PT3719021T - Inibidores da cinase 1 associada a adaptador, composições compreendendo estes, e métodos da sua utilização - Google Patents
Inibidores da cinase 1 associada a adaptador, composições compreendendo estes, e métodos da sua utilizaçãoInfo
- Publication number
- PT3719021T PT3719021T PT201776044T PT20177604T PT3719021T PT 3719021 T PT3719021 T PT 3719021T PT 201776044 T PT201776044 T PT 201776044T PT 20177604 T PT20177604 T PT 20177604T PT 3719021 T PT3719021 T PT 3719021T
- Authority
- PT
- Portugal
- Prior art keywords
- inhibitors
- compositions
- methods
- associated kinase
- adapter associated
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461953976P | 2014-03-17 | 2014-03-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3719021T true PT3719021T (pt) | 2022-04-08 |
Family
ID=52727478
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT157120262T PT3119783T (pt) | 2014-03-17 | 2015-03-16 | Inibidores de quinase associada a adaptadores 1, composições que os compreendem e métodos para sua utilização |
| PT201776044T PT3719021T (pt) | 2014-03-17 | 2015-03-16 | Inibidores da cinase 1 associada a adaptador, composições compreendendo estes, e métodos da sua utilização |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT157120262T PT3119783T (pt) | 2014-03-17 | 2015-03-16 | Inibidores de quinase associada a adaptadores 1, composições que os compreendem e métodos para sua utilização |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US9682982B2 (hu) |
| EP (2) | EP3719021B1 (hu) |
| JP (1) | JP6553081B2 (hu) |
| CN (1) | CN106103447B (hu) |
| AR (1) | AR099766A1 (hu) |
| AU (1) | AU2015231672B2 (hu) |
| CA (1) | CA2941870C (hu) |
| DK (2) | DK3719021T3 (hu) |
| ES (2) | ES2911388T3 (hu) |
| HK (1) | HK1226065A1 (hu) |
| HU (1) | HUE050975T2 (hu) |
| PL (2) | PL3719021T3 (hu) |
| PT (2) | PT3119783T (hu) |
| TW (1) | TW201620911A (hu) |
| WO (1) | WO2015142714A1 (hu) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX345830B (es) * | 2012-03-09 | 2017-02-17 | Lexicon Pharmaceuticals Inc | Compuestos a base de pirazol[1,5-a]pirimidina, composiciones que los comprenden, y metodos para su uso. |
| CN105979950A (zh) | 2013-10-11 | 2016-09-28 | 百时美施贵宝公司 | 吡咯并三嗪激酶抑制剂 |
| CN109369576B (zh) * | 2018-09-19 | 2020-11-27 | 上海凌凯医药科技有限公司 | 一种合成3-甲基氧杂环丁烷-3-(4-硝基苯基)碳酸酯的方法 |
| CN115484951A (zh) | 2020-04-21 | 2022-12-16 | 莱西肯医药有限公司 | 用于治疗病毒感染的aak1抑制剂 |
| JP2023522689A (ja) * | 2020-04-21 | 2023-05-31 | レクシコン ファーマシューティカルズ インコーポレイテッド | ＣｏＶ－２２９Ｅ又はＣｏＶ－ＯＣ４３コロナウイルス感染症の治療において使用される４－（３－（ピリジン－３－イル）ピラゾロ［１，５－ａ］ピリミジン－５－イル）ピペラジン |
| WO2023196584A2 (en) * | 2022-04-08 | 2023-10-12 | New York University | Endocytosis inhibitors and their use for pain treatment |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5464764A (en) | 1989-08-22 | 1995-11-07 | University Of Utah Research Foundation | Positive-negative selection methods and vectors |
| AU2515992A (en) | 1991-08-20 | 1993-03-16 | Genpharm International, Inc. | Gene targeting in animal cells using isogenic dna constructs |
| US6194410B1 (en) * | 1998-03-11 | 2001-02-27 | Hoffman-La Roche Inc. | Pyrazolopyrimidine and pyrazolines and process for preparation thereof |
| EP1873157A1 (en) * | 2006-06-21 | 2008-01-02 | Bayer Schering Pharma Aktiengesellschaft | Pyrazolopyrimidines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same |
| US8591943B2 (en) * | 2009-04-09 | 2013-11-26 | Merck Sharp & Dohme Corp. | Pyrazolo[1,5-a]pyrimidine derivatives as mTOR inhibitors |
| UA110324C2 (en) * | 2009-07-02 | 2015-12-25 | Genentech Inc | Jak inhibitory compounds based on pyrazolo pyrimidine |
| WO2011030139A1 (en) * | 2009-09-11 | 2011-03-17 | Astrazeneca Ab | 4- (pyrimidin-2-yl) -piperazine and 4- (pyrimidin-2-yl) -piperidine derivatives as gpr119 modulators |
| WO2011087999A1 (en) * | 2010-01-14 | 2011-07-21 | Merck Sharp & Dohme Corp. | Pyrazolo[1,5-a]pyrimidines as mark inhibitors |
| WO2012034095A1 (en) * | 2010-09-09 | 2012-03-15 | Irm Llc | Compounds and compositions as trk inhibitors |
| MX345830B (es) * | 2012-03-09 | 2017-02-17 | Lexicon Pharmaceuticals Inc | Compuestos a base de pirazol[1,5-a]pirimidina, composiciones que los comprenden, y metodos para su uso. |
| US20140080834A1 (en) * | 2012-03-09 | 2014-03-20 | Thomas Herbert Lanthorn | Inhibition of adaptor associated kinase 1 for the treatment of pain |
| MX347917B (es) * | 2012-03-09 | 2017-05-17 | Lexicon Pharmaceuticals Inc | Compuestos a base de imidazo[1,2-b]piridazina, composiciones que los comprenden, y metodos para su uso. |
-
2015
- 2015-03-04 TW TW104106872A patent/TW201620911A/zh unknown
- 2015-03-16 CN CN201580014255.6A patent/CN106103447B/zh active Active
- 2015-03-16 AU AU2015231672A patent/AU2015231672B2/en active Active
- 2015-03-16 AR ARP150100787A patent/AR099766A1/es unknown
- 2015-03-16 CA CA2941870A patent/CA2941870C/en active Active
- 2015-03-16 US US14/658,653 patent/US9682982B2/en active Active
- 2015-03-16 ES ES20177604T patent/ES2911388T3/es active Active
- 2015-03-16 PL PL20177604T patent/PL3719021T3/pl unknown
- 2015-03-16 JP JP2016557251A patent/JP6553081B2/ja active Active
- 2015-03-16 EP EP20177604.4A patent/EP3719021B1/en active Active
- 2015-03-16 HU HUE15712026A patent/HUE050975T2/hu unknown
- 2015-03-16 DK DK20177604.4T patent/DK3719021T3/da active
- 2015-03-16 PL PL15712026T patent/PL3119783T3/pl unknown
- 2015-03-16 EP EP15712026.2A patent/EP3119783B1/en active Active
- 2015-03-16 WO PCT/US2015/020696 patent/WO2015142714A1/en active Application Filing
- 2015-03-16 DK DK15712026.2T patent/DK3119783T3/da active
- 2015-03-16 PT PT157120262T patent/PT3119783T/pt unknown
- 2015-03-16 ES ES15712026T patent/ES2821441T3/es active Active
- 2015-03-16 PT PT201776044T patent/PT3719021T/pt unknown
-
2016
- 2016-12-16 HK HK16114377A patent/HK1226065A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN106103447B (zh) | 2019-07-16 |
| US20160039824A1 (en) | 2016-02-11 |
| PL3719021T3 (pl) | 2022-06-20 |
| HUE050975T2 (hu) | 2021-01-28 |
| ES2821441T3 (es) | 2021-04-26 |
| EP3119783A1 (en) | 2017-01-25 |
| EP3719021B1 (en) | 2022-03-09 |
| AU2015231672B2 (en) | 2019-06-20 |
| CN106103447A (zh) | 2016-11-09 |
| CA2941870A1 (en) | 2015-09-24 |
| TW201620911A (zh) | 2016-06-16 |
| JP2017507980A (ja) | 2017-03-23 |
| WO2015142714A1 (en) | 2015-09-24 |
| JP6553081B2 (ja) | 2019-07-31 |
| PL3119783T3 (pl) | 2021-01-11 |
| AU2015231672A1 (en) | 2016-09-15 |
| CA2941870C (en) | 2022-07-19 |
| AR099766A1 (es) | 2016-08-17 |
| EP3719021A1 (en) | 2020-10-07 |
| DK3119783T3 (da) | 2020-09-28 |
| PT3119783T (pt) | 2020-09-24 |
| EP3119783B1 (en) | 2020-06-24 |
| DK3719021T3 (da) | 2022-06-13 |
| ES2911388T3 (es) | 2022-05-19 |
| HK1226065A1 (zh) | 2017-09-22 |
| US9682982B2 (en) | 2017-06-20 |
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