PT693940E - Genes hibridos para utilizacao na producao de celulas t citotoxicas independentes de th - Google Patents
Genes hibridos para utilizacao na producao de celulas t citotoxicas independentes de thInfo
- Publication number
- PT693940E PT693940E PT94914020T PT94914020T PT693940E PT 693940 E PT693940 E PT 693940E PT 94914020 T PT94914020 T PT 94914020T PT 94914020 T PT94914020 T PT 94914020T PT 693940 E PT693940 E PT 693940E
- Authority
- PT
- Portugal
- Prior art keywords
- cells
- lymphocyte
- activated
- stimulatory factor
- production
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/525—Tumour necrosis factor [TNF]
- C07K14/5255—Lymphotoxin [LT]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5403—IL-3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/55—IL-2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/57—IFN-gamma
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70521—CD28, CD152
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
- C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4453993A | 1993-04-06 | 1993-04-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT693940E true PT693940E (pt) | 2003-03-31 |
Family
ID=21932948
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT94914020T PT693940E (pt) | 1993-04-06 | 1994-04-04 | Genes hibridos para utilizacao na producao de celulas t citotoxicas independentes de th |
Country Status (11)
Country | Link |
---|---|
US (2) | US5874556A (pt) |
EP (1) | EP0693940B1 (pt) |
JP (1) | JPH08510901A (pt) |
AT (1) | ATE227772T1 (pt) |
AU (1) | AU695615B2 (pt) |
CA (1) | CA2159898A1 (pt) |
DE (1) | DE69431715T2 (pt) |
DK (1) | DK0693940T3 (pt) |
ES (1) | ES2186685T3 (pt) |
PT (1) | PT693940E (pt) |
WO (1) | WO1994022489A1 (pt) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040063652A1 (en) * | 1988-03-21 | 2004-04-01 | Jolly Douglas J. | Combination gene delivery vehicles |
CA2204183A1 (en) * | 1994-11-01 | 1996-05-09 | Andrew Lawrence Feldhaus | Chimeric receptors for the generation of selectively-activatable th-independent cytotoxic t cells |
JPH11503916A (ja) * | 1995-04-20 | 1999-04-06 | カイロン コーポレイション | 高力価組換えレトロウイルス調製物による細胞の高効率エクスビボ形質導入 |
US6759237B1 (en) * | 1998-11-05 | 2004-07-06 | The Trustees Of The University Of Pennsylvania | Adeno-associated virus serotype 1 nucleic acid sequences, vectors and host cells containing same |
US6491907B1 (en) | 1998-11-10 | 2002-12-10 | The University Of North Carolina At Chapel Hill | Recombinant parvovirus vectors and method of making |
KR100528034B1 (ko) * | 2001-11-22 | 2005-11-22 | 메디제네스(주) | 인터루킨-2 유전자가 도입된 림포카인 활성 살해세포 |
US7381405B2 (en) * | 2002-10-15 | 2008-06-03 | The United States Of America As Represented By The Department Of Health And Human Services | Methods of preparing lymphocytes that express interleukin-2 and their use in the treatment of cancer |
WO2004034789A1 (en) * | 2002-10-15 | 2004-04-29 | The Government Of The United States Of America Represented By The Secretary Department Of Health And Human Services | Methods of preparing lymphocytes that express interleukin-2 and their use in the treatment of cancer |
NZ555830A (en) * | 2004-12-15 | 2009-01-31 | Univ North Carolina | Chimeric vectors |
KR101133185B1 (ko) * | 2008-07-29 | 2012-04-06 | 서울대학교병원 | 자연살해세포의 증식방법 |
EP2396343B1 (en) | 2009-02-11 | 2017-05-17 | The University of North Carolina At Chapel Hill | Modified virus vectors and methods of making and using the same |
US20140037599A1 (en) * | 2012-08-03 | 2014-02-06 | The Trustees Of The University Of Pennsylvania | Compositions and Methods of Treating T Cell Deficiency |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2092548A1 (en) * | 1990-09-28 | 1992-03-29 | Philip D. Greenberg | Method for producing th-independent cytotoxic t lymphocytes |
US5470730A (en) * | 1990-09-28 | 1995-11-28 | Immunex | Method for producing TH -independent cytotoxic T lymphocytes |
CA2096222C (en) | 1990-11-13 | 1998-12-29 | Stephen D. Lupton | Bifunctional selectable fusion genes |
US5272082A (en) * | 1992-03-30 | 1993-12-21 | The Wistar Institute Of Anatomy & Biology | Cytotoxic T-ALL cell lines and uses therefor |
CA2168202A1 (en) * | 1993-07-30 | 1995-03-16 | Joseph Dougherty | Efficient gene transfer into primary lymphocytes |
-
1994
- 1994-04-04 ES ES94914020T patent/ES2186685T3/es not_active Expired - Lifetime
- 1994-04-04 DK DK94914020T patent/DK0693940T3/da active
- 1994-04-04 PT PT94914020T patent/PT693940E/pt unknown
- 1994-04-04 AU AU66248/94A patent/AU695615B2/en not_active Ceased
- 1994-04-04 EP EP94914020A patent/EP0693940B1/en not_active Expired - Lifetime
- 1994-04-04 US US08/244,548 patent/US5874556A/en not_active Expired - Fee Related
- 1994-04-04 DE DE69431715T patent/DE69431715T2/de not_active Expired - Fee Related
- 1994-04-04 WO PCT/US1994/003659 patent/WO1994022489A1/en active IP Right Grant
- 1994-04-04 AT AT94914020T patent/ATE227772T1/de not_active IP Right Cessation
- 1994-04-04 JP JP6522444A patent/JPH08510901A/ja not_active Ceased
- 1994-04-04 CA CA002159898A patent/CA2159898A1/en not_active Abandoned
-
1998
- 1998-12-16 US US09/213,993 patent/US6593124B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE69431715D1 (de) | 2002-12-19 |
US5874556A (en) | 1999-02-23 |
EP0693940A1 (en) | 1996-01-31 |
ES2186685T3 (es) | 2003-05-16 |
ATE227772T1 (de) | 2002-11-15 |
EP0693940B1 (en) | 2002-11-13 |
AU6624894A (en) | 1994-10-24 |
AU695615B2 (en) | 1998-08-20 |
DK0693940T3 (da) | 2002-12-16 |
EP0693940A4 (en) | 1998-08-19 |
WO1994022489A1 (en) | 1994-10-13 |
DE69431715T2 (de) | 2003-07-03 |
CA2159898A1 (en) | 1994-10-13 |
JPH08510901A (ja) | 1996-11-19 |
US6593124B1 (en) | 2003-07-15 |
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