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Application filed by Toyama Chemical Co LtdfiledCriticalToyama Chemical Co Ltd
Priority to PT6472076ApriorityCriticalpatent/PT64720B/en
Publication of PT64720ApublicationCriticalpatent/PT64720A/en
Publication of PT64720BpublicationCriticalpatent/PT64720B/en
Cephalosporins of formula (I): (where R1 = H, a cation or a blocking group and R2 = acetoxy (cpd. C) carbamyloxy (cpd. D), 5-methyl-1,3,4-thiazol-2-ylthio (cpd. B) or 1-methyl-1,2,3,4-tetrazol-5-ylthio (cpd. A)), are broad spectrum antibiotics effective against Gram-positive and Gram-negative bacteria (partic. Pseudomonas aeruginosa, Klebsiella pneumoniae and Proteus species) and stable to bacterial beta-lactamase. The cpds. have low toxicity, are well absorbed to give high blood levels and do not show hemolytic activity.
PT6472076A1976-01-201976-01-20
PROCESS FOR THE PREPARATION OF NEW CEFALOSPORINS
PT64720B
(en)