PT3694526T - Resgate independente do genótipo da fibrose quística com canais de bicarbonato de moléculas pequenas - Google Patents

Resgate independente do genótipo da fibrose quística com canais de bicarbonato de moléculas pequenas

Info

Publication number
PT3694526T
PT3694526T PT188654834T PT18865483T PT3694526T PT 3694526 T PT3694526 T PT 3694526T PT 188654834 T PT188654834 T PT 188654834T PT 18865483 T PT18865483 T PT 18865483T PT 3694526 T PT3694526 T PT 3694526T
Authority
PT
Portugal
Prior art keywords
agnostic
genotype
rescue
bicarbonate
channels
Prior art date
Application number
PT188654834T
Other languages
English (en)
Portuguese (pt)
Original Assignee
Univ Illinois
Univ Iowa Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Illinois, Univ Iowa Res Found filed Critical Univ Illinois
Publication of PT3694526T publication Critical patent/PT3694526T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT188654834T 2017-10-11 2018-10-11 Resgate independente do genótipo da fibrose quística com canais de bicarbonato de moléculas pequenas PT3694526T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762570795P 2017-10-11 2017-10-11

Publications (1)

Publication Number Publication Date
PT3694526T true PT3694526T (pt) 2025-01-20

Family

ID=66100102

Family Applications (1)

Application Number Title Priority Date Filing Date
PT188654834T PT3694526T (pt) 2017-10-11 2018-10-11 Resgate independente do genótipo da fibrose quística com canais de bicarbonato de moléculas pequenas

Country Status (10)

Country Link
US (3) US12090164B2 (enExample)
EP (1) EP3694526B1 (enExample)
JP (2) JP7355335B2 (enExample)
AU (2) AU2018348214C1 (enExample)
CA (1) CA3076246A1 (enExample)
DK (1) DK3694526T3 (enExample)
ES (1) ES3009563T3 (enExample)
FI (1) FI3694526T3 (enExample)
PT (1) PT3694526T (enExample)
WO (1) WO2019075214A2 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7355335B2 (ja) 2017-10-11 2023-10-03 ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティ オブ イリノイ 小分子重炭酸イオンチャネルを用いた嚢胞性線維症の遺伝子型非依存性救済
KR20240164801A (ko) 2022-03-21 2024-11-20 더 보오드 오브 트러스티스 오브 더 유니버시티 오브 일리노이즈 암포테리신 b의 지질-코팅된 결정을 포함하는 이온 채널 보형 조성물
WO2025019806A2 (en) * 2023-07-19 2025-01-23 The Board Of Trustees Of The University Of Illinois Restoring physiology with small molecule mimics of missing proteins
WO2025064626A1 (en) * 2023-09-20 2025-03-27 The Board Of Trustees Of The University Of Illinois Additive effects for molecular prosthetcs and cftr modulators in cf epithelia

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU598958B2 (en) * 1987-11-12 1990-07-05 Vestar, Inc. Improved amphotericin b liposome preparation
AU643141B2 (en) 1991-03-15 1993-11-04 Amgen, Inc. Pulmonary administration of granulocyte colony stimulating factor
US5451569A (en) 1994-04-19 1995-09-19 Hong Kong University Of Science And Technology R & D Corporation Limited Pulmonary drug delivery system
JP5118302B2 (ja) * 2002-10-29 2013-01-16 トランセイブ, インク. 抗感染剤の徐放
TWI249408B (en) 2003-12-10 2006-02-21 Ind Tech Res Inst New antifungal formulation and manufacturing method thereof
ATE476965T1 (de) * 2004-06-11 2010-08-15 Verma Jitendra Nath Sterol-angereicherte multilamellare amphotericin- enthaltende liposomen in kochsalzlösung und herstellungsverfahren
WO2011050311A1 (en) 2009-10-22 2011-04-28 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Use of endostatin peptides for the treatment of fibrosis
US8945605B2 (en) * 2011-06-07 2015-02-03 Parion Sciences, Inc. Aerosol delivery systems, compositions and methods
US20180015115A1 (en) * 2014-11-04 2018-01-18 The Board Of Trustees Of The University Of Illinois Restoring physiology with small molecule mimics of missing proteins
DK3439668T3 (da) * 2016-04-08 2024-09-02 Univ Illinois Småmolekylemedieret genoprettelse af luftvejsoverfladefysiologi i lungeepiteler ved human cystisk fibrose
WO2017181193A2 (en) * 2016-04-15 2017-10-19 The Uab Research Foundation Methods and compounds for stimulating read-through of premature termination codons
JP7355335B2 (ja) 2017-10-11 2023-10-03 ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティ オブ イリノイ 小分子重炭酸イオンチャネルを用いた嚢胞性線維症の遺伝子型非依存性救済

Also Published As

Publication number Publication date
WO2019075214A2 (en) 2019-04-18
JP2020536859A (ja) 2020-12-17
US20200352970A1 (en) 2020-11-12
DK3694526T3 (da) 2025-02-03
CA3076246A1 (en) 2019-04-18
EP3694526A2 (en) 2020-08-19
WO2019075214A3 (en) 2020-04-02
ES3009563T3 (en) 2025-03-27
AU2018348214B2 (en) 2024-08-08
US20250009775A1 (en) 2025-01-09
JP7355335B2 (ja) 2023-10-03
AU2024259758A1 (en) 2024-11-21
JP2023126932A (ja) 2023-09-12
FI3694526T3 (fi) 2025-02-06
AU2018348214A1 (en) 2020-04-23
US20250000886A1 (en) 2025-01-02
EP3694526B1 (en) 2024-12-04
EP3694526A4 (en) 2021-06-09
US12090164B2 (en) 2024-09-17
AU2018348214C1 (en) 2025-01-30

Similar Documents

Publication Publication Date Title
IL272032A (en) Methods of treatment for cystic fibrosis
ZA201703054B (en) Modulators of cystic fibrosis transmembrane conductance regulator
PL3436446T3 (pl) Modulatory mukowiscydozowego przezbłonowego regulatora przewodnictwa
EP3012003A4 (en) Combined toy gyroscope capable of being freely assembled
EP3009174A4 (en) Combined toy gyroscope capable of splitting automatically
ZA201901252B (en) Activity-triggered provisioning of portable wireless networks
IL252818A0 (en) Cyclopropanecarboxamides that modulate cystic fibrosis transmembrane conductance regulation
EP3012004A4 (en) Toy gyroscope with gyroscope ring capable of being mounted on both sides
PT3694526T (pt) Resgate independente do genótipo da fibrose quística com canais de bicarbonato de moléculas pequenas
EP3536343A4 (en) SKIN FIBROSIS TREATMENT AGENT
IL262141B (en) A method for diagnosing cystic fibrosis
CA3291070A1 (en) Portable foam brush
EP3392424A4 (en) LIGHTWEIGHT WALL BODY FRAME
EP3596067C0 (en) NEW PYRAZOLE DERIVATIVES FOR THE TREATMENT OF CYSTIC FIBROSIS
EP3508630A4 (en) SHELL FABRIC WITH MOTION TRACKING
EP3240461A4 (en) Personal applicator
GB201721718D0 (en) Treatment of cystic fibrosis
ZA201807388B (en) Pesticidally active mixtures of tioxazafen
HK40089592A (en) Modulators of cystic fibrosis transmembrane conductance regulator
TWM533984U (en) Detachable massage roller structure
EP3326662A4 (en) USE OF POROUS MATERIAL
TWM533983U (en) Massager structure
AU201816640S (en) Hedgehog toy
HK1245655A1 (en) Cyclopropanecarboxamide modulators of cystic fibrosis transmembrane conductance regulator
GB201700824D0 (en) Sustained propulsion