PT72107B - Procede de preparation d'un complexe hydrosoluble de alpha-6-dioxi-5-hydroxitetracycline et de tetrametaphosphate desodium - Google Patents
Procede de preparation d'un complexe hydrosoluble de alpha-6-dioxi-5-hydroxitetracycline et de tetrametaphosphate desodiumInfo
- Publication number
- PT72107B PT72107B PT72107A PT7210780A PT72107B PT 72107 B PT72107 B PT 72107B PT 72107 A PT72107 A PT 72107A PT 7210780 A PT7210780 A PT 7210780A PT 72107 B PT72107 B PT 72107B
- Authority
- PT
- Portugal
- Prior art keywords
- hydroxitetracycline
- desodium
- dioxi
- tetrametaphosphate
- alpha
- Prior art date
Links
- GIXFALHDORQSOQ-UHFFFAOYSA-J 2,4,6,8-tetraoxido-1,3,5,7,2$l^{5},4$l^{5},6$l^{5},8$l^{5}-tetraoxatetraphosphocane 2,4,6,8-tetraoxide Chemical compound [O-]P1(=O)OP([O-])(=O)OP([O-])(=O)OP([O-])(=O)O1 GIXFALHDORQSOQ-UHFFFAOYSA-J 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/42—Phosphorus; Compounds thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
- C07C237/26—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
- C07F1/04—Sodium compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PT72107A PT72107B (fr) | 1980-11-25 | 1980-11-25 | Procede de preparation d'un complexe hydrosoluble de alpha-6-dioxi-5-hydroxitetracycline et de tetrametaphosphate desodium |
| ZA817804A ZA817804B (en) | 1980-11-25 | 1981-11-11 | Process for the preparation of a water soluble complex of alpha-6-deoxy-5-hydroxytetracycline and of sodium tetrametaphosphate |
| AU77612/81A AU543041B2 (en) | 1980-11-25 | 1981-11-18 | Alpha-6-deoxy-5-hydroxytetracycline sodium tetrameta- phosphate complex |
| KR1019810004468A KR860000450B1 (ko) | 1980-11-25 | 1981-11-19 | α-6-데옥씨-5-하이드록씨 테트라 싸이클린과 소듐 테트라메타포스 페이트의 수용성 복합체의 제조방법 |
| ES507293A ES8302629A1 (es) | 1980-11-25 | 1981-11-19 | Proceso de preparacion de un complejo soluble en agua de al-fa-6-desoxi-5-hidroxitetraciclina y sodio tetrametafosfato. |
| PH26527A PH20236A (en) | 1980-11-25 | 1981-11-20 | Process of oreoaration of a water soluble complex of 0(-6-deoxy-5-hydroxytetracyline and sodium tetrametaphoshate |
| DE19813146279 DE3146279A1 (de) | 1980-11-25 | 1981-11-21 | Verfahren zur herstellung eines wasserloeslichen komplexes aus (alpha)-6-desoxy-5-hydroxytetracyclin und natriumtetrametaphosphat |
| FR8121887A FR2494685A1 (fr) | 1980-11-25 | 1981-11-23 | Complexes d'a-6-desoxy-5-hydroxytetracycline et de tetrametaphosphate de sodium solubles dans l'eau, leur preparation et leur utilisation |
| BE0/206644A BE891236A (fr) | 1980-11-25 | 1981-11-24 | Complexes d'alpha-6-desoxy-5-hydroxytetracycline et de tetrametaphosphate de sodium solubles dans l'eau, leur preparation et leur utilisation |
| NLAANVRAGE8105309,A NL190067C (nl) | 1980-11-25 | 1981-11-24 | Werkwijze voor de bereiding van een in water oplosbaar complex van alfa-6-deoxy-5-hydroxytetracycline en natriumtetrametafosfaat. |
| JP56187068A JPS57116033A (en) | 1980-11-25 | 1981-11-24 | Lower alcohol-water solvation of sodium tetrametaphosphate complex of alpha-6-deoxy- hydroxytetracycline and manufacture |
| GB8135611A GB2088864B (en) | 1980-11-25 | 1981-11-25 | Doxycycline monosodium tetrametaphosphate complexes and their preparation |
| HK106/87A HK10687A (en) | 1980-11-25 | 1987-01-28 | Doxycycline monosodium tetrametaphosphate complexes and their preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PT72107A PT72107B (fr) | 1980-11-25 | 1980-11-25 | Procede de preparation d'un complexe hydrosoluble de alpha-6-dioxi-5-hydroxitetracycline et de tetrametaphosphate desodium |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT72107A PT72107A (fr) | 1980-12-01 |
| PT72107B true PT72107B (fr) | 1981-10-28 |
Family
ID=20082809
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT72107A PT72107B (fr) | 1980-11-25 | 1980-11-25 | Procede de preparation d'un complexe hydrosoluble de alpha-6-dioxi-5-hydroxitetracycline et de tetrametaphosphate desodium |
Country Status (13)
| Country | Link |
|---|---|
| JP (1) | JPS57116033A (nl) |
| KR (1) | KR860000450B1 (nl) |
| AU (1) | AU543041B2 (nl) |
| BE (1) | BE891236A (nl) |
| DE (1) | DE3146279A1 (nl) |
| ES (1) | ES8302629A1 (nl) |
| FR (1) | FR2494685A1 (nl) |
| GB (1) | GB2088864B (nl) |
| HK (1) | HK10687A (nl) |
| NL (1) | NL190067C (nl) |
| PH (1) | PH20236A (nl) |
| PT (1) | PT72107B (nl) |
| ZA (1) | ZA817804B (nl) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5538954A (en) * | 1994-06-24 | 1996-07-23 | A/S Dumex (Dumex Ltd.) | Salts of tetracyclines |
| NZ544826A (en) | 2003-07-25 | 2008-07-31 | Warner Chilcott Co Inc | A doxycycline metal complex in a solid dosage form |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1068701B (de) * | 1959-11-12 | Bristol Laboratories Inc., East Syracuse, N. Y. (V. St. A.) | Verfahren zur Herstellung von antibiotisch wirksamem Tetracyclinnatriumhexametaphosphat | |
| BE568762A (nl) * | ||||
| US2791609A (en) * | 1956-09-27 | 1957-05-07 | Murray A Kaplan | Tetracycline metallo-phosphate complexes and method preparation |
| US2795528A (en) * | 1956-10-24 | 1957-06-11 | Frank H Buckwalter | Therapeutic composition containing a tetracycline and a phosphate other than orthophosphate |
| US3053892A (en) * | 1960-04-27 | 1962-09-11 | American Cyanamid Co | Metaphosphoric acid complexes of tetracycline and its analogs |
| US3068264A (en) * | 1961-06-06 | 1962-12-11 | American Cyanamid Co | Tetracycline antibiotic-aluminumphosphoric acid complexes |
| GB1180701A (en) * | 1967-06-23 | 1970-02-11 | Pfizer & Co C | Process for Purifying Tetracycline Antibiotics with Phosphate Salts |
| ES396132A1 (es) * | 1970-10-30 | 1972-12-01 | Villax | Proceso de preparacion de los complejos del acido metafos- forico de la alfa-6-deoxi-5-hidroxitetraciclina y las sales alcali-metalicas de los mismos. |
| JPS5745215A (en) * | 1980-09-01 | 1982-03-15 | Toshiba Corp | Molding device of iron plate for wound core |
-
1980
- 1980-11-25 PT PT72107A patent/PT72107B/pt unknown
-
1981
- 1981-11-11 ZA ZA817804A patent/ZA817804B/xx unknown
- 1981-11-18 AU AU77612/81A patent/AU543041B2/en not_active Ceased
- 1981-11-19 ES ES507293A patent/ES8302629A1/es not_active Expired
- 1981-11-19 KR KR1019810004468A patent/KR860000450B1/ko active
- 1981-11-20 PH PH26527A patent/PH20236A/en unknown
- 1981-11-21 DE DE19813146279 patent/DE3146279A1/de not_active Withdrawn
- 1981-11-23 FR FR8121887A patent/FR2494685A1/fr active Granted
- 1981-11-24 NL NLAANVRAGE8105309,A patent/NL190067C/nl not_active IP Right Cessation
- 1981-11-24 BE BE0/206644A patent/BE891236A/fr not_active IP Right Cessation
- 1981-11-24 JP JP56187068A patent/JPS57116033A/ja active Pending
- 1981-11-25 GB GB8135611A patent/GB2088864B/en not_active Expired
-
1987
- 1987-01-28 HK HK106/87A patent/HK10687A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES507293A0 (es) | 1983-02-01 |
| GB2088864A (en) | 1982-06-16 |
| BE891236A (fr) | 1982-05-24 |
| NL8105309A (nl) | 1982-06-16 |
| FR2494685B1 (nl) | 1985-02-01 |
| KR830007076A (ko) | 1983-10-14 |
| PT72107A (fr) | 1980-12-01 |
| PH20236A (en) | 1986-11-10 |
| KR860000450B1 (ko) | 1986-04-26 |
| HK10687A (en) | 1987-02-06 |
| NL190067C (nl) | 1993-10-18 |
| NL190067B (nl) | 1993-05-17 |
| DE3146279A1 (de) | 1982-08-19 |
| ES8302629A1 (es) | 1983-02-01 |
| AU543041B2 (en) | 1985-03-28 |
| FR2494685A1 (fr) | 1982-05-28 |
| GB2088864B (en) | 1984-09-12 |
| ZA817804B (en) | 1982-12-29 |
| JPS57116033A (en) | 1982-07-19 |
| AU7761281A (en) | 1982-06-03 |
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