fr) * | 1981-10-02 | 1983-04-08 | Nativelle Sa Ets | Derives du pyrazole, procede pour leur preparation et application en therapeutique |
-
1984
- 1984-03-12 US US06/586,430 patent/US4550119A/en not_active Expired - Fee Related
- 1984-05-03 CA CA000453446A patent/CA1215982A/en not_active Expired
- 1984-05-15 IL IL71841A patent/IL71841A/xx not_active IP Right Cessation
- 1984-05-16 KR KR1019840002637A patent/KR840009298A/ko not_active IP Right Cessation
- 1984-05-18 FI FI842005A patent/FI842005A/fi not_active Application Discontinuation
- 1984-05-21 PT PT78623A patent/PT78623B/pt unknown
- 1984-05-21 PH PH30705A patent/PH19768A/en unknown
- 1984-05-21 AU AU28440/84A patent/AU567345B2/en not_active Ceased
- 1984-05-22 NZ NZ208244A patent/NZ208244A/xx unknown
- 1984-05-22 NO NO842028A patent/NO842028L/no unknown
- 1984-05-22 DK DK250984A patent/DK250984A/da not_active Application Discontinuation
- 1984-05-22 EP EP84303456A patent/EP0126651A3/en not_active Withdrawn
- 1984-05-22 GR GR74794A patent/GR82359B/el unknown
- 1984-05-22 ES ES532689A patent/ES8601143A1/es not_active Expired
- 1984-05-22 HU HU841975A patent/HU192023B/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0126651A3 (en) | 1989-02-08 |
| ES532689A0 (es) | 1985-10-16 |
| IL71841A (en) | 1987-10-20 |
| NZ208244A (en) | 1986-10-08 |
| DK250984A (da) | 1984-11-24 |
| US4550119A (en) | 1985-10-29 |
| EP0126651A2 (en) | 1984-11-28 |
| NO842028L (no) | 1984-11-26 |
| GR82359B (pt) | 1984-12-13 |
| DK250984D0 (da) | 1984-05-22 |
| PT78623A (en) | 1984-06-01 |
| FI842005A (fi) | 1984-11-24 |
| HU192023B (en) | 1987-04-28 |
| IL71841A0 (en) | 1984-09-30 |
| HUT34971A (en) | 1985-05-28 |
| AU2844084A (en) | 1984-11-29 |
| KR840009298A (ko) | 1984-12-26 |
| PH19768A (en) | 1986-06-27 |
| CA1215982A (en) | 1986-12-30 |
| AU567345B2 (en) | 1987-11-19 |
| ES8601143A1 (es) | 1985-10-16 |
| FI842005A0 (fi) | 1984-05-18 |
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