PT72515B - Process for preparing s-(-)-1-(tert-butylamino)-3-<(4-morpholi-no-1,2,5-thiadiazol-3-yl)-oxy>-2-propanol pamoate - Google Patents

Process for preparing s-(-)-1-(tert-butylamino)-3-<(4-morpholi-no-1,2,5-thiadiazol-3-yl)-oxy>-2-propanol pamoate

Info

Publication number
PT72515B
PT72515B PT72515A PT7251581A PT72515B PT 72515 B PT72515 B PT 72515B PT 72515 A PT72515 A PT 72515A PT 7251581 A PT7251581 A PT 7251581A PT 72515 B PT72515 B PT 72515B
Authority
PT
Portugal
Prior art keywords
thiadiazol
pamoate
butylamino
oxy
propanol
Prior art date
Application number
PT72515A
Other languages
English (en)
Portuguese (pt)
Other versions
PT72515A (en
Inventor
Martin W Henley
Richar J Harwood
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of PT72515A publication Critical patent/PT72515A/pt
Publication of PT72515B publication Critical patent/PT72515B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/10—1,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
PT72515A 1980-02-19 1981-02-17 Process for preparing s-(-)-1-(tert-butylamino)-3-<(4-morpholi-no-1,2,5-thiadiazol-3-yl)-oxy>-2-propanol pamoate PT72515B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12233880A 1980-02-19 1980-02-19

Publications (2)

Publication Number Publication Date
PT72515A PT72515A (en) 1981-03-01
PT72515B true PT72515B (en) 1982-12-20

Family

ID=22402132

Family Applications (1)

Application Number Title Priority Date Filing Date
PT72515A PT72515B (en) 1980-02-19 1981-02-17 Process for preparing s-(-)-1-(tert-butylamino)-3-<(4-morpholi-no-1,2,5-thiadiazol-3-yl)-oxy>-2-propanol pamoate

Country Status (11)

Country Link
EP (1) EP0034542B1 (enExample)
JP (1) JPS56131575A (enExample)
AT (1) ATE15193T1 (enExample)
AU (1) AU540656B2 (enExample)
DE (1) DE3171965D1 (enExample)
DK (1) DK70981A (enExample)
ES (1) ES499570A0 (enExample)
GR (1) GR74105B (enExample)
IE (1) IE50923B1 (enExample)
NZ (1) NZ196227A (enExample)
PT (1) PT72515B (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2106852T3 (es) * 1992-07-08 1997-11-16 Santen Oy Composicion oftalmica que contiene hemihidrato de timolol.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3657237A (en) * 1968-05-22 1972-04-18 Frosst & Co Charles E Process for making 1 2 5-thiadiazoles in the sinister configuration
GB1253709A (en) * 1968-05-22 1971-11-17 Frosst & Co Charles E Thiadiazole derivatives
US3833727A (en) * 1972-03-06 1974-09-03 Merck & Co Inc Hydralazine and beta-adrenergic blocking agent compositions for treating hypertension
GB1429420A (en) * 1974-06-05 1976-03-24 Merck Sharp & Dohme Thiadiazole derivatives
DE2428030A1 (de) * 1974-06-11 1976-01-02 Merck Sharp & Dohme Substituierte thiadiazole und verfahren zu ihrer herstellung
CH597209A5 (en) * 1974-06-18 1978-03-31 Merck Sharp & Dohme 4-(3-Amino-2-acyloxypropoxyl)-1,2,5-thiadiazoles
FR2277581A1 (fr) * 1974-07-09 1976-02-06 Merck Sharp & Dohme Thiadiazoles substitues et procede pour leur preparation

Also Published As

Publication number Publication date
AU6713181A (en) 1981-08-27
ES8205795A1 (es) 1982-07-01
EP0034542A2 (en) 1981-08-26
AU540656B2 (en) 1984-11-29
EP0034542B1 (en) 1985-08-28
ES499570A0 (es) 1982-07-01
EP0034542A3 (en) 1981-10-21
GR74105B (enExample) 1984-06-06
NZ196227A (en) 1984-09-28
IE50923B1 (en) 1986-08-20
JPS56131575A (en) 1981-10-15
DE3171965D1 (en) 1985-10-03
DK70981A (da) 1981-08-20
PT72515A (en) 1981-03-01
ATE15193T1 (de) 1985-09-15
IE810310L (en) 1981-08-19

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Effective date: 19940621