ES499570A0 - Un procedimiento para la preparacion de una composicion oftalmica de s-(-)-1-(t-butilmino)-3-((4-morfolino-1,2,5,-tiadiazol-3-il)oxi)-2-propanol. - Google Patents

Un procedimiento para la preparacion de una composicion oftalmica de s-(-)-1-(t-butilmino)-3-((4-morfolino-1,2,5,-tiadiazol-3-il)oxi)-2-propanol.

Info

Publication number
ES499570A0
ES499570A0 ES499570A ES499570A ES499570A0 ES 499570 A0 ES499570 A0 ES 499570A0 ES 499570 A ES499570 A ES 499570A ES 499570 A ES499570 A ES 499570A ES 499570 A0 ES499570 A0 ES 499570A0
Authority
ES
Spain
Prior art keywords
propanol
butilmino
tiadiazol
morfolino
oxi
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES499570A
Other languages
English (en)
Other versions
ES8205795A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES8205795A1 publication Critical patent/ES8205795A1/es
Publication of ES499570A0 publication Critical patent/ES499570A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/10—1,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Cephalosporin Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
ES499570A 1980-02-19 1981-02-18 Un procedimiento para la preparacion de una composicion oftalmica de s-(-)-1-(t-butilmino)-3-((4-morfolino-1,2,5,-tiadiazol-3-il)oxi)-2-propanol. Granted ES499570A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12233880A 1980-02-19 1980-02-19

Publications (2)

Publication Number Publication Date
ES8205795A1 ES8205795A1 (es) 1982-07-01
ES499570A0 true ES499570A0 (es) 1982-07-01

Family

ID=22402132

Family Applications (1)

Application Number Title Priority Date Filing Date
ES499570A Granted ES499570A0 (es) 1980-02-19 1981-02-18 Un procedimiento para la preparacion de una composicion oftalmica de s-(-)-1-(t-butilmino)-3-((4-morfolino-1,2,5,-tiadiazol-3-il)oxi)-2-propanol.

Country Status (11)

Country Link
EP (1) EP0034542B1 (es)
JP (1) JPS56131575A (es)
AT (1) ATE15193T1 (es)
AU (1) AU540656B2 (es)
DE (1) DE3171965D1 (es)
DK (1) DK70981A (es)
ES (1) ES499570A0 (es)
GR (1) GR74105B (es)
IE (1) IE50923B1 (es)
NZ (1) NZ196227A (es)
PT (1) PT72515B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE154513T1 (de) * 1992-07-08 1997-07-15 Leiras Oy Augenarzneimittel enthaltend timolol hemihydrat

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1253709A (en) * 1968-05-22 1971-11-17 Frosst & Co Charles E Thiadiazole derivatives
US3657237A (en) * 1968-05-22 1972-04-18 Frosst & Co Charles E Process for making 1 2 5-thiadiazoles in the sinister configuration
US3833727A (en) * 1972-03-06 1974-09-03 Merck & Co Inc Hydralazine and beta-adrenergic blocking agent compositions for treating hypertension
GB1429420A (en) * 1974-06-05 1976-03-24 Merck Sharp & Dohme Thiadiazole derivatives
DE2428030A1 (de) * 1974-06-11 1976-01-02 Merck Sharp & Dohme Substituierte thiadiazole und verfahren zu ihrer herstellung
CH597209A5 (en) * 1974-06-18 1978-03-31 Merck Sharp & Dohme 4-(3-Amino-2-acyloxypropoxyl)-1,2,5-thiadiazoles
FR2277581A1 (fr) * 1974-07-09 1976-02-06 Merck Sharp & Dohme Thiadiazoles substitues et procede pour leur preparation

Also Published As

Publication number Publication date
IE810310L (en) 1981-08-19
AU6713181A (en) 1981-08-27
GR74105B (es) 1984-06-06
EP0034542A3 (en) 1981-10-21
IE50923B1 (en) 1986-08-20
PT72515A (en) 1981-03-01
NZ196227A (en) 1984-09-28
DE3171965D1 (en) 1985-10-03
ATE15193T1 (de) 1985-09-15
ES8205795A1 (es) 1982-07-01
AU540656B2 (en) 1984-11-29
DK70981A (da) 1981-08-20
EP0034542A2 (en) 1981-08-26
EP0034542B1 (en) 1985-08-28
PT72515B (en) 1982-12-20
JPS56131575A (en) 1981-10-15

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970519