DK217983A - (-)-15-deoxyspergualin, dets fremstilling og anvendelse - Google Patents
(-)-15-deoxyspergualin, dets fremstilling og anvendelse Download PDFInfo
- Publication number
- DK217983A DK217983A DK217983A DK217983A DK217983A DK 217983 A DK217983 A DK 217983A DK 217983 A DK217983 A DK 217983A DK 217983 A DK217983 A DK 217983A DK 217983 A DK217983 A DK 217983A
- Authority
- DK
- Denmark
- Prior art keywords
- deoxyspergualin
- production
- compounds
- intermediates
- medicament
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrane Compounds (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Phenolic Resins Or Amino Resins (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP57081398A JPS58198455A (ja) | 1982-05-17 | 1982-05-17 | （−）−１５−デオキシスパガリンおよびその製造法並びにその中間体 |
| JP8139882 | 1982-05-17 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK217983D0 DK217983D0 (da) | 1983-05-16 |
| DK217983A true DK217983A (da) | 1983-11-18 |
| DK166384B DK166384B (da) | 1993-05-10 |
| DK166384C DK166384C (da) | 1993-09-27 |
Family
ID=13745194
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK217983A DK166384C (da) | 1982-05-17 | 1983-05-16 | Analogifremgangsmaade til fremstilling af (-)-15-deoxyspergualing og farmaceutisk acceptable syreadditionsssalte heraf samt mellemprodukt |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0094632B1 (da) |
| JP (1) | JPS58198455A (da) |
| AT (1) | ATE18203T1 (da) |
| CA (1) | CA1236484A (da) |
| DE (1) | DE3362260D1 (da) |
| DK (1) | DK166384C (da) |
| ES (1) | ES8407009A1 (da) |
| GR (1) | GR77478B (da) |
| IE (1) | IE54926B1 (da) |
| PT (1) | PT76693B (da) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60120886A (ja) * | 1983-12-02 | 1985-06-28 | Takeda Chem Ind Ltd | セフェムカルボン酸のナトリウム塩の結晶 |
| JPS61129119A (ja) * | 1984-11-13 | 1986-06-17 | Microbial Chem Res Found | 新規免疫抑制剤 |
| JPS61165322A (ja) * | 1985-01-14 | 1986-07-26 | Microbial Chem Res Found | スパガリン類の注射用凍結乾燥製剤 |
| DE3626306A1 (de) * | 1986-08-02 | 1988-02-11 | Behringwerke Ag | Verwendung von 15-deoxyspergualin als arzneimittel |
| JPH0776204B2 (ja) * | 1988-07-01 | 1995-08-16 | 寳酒造株式会社 | スパガリン類の精製法 |
| YU48230B (sh) * | 1989-05-29 | 1997-08-22 | Takara Shuzo Co.Ltd. | Kristalni deoksispergvalin i postupak za njegovo pripremanje |
| US5196453A (en) * | 1989-05-29 | 1993-03-23 | Takara Shuzo Co., Ltd. | Crystalline deoxyspergualin, process for its preparation and suppository containing the same |
| CA2183917A1 (en) * | 1995-09-26 | 1997-03-27 | Xuebao Wang | Preparation of optically active (s)-(-) and (r)-(+)- deoxyspergualin and novel intermediates thereof |
-
1982
- 1982-05-17 JP JP57081398A patent/JPS58198455A/ja active Granted
-
1983
- 1983-05-13 DE DE8383104712T patent/DE3362260D1/de not_active Expired
- 1983-05-13 AT AT83104712T patent/ATE18203T1/de not_active IP Right Cessation
- 1983-05-13 EP EP83104712A patent/EP0094632B1/en not_active Expired
- 1983-05-16 ES ES522418A patent/ES8407009A1/es not_active Expired
- 1983-05-16 PT PT76693A patent/PT76693B/pt not_active IP Right Cessation
- 1983-05-16 IE IE1132/83A patent/IE54926B1/en not_active IP Right Cessation
- 1983-05-16 DK DK217983A patent/DK166384C/da active
- 1983-05-16 GR GR71359A patent/GR77478B/el unknown
- 1983-05-16 CA CA000428256A patent/CA1236484A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DK166384B (da) | 1993-05-10 |
| DK217983D0 (da) | 1983-05-16 |
| ATE18203T1 (de) | 1986-03-15 |
| ES522418A0 (es) | 1984-08-16 |
| PT76693A (en) | 1983-06-01 |
| GR77478B (da) | 1984-09-24 |
| EP0094632B1 (en) | 1986-02-26 |
| EP0094632A1 (en) | 1983-11-23 |
| JPH0211582B2 (da) | 1990-03-14 |
| PT76693B (en) | 1986-08-28 |
| IE54926B1 (en) | 1990-03-28 |
| ES8407009A1 (es) | 1984-08-16 |
| IE831132L (en) | 1983-11-17 |
| CA1236484A (en) | 1988-05-10 |
| DE3362260D1 (en) | 1986-04-03 |
| DK166384C (da) | 1993-09-27 |
| JPS58198455A (ja) | 1983-11-18 |
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