PT76693B - (-)-15-deoxyspergualin a process for the preparation of the same an intermediate of the same and its use as medicament - Google Patents

(-)-15-deoxyspergualin a process for the preparation of the same an intermediate of the same and its use as medicament

Info

Publication number
PT76693B
PT76693B PT76693A PT7669383A PT76693B PT 76693 B PT76693 B PT 76693B PT 76693 A PT76693 A PT 76693A PT 7669383 A PT7669383 A PT 7669383A PT 76693 B PT76693 B PT 76693B
Authority
PT
Portugal
Prior art keywords
same
deoxyspergualin
medicament
preparation
compounds
Prior art date
Application number
PT76693A
Other languages
English (en)
Other versions
PT76693A (en
Original Assignee
Microbial Chem Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chem Res Found filed Critical Microbial Chem Res Found
Publication of PT76693A publication Critical patent/PT76693A/pt
Publication of PT76693B publication Critical patent/PT76693B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrane Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Phenolic Resins Or Amino Resins (AREA)
PT76693A 1982-05-17 1983-05-16 (-)-15-deoxyspergualin a process for the preparation of the same an intermediate of the same and its use as medicament PT76693B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57081398A JPS58198455A (ja) 1982-05-17 1982-05-17 (−)−15−デオキシスパガリンおよびその製造法並びにその中間体

Publications (2)

Publication Number Publication Date
PT76693A PT76693A (en) 1983-06-01
PT76693B true PT76693B (en) 1986-08-28

Family

ID=13745194

Family Applications (1)

Application Number Title Priority Date Filing Date
PT76693A PT76693B (en) 1982-05-17 1983-05-16 (-)-15-deoxyspergualin a process for the preparation of the same an intermediate of the same and its use as medicament

Country Status (10)

Country Link
EP (1) EP0094632B1 (pt)
JP (1) JPS58198455A (pt)
AT (1) ATE18203T1 (pt)
CA (1) CA1236484A (pt)
DE (1) DE3362260D1 (pt)
DK (1) DK166384C (pt)
ES (1) ES8407009A1 (pt)
GR (1) GR77478B (pt)
IE (1) IE54926B1 (pt)
PT (1) PT76693B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60120886A (ja) * 1983-12-02 1985-06-28 Takeda Chem Ind Ltd セフェムカルボン酸のナトリウム塩の結晶
JPS61129119A (ja) * 1984-11-13 1986-06-17 Microbial Chem Res Found 新規免疫抑制剤
JPS61165322A (ja) * 1985-01-14 1986-07-26 Microbial Chem Res Found スパガリン類の注射用凍結乾燥製剤
DE3626306A1 (de) * 1986-08-02 1988-02-11 Behringwerke Ag Verwendung von 15-deoxyspergualin als arzneimittel
JPH0776204B2 (ja) * 1988-07-01 1995-08-16 寳酒造株式会社 スパガリン類の精製法
US5196453A (en) * 1989-05-29 1993-03-23 Takara Shuzo Co., Ltd. Crystalline deoxyspergualin, process for its preparation and suppository containing the same
YU48230B (sh) * 1989-05-29 1997-08-22 Takara Shuzo Co.Ltd. Kristalni deoksispergvalin i postupak za njegovo pripremanje
CA2183917A1 (en) * 1995-09-26 1997-03-27 Xuebao Wang Preparation of optically active (s)-(-) and (r)-(+)- deoxyspergualin and novel intermediates thereof

Also Published As

Publication number Publication date
EP0094632B1 (en) 1986-02-26
DK166384C (da) 1993-09-27
DK166384B (da) 1993-05-10
DK217983D0 (da) 1983-05-16
ATE18203T1 (de) 1986-03-15
IE54926B1 (en) 1990-03-28
JPH0211582B2 (pt) 1990-03-14
ES522418A0 (es) 1984-08-16
IE831132L (en) 1983-11-17
ES8407009A1 (es) 1984-08-16
DK217983A (da) 1983-11-18
DE3362260D1 (en) 1986-04-03
EP0094632A1 (en) 1983-11-23
CA1236484A (en) 1988-05-10
GR77478B (pt) 1984-09-24
JPS58198455A (ja) 1983-11-18
PT76693A (en) 1983-06-01

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Legal Events

Date Code Title Description
MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19970228