PT3694526T - Resgate independente do genótipo da fibrose quística com canais de bicarbonato de moléculas pequenas - Google Patents
Resgate independente do genótipo da fibrose quística com canais de bicarbonato de moléculas pequenasInfo
- Publication number
- PT3694526T PT3694526T PT188654834T PT18865483T PT3694526T PT 3694526 T PT3694526 T PT 3694526T PT 188654834 T PT188654834 T PT 188654834T PT 18865483 T PT18865483 T PT 18865483T PT 3694526 T PT3694526 T PT 3694526T
- Authority
- PT
- Portugal
- Prior art keywords
- agnostic
- genotype
- rescue
- bicarbonate
- channels
- Prior art date
Links
- 201000003883 Cystic fibrosis Diseases 0.000 title 1
- -1 small molecule bicarbonate Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Dispersion Chemistry (AREA)
- Otolaryngology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762570795P | 2017-10-11 | 2017-10-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3694526T true PT3694526T (pt) | 2025-01-20 |
Family
ID=66100102
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT188654834T PT3694526T (pt) | 2017-10-11 | 2018-10-11 | Resgate independente do genótipo da fibrose quística com canais de bicarbonato de moléculas pequenas |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US12090164B2 (enExample) |
| EP (1) | EP3694526B1 (enExample) |
| JP (2) | JP7355335B2 (enExample) |
| AU (2) | AU2018348214C1 (enExample) |
| CA (1) | CA3076246A1 (enExample) |
| DK (1) | DK3694526T3 (enExample) |
| ES (1) | ES3009563T3 (enExample) |
| FI (1) | FI3694526T3 (enExample) |
| PT (1) | PT3694526T (enExample) |
| WO (1) | WO2019075214A2 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7355335B2 (ja) | 2017-10-11 | 2023-10-03 | ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティ オブ イリノイ | 小分子重炭酸イオンチャネルを用いた嚢胞性線維症の遺伝子型非依存性救済 |
| KR20240164801A (ko) | 2022-03-21 | 2024-11-20 | 더 보오드 오브 트러스티스 오브 더 유니버시티 오브 일리노이즈 | 암포테리신 b의 지질-코팅된 결정을 포함하는 이온 채널 보형 조성물 |
| WO2025019806A2 (en) * | 2023-07-19 | 2025-01-23 | The Board Of Trustees Of The University Of Illinois | Restoring physiology with small molecule mimics of missing proteins |
| WO2025064626A1 (en) * | 2023-09-20 | 2025-03-27 | The Board Of Trustees Of The University Of Illinois | Additive effects for molecular prosthetcs and cftr modulators in cf epithelia |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU598958B2 (en) * | 1987-11-12 | 1990-07-05 | Vestar, Inc. | Improved amphotericin b liposome preparation |
| AU643141B2 (en) | 1991-03-15 | 1993-11-04 | Amgen, Inc. | Pulmonary administration of granulocyte colony stimulating factor |
| US5451569A (en) | 1994-04-19 | 1995-09-19 | Hong Kong University Of Science And Technology R & D Corporation Limited | Pulmonary drug delivery system |
| JP5118302B2 (ja) * | 2002-10-29 | 2013-01-16 | トランセイブ, インク. | 抗感染剤の徐放 |
| TWI249408B (en) | 2003-12-10 | 2006-02-21 | Ind Tech Res Inst | New antifungal formulation and manufacturing method thereof |
| ATE476965T1 (de) * | 2004-06-11 | 2010-08-15 | Verma Jitendra Nath | Sterol-angereicherte multilamellare amphotericin- enthaltende liposomen in kochsalzlösung und herstellungsverfahren |
| WO2011050311A1 (en) | 2009-10-22 | 2011-04-28 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Use of endostatin peptides for the treatment of fibrosis |
| US8945605B2 (en) * | 2011-06-07 | 2015-02-03 | Parion Sciences, Inc. | Aerosol delivery systems, compositions and methods |
| US20180015115A1 (en) * | 2014-11-04 | 2018-01-18 | The Board Of Trustees Of The University Of Illinois | Restoring physiology with small molecule mimics of missing proteins |
| DK3439668T3 (da) * | 2016-04-08 | 2024-09-02 | Univ Illinois | Småmolekylemedieret genoprettelse af luftvejsoverfladefysiologi i lungeepiteler ved human cystisk fibrose |
| WO2017181193A2 (en) * | 2016-04-15 | 2017-10-19 | The Uab Research Foundation | Methods and compounds for stimulating read-through of premature termination codons |
| JP7355335B2 (ja) | 2017-10-11 | 2023-10-03 | ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティ オブ イリノイ | 小分子重炭酸イオンチャネルを用いた嚢胞性線維症の遺伝子型非依存性救済 |
-
2018
- 2018-10-11 JP JP2020517886A patent/JP7355335B2/ja active Active
- 2018-10-11 US US16/754,651 patent/US12090164B2/en active Active
- 2018-10-11 PT PT188654834T patent/PT3694526T/pt unknown
- 2018-10-11 AU AU2018348214A patent/AU2018348214C1/en active Active
- 2018-10-11 CA CA3076246A patent/CA3076246A1/en active Pending
- 2018-10-11 EP EP18865483.4A patent/EP3694526B1/en active Active
- 2018-10-11 WO PCT/US2018/055435 patent/WO2019075214A2/en not_active Ceased
- 2018-10-11 FI FIEP18865483.4T patent/FI3694526T3/fi active
- 2018-10-11 ES ES18865483T patent/ES3009563T3/es active Active
- 2018-10-11 DK DK18865483.4T patent/DK3694526T3/da active
-
2023
- 2023-07-06 JP JP2023111218A patent/JP2023126932A/ja active Pending
-
2024
- 2024-09-16 US US18/886,316 patent/US20250000886A1/en active Pending
- 2024-09-16 US US18/886,318 patent/US20250009775A1/en active Pending
- 2024-11-06 AU AU2024259758A patent/AU2024259758A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2019075214A2 (en) | 2019-04-18 |
| JP2020536859A (ja) | 2020-12-17 |
| US20200352970A1 (en) | 2020-11-12 |
| DK3694526T3 (da) | 2025-02-03 |
| CA3076246A1 (en) | 2019-04-18 |
| EP3694526A2 (en) | 2020-08-19 |
| WO2019075214A3 (en) | 2020-04-02 |
| ES3009563T3 (en) | 2025-03-27 |
| AU2018348214B2 (en) | 2024-08-08 |
| US20250009775A1 (en) | 2025-01-09 |
| JP7355335B2 (ja) | 2023-10-03 |
| AU2024259758A1 (en) | 2024-11-21 |
| JP2023126932A (ja) | 2023-09-12 |
| FI3694526T3 (fi) | 2025-02-06 |
| AU2018348214A1 (en) | 2020-04-23 |
| US20250000886A1 (en) | 2025-01-02 |
| EP3694526B1 (en) | 2024-12-04 |
| EP3694526A4 (en) | 2021-06-09 |
| US12090164B2 (en) | 2024-09-17 |
| AU2018348214C1 (en) | 2025-01-30 |
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