PT71598A - Process for preparing n-aminoalkyl -indol derivatives - Google Patents
Process for preparing n-aminoalkyl -indol derivativesInfo
- Publication number
- PT71598A PT71598A PT71598A PT7159880A PT71598A PT 71598 A PT71598 A PT 71598A PT 71598 A PT71598 A PT 71598A PT 7159880 A PT7159880 A PT 7159880A PT 71598 A PT71598 A PT 71598A
- Authority
- PT
- Portugal
- Prior art keywords
- alkyl
- group
- carbon atoms
- carbonyl group
- compounds
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- -1 hydroxy carbonyl group Chemical group 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000001424 substituent group Chemical group 0.000 abstract 3
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- SIKJAQJRHWYJAI-UHFFFAOYSA-N benzopyrrole Natural products C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 230000002349 favourable effect Effects 0.000 abstract 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 abstract 1
- RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 abstract 1
- 230000004899 motility Effects 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19792931323 DE2931323A1 (de) | 1979-08-02 | 1979-08-02 | Neue n-aminoalkylindol-derivate und ihre salze |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT71598A true PT71598A (en) | 1980-08-01 |
Family
ID=6077414
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT71598A PT71598A (en) | 1979-08-02 | 1980-07-24 | Process for preparing n-aminoalkyl -indol derivatives |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4374846A (en, 2012) |
| EP (1) | EP0025501B1 (en, 2012) |
| JP (1) | JPS5626873A (en, 2012) |
| AT (1) | ATE2143T1 (en, 2012) |
| AU (1) | AU535961B2 (en, 2012) |
| CA (1) | CA1145747A (en, 2012) |
| DD (1) | DD153686A5 (en, 2012) |
| DE (2) | DE2931323A1 (en, 2012) |
| DK (1) | DK333480A (en, 2012) |
| ES (1) | ES493276A0 (en, 2012) |
| FI (1) | FI802383A7 (en, 2012) |
| GR (1) | GR69359B (en, 2012) |
| HU (1) | HU180371B (en, 2012) |
| IL (1) | IL60584A (en, 2012) |
| NO (1) | NO802323L (en, 2012) |
| NZ (1) | NZ194330A (en, 2012) |
| PT (1) | PT71598A (en, 2012) |
| SU (2) | SU1119606A3 (en, 2012) |
| YU (1) | YU193780A (en, 2012) |
| ZA (1) | ZA804549B (en, 2012) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3131527A1 (de) * | 1981-08-08 | 1983-02-24 | Kali-Chemie Pharma Gmbh, 3000 Hannover | 1-phenyl-2-aminocarbonylindol-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| US4780477A (en) * | 1985-06-08 | 1988-10-25 | Kissei Pharmaceutical Co., Ltd. | Isatin compositions having anti-ulcer activities |
| EP0789688A4 (en) * | 1995-09-01 | 1997-11-19 | Lilly Co Eli | INDOLYLATED NEUROPEPTIDE Y RECEPTOR ANTAGONISTS |
| GB9523999D0 (en) | 1995-11-23 | 1996-01-24 | Lilly Co Eli | Indolyl neuropeptide y receptor antagonists |
| JP2010535816A (ja) * | 2007-08-10 | 2010-11-25 | ハー・ルンドベック・アクチエゼルスカベット | ヘテロアリールアミド類似体 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK96884C (da) | 1959-09-14 | 1963-09-16 | Dumex Ltd As | Fremgangsmåde til fremstilling af indolderivater eller salte heraf. |
| US3198807A (en) * | 1961-07-25 | 1965-08-03 | Substitutes carboxamide indoles and indolines | |
| DE1720033A1 (de) * | 1966-03-02 | 1971-05-19 | Yoshitomi Pharmaceutical | Neue Indolderivate und Verfahren zu ihrer Herstellung |
| FR2354766A1 (fr) | 1976-06-17 | 1978-01-13 | Labaz | Derives n-aminoalkyles d'indole et procedes pour les preparer |
-
1979
- 1979-08-02 DE DE19792931323 patent/DE2931323A1/de not_active Withdrawn
-
1980
- 1980-06-25 SU SU802936511A patent/SU1119606A3/ru active
- 1980-07-10 ES ES493276A patent/ES493276A0/es active Granted
- 1980-07-11 NZ NZ194330A patent/NZ194330A/xx unknown
- 1980-07-14 IL IL60584A patent/IL60584A/xx unknown
- 1980-07-14 AU AU60388/80A patent/AU535961B2/en not_active Ceased
- 1980-07-24 US US06/172,023 patent/US4374846A/en not_active Expired - Lifetime
- 1980-07-24 PT PT71598A patent/PT71598A/pt unknown
- 1980-07-28 ZA ZA00804549A patent/ZA804549B/xx unknown
- 1980-07-29 HU HU80801888A patent/HU180371B/hu unknown
- 1980-07-29 DE DE8080104465T patent/DE3061506D1/de not_active Expired
- 1980-07-29 EP EP80104465A patent/EP0025501B1/de not_active Expired
- 1980-07-29 AT AT80104465T patent/ATE2143T1/de active
- 1980-07-30 DD DD80222972A patent/DD153686A5/de unknown
- 1980-07-30 FI FI802383A patent/FI802383A7/fi not_active Application Discontinuation
- 1980-07-30 CA CA000357343A patent/CA1145747A/en not_active Expired
- 1980-07-31 GR GR62577A patent/GR69359B/el unknown
- 1980-07-31 JP JP10442980A patent/JPS5626873A/ja active Granted
- 1980-07-31 YU YU01937/80A patent/YU193780A/xx unknown
- 1980-08-01 NO NO802323A patent/NO802323L/no unknown
- 1980-08-01 DK DK333480A patent/DK333480A/da unknown
-
1982
- 1982-08-04 SU SU823472455A patent/SU1131468A3/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| AU535961B2 (en) | 1984-04-12 |
| DE3061506D1 (en) | 1983-02-03 |
| NO802323L (no) | 1981-02-03 |
| ZA804549B (en) | 1981-07-29 |
| ES8104225A1 (es) | 1981-04-16 |
| ES493276A0 (es) | 1981-04-16 |
| AU6038880A (en) | 1981-02-05 |
| SU1119606A3 (ru) | 1984-10-15 |
| NZ194330A (en) | 1982-08-17 |
| FI802383A7 (fi) | 1981-01-01 |
| EP0025501A1 (de) | 1981-03-25 |
| DK333480A (da) | 1981-02-03 |
| JPS6317828B2 (en, 2012) | 1988-04-15 |
| DE2931323A1 (de) | 1981-02-26 |
| YU193780A (en) | 1983-06-30 |
| CA1145747A (en) | 1983-05-03 |
| HU180371B (en) | 1983-02-28 |
| IL60584A0 (en) | 1980-09-16 |
| SU1131468A3 (ru) | 1984-12-23 |
| ATE2143T1 (de) | 1983-01-15 |
| JPS5626873A (en) | 1981-03-16 |
| IL60584A (en) | 1983-09-30 |
| DD153686A5 (de) | 1982-01-27 |
| GR69359B (en, 2012) | 1982-05-20 |
| EP0025501B1 (de) | 1982-12-29 |
| US4374846A (en) | 1983-02-22 |
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