PT71861B - Process for preparing long lasting agonists and agonists of lhrh - Google Patents
Process for preparing long lasting agonists and agonists of lhrhInfo
- Publication number
- PT71861B PT71861B PT71861A PT7186180A PT71861B PT 71861 B PT71861 B PT 71861B PT 71861 A PT71861 A PT 71861A PT 7186180 A PT7186180 A PT 7186180A PT 71861 B PT71861 B PT 71861B
- Authority
- PT
- Portugal
- Prior art keywords
- sub
- amino acid
- agonists
- alkyl
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/13—Luteinizing hormone-releasing hormone; related peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Diabetes (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/080,844 US4377515A (en) | 1979-10-01 | 1979-10-01 | Long lasting agonists and antagonists of LH-RH |
Publications (2)
Publication Number | Publication Date |
---|---|
PT71861A PT71861A (en) | 1980-11-01 |
PT71861B true PT71861B (en) | 1982-03-31 |
Family
ID=22159985
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT71861A PT71861B (en) | 1979-10-01 | 1980-10-01 | Process for preparing long lasting agonists and agonists of lhrh |
Country Status (10)
Country | Link |
---|---|
US (1) | US4377515A (pt) |
EP (1) | EP0026640B1 (pt) |
JP (1) | JPS56115753A (pt) |
AT (1) | ATE6638T1 (pt) |
DE (1) | DE3067002D1 (pt) |
DK (1) | DK413580A (pt) |
ES (1) | ES8200080A1 (pt) |
GR (1) | GR70026B (pt) |
IE (1) | IE50298B1 (pt) |
PT (1) | PT71861B (pt) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT73522B (en) * | 1980-08-18 | 1983-07-14 | Merck & Co Inc | Process for preparing substituted caprylolactam derivatives as antihypertensives |
GR74635B (pt) * | 1980-08-18 | 1984-06-29 | Merck & Co Inc | |
IL63540A0 (en) * | 1980-08-18 | 1981-11-30 | Merck & Co Inc | Substituted enantholactam derivatives as antihypertensives |
US4410520A (en) * | 1981-11-09 | 1983-10-18 | Ciba-Geigy Corporation | 3-Amino-[1]-benzazepin-2-one-1-alkanoic acids |
US4410807A (en) * | 1982-03-26 | 1983-10-18 | Kay Industries, Inc. | Regulating device for polyphase electrical circuits |
US4473575A (en) * | 1982-07-19 | 1984-09-25 | Ciba-Geigy Corporation | 3-Amino-(1)-benzazepin-2-one-1-alkanoic acids |
IT1178775B (it) * | 1983-12-23 | 1987-09-16 | Konzponti Valto Es Hitelbank R | Derivati della gonadoliberina e procedimento per la loro preparazione |
US4659691A (en) * | 1985-02-08 | 1987-04-21 | Merck & Co., Inc. | Novel cyclic Hexapeptide LHRH antagonists |
US4677193A (en) * | 1985-02-22 | 1987-06-30 | The Salk Institute For Biological Studies | Peptides containing an aliphatic-aromatic ketone side chain |
HU194280B (en) * | 1985-10-22 | 1988-01-28 | Richter Gedeon Vegyeszet | Process for producing new gonadoliberin analogues of high effectivity and pharmaceutical compositions containing them |
HU194913B (en) * | 1986-01-03 | 1988-03-28 | Innofinance Altalanos Innovaci | Process for producing novel gonadoliberin derivatives containing in the sixth position aromatic amino carboxylic acid and medical preparations containing these compounds |
US4762717A (en) * | 1986-03-21 | 1988-08-09 | The General Hospital Corporation | Continuous delivery of luteinizing hormone releasing hormone compositions in combination with sex steroid delivery for use as a contraceptive |
US4761398A (en) * | 1986-08-18 | 1988-08-02 | Embrex, Inc. | Method of inducing birds to molt |
WO1989009226A1 (en) * | 1988-03-28 | 1989-10-05 | National Research Development Corporation | Peptides |
GB8807427D0 (en) * | 1988-03-28 | 1988-05-05 | National Biological Standards Board | Peptides |
US5942489A (en) * | 1996-05-03 | 1999-08-24 | The Administrators Of The Tulane Educational Fund | HGH-RH(1-29)NH2 analogues having antagonistic activity |
EP0842946A1 (en) * | 1996-11-14 | 1998-05-20 | Laboratoire Theramex S.A. | Conformationally constrained LH-RH analogues, their uses and pharmaceutical compositions containing them |
GB9809021D0 (en) | 1998-04-29 | 1998-06-24 | Zeneca Ltd | Chemical process |
DE19841895A1 (de) * | 1998-09-11 | 2000-03-23 | Degussa | Neues Verfahren zur Herstellung von 3-Amino-2-oxo-pyrrolidinen, neue Zwischenprodukte und deren Verwendung |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS50142563A (pt) * | 1974-04-26 | 1975-11-17 | ||
DE2617646C2 (de) * | 1976-04-22 | 1986-07-31 | Hoechst Ag, 6230 Frankfurt | Nonapeptid-amide und Decapeptid-amide mit Gonadoliberin-Wirkung, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate |
-
1979
- 1979-10-01 US US06/080,844 patent/US4377515A/en not_active Expired - Lifetime
-
1980
- 1980-09-25 EP EP80303370A patent/EP0026640B1/en not_active Expired
- 1980-09-25 AT AT80303370T patent/ATE6638T1/de not_active IP Right Cessation
- 1980-09-25 DE DE8080303370T patent/DE3067002D1/de not_active Expired
- 1980-09-29 GR GR62988A patent/GR70026B/el unknown
- 1980-09-30 DK DK413580A patent/DK413580A/da not_active Application Discontinuation
- 1980-09-30 IE IE2039/80A patent/IE50298B1/en unknown
- 1980-09-30 ES ES495517A patent/ES8200080A1/es not_active Expired
- 1980-10-01 PT PT71861A patent/PT71861B/pt unknown
- 1980-10-01 JP JP13751380A patent/JPS56115753A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
IE50298B1 (en) | 1986-03-19 |
JPS6210519B2 (pt) | 1987-03-06 |
ES495517A0 (es) | 1981-10-16 |
EP0026640A2 (en) | 1981-04-08 |
PT71861A (en) | 1980-11-01 |
EP0026640A3 (en) | 1981-08-05 |
EP0026640B1 (en) | 1984-03-14 |
ATE6638T1 (de) | 1984-03-15 |
US4377515A (en) | 1983-03-22 |
GR70026B (pt) | 1982-07-23 |
DE3067002D1 (en) | 1984-04-19 |
DK413580A (da) | 1981-04-02 |
JPS56115753A (en) | 1981-09-11 |
IE802039L (en) | 1981-04-01 |
ES8200080A1 (es) | 1981-10-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PT71861A (en) | Process for preparing long lasting agonists and agonists of lhrh | |
ATE137763T1 (de) | Peptid-verbindungen, deren verfahren zur herstellung und sie enthaltende pharmazeutische zusammensetzung | |
CA2296036A1 (en) | Dolastatin 15 derivatives | |
ATE98651T1 (de) | Peptide mit tachykininantagonistischer aktivitaet, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate. | |
ES2137998T3 (es) | Nuevos derivados de aminoacidos, procedimiento para su preparacion y composiciones farmaceuticas que contienen estos compuestos. | |
DE69030206D1 (de) | Pyrazolopyridinverbindungen und Verfahren zu ihrer Herstellung | |
ES2158814A1 (es) | Antagonistas iii del receptor ccr-3. | |
ES2095283T3 (es) | Compuestos peptidicos, procedimiento para su preparacion y composicion farmaceutica que los contiene. | |
CA2060034A1 (en) | Tumour growth-inhibiting somatostatin analogues, pharmaceutical compositions containing them and process for preparing same | |
HUT65188A (en) | Process for preparing cyclopentane and cyclopentene-beta-aminoacids and pharmaceutical compositions containing them as active agent | |
ATE48001T1 (de) | Cephemverbindungen, verfahren zu ihrer herstellung und ihre pharmazeutischen praeparate. | |
HUT53664A (en) | Process for producing enzyme inhibiting amino acid derivatives and pharmaceutical compositions comprising such compounds as active ingredient | |
GR851467B (pt) | ||
ATE74924T1 (de) | N-(vinblastinoyl-23)-derivate von 1aminomethylposphons|ure, verfahren zu ihrer herstellung und sie enthaltende arzneimittel. | |
BR9301436A (pt) | Peptideo,processo para a sua preparacao,aplicacao desse peptideo e agente farmaceutico | |
DE68927554D1 (de) | Cephalosporinverbindungen und Verfahren zu ihrer Herstellung | |
IL86722A (en) | Guanidine-related compounds comprising a tetraphenylborate ion and their preparation | |
EA199900688A1 (ru) | Хиноксалиндионы | |
ATE19472T1 (de) | Verwendung von 5-phenyl-1,4-benzodoazepinen zur herstellung von analgetisch wirksamen pharmazeutischen zubereitungen. | |
KR970701732A (ko) | 펩신 방출을 억제하기 위한 펩티드(Peptides Inhibiting the Release of Pepsin) | |
ES8305307A1 (es) | Un procedimiento para la preparacion de un aciltripeptido. | |
AU570820B2 (en) | 1-(n-(alpha-amino-alpha-methylacetyl)-4-aminophenyl)-2- aminopropanone derivatives | |
ES8502081A1 (es) | Un procedimiento para la preparacion de un derivado de peptidos ciclicos a-21978c. | |
RU95117981A (ru) | Производные пептида, смесь их изомеров или отдельные изомеры и их терапевтически приемлемые соли, способ их получения, косметическая и фармацевтическая композиции с антивирусной активностью |