PT3658194T - Radiomarcador e agente terapêutico de modo duplo - Google Patents

Radiomarcador e agente terapêutico de modo duplo

Info

Publication number
PT3658194T
PT3658194T PT187435409T PT18743540T PT3658194T PT 3658194 T PT3658194 T PT 3658194T PT 187435409 T PT187435409 T PT 187435409T PT 18743540 T PT18743540 T PT 18743540T PT 3658194 T PT3658194 T PT 3658194T
Authority
PT
Portugal
Prior art keywords
radiotracer
therapeutics
dual mode
dual
mode
Prior art date
Application number
PT187435409T
Other languages
English (en)
Portuguese (pt)
Original Assignee
Technische Univ Muenchen Klinikum Rechts Der Isar
Univ Muenchen Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Technische Univ Muenchen Klinikum Rechts Der Isar, Univ Muenchen Tech filed Critical Technische Univ Muenchen Klinikum Rechts Der Isar
Publication of PT3658194T publication Critical patent/PT3658194T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0402Organic compounds carboxylic acid carriers, fatty acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0474Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0497Organic compounds conjugates with a carrier being an organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Nuclear Medicine (AREA)
PT187435409T 2017-07-28 2018-07-30 Radiomarcador e agente terapêutico de modo duplo PT3658194T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP17183795 2017-07-28

Publications (1)

Publication Number Publication Date
PT3658194T true PT3658194T (pt) 2025-02-13

Family

ID=59501286

Family Applications (1)

Application Number Title Priority Date Filing Date
PT187435409T PT3658194T (pt) 2017-07-28 2018-07-30 Radiomarcador e agente terapêutico de modo duplo

Country Status (20)

Country Link
US (3) US11413360B2 (enExample)
EP (3) EP3658194B1 (enExample)
JP (2) JP7059372B2 (enExample)
KR (2) KR102752620B1 (enExample)
CN (1) CN111132700B (enExample)
AU (2) AU2018308699B2 (enExample)
BR (1) BR112020001785A2 (enExample)
CA (1) CA3071315A1 (enExample)
DK (1) DK3658194T3 (enExample)
EA (1) EA202090370A1 (enExample)
ES (1) ES3011272T3 (enExample)
FI (1) FI3658194T3 (enExample)
HU (1) HUE070098T2 (enExample)
IL (2) IL318092A (enExample)
MX (2) MX2020000352A (enExample)
PL (1) PL3658194T3 (enExample)
PT (1) PT3658194T (enExample)
SG (1) SG11202000725WA (enExample)
WO (1) WO2019020831A1 (enExample)
ZA (1) ZA202000467B (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11413360B2 (en) * 2017-07-28 2022-08-16 Technische Universität München Dual mode radiotracer and—therapeutics
AU2020213678B2 (en) 2019-01-30 2024-05-30 Technische Universität München PSMA binding dual mode radiotracer and therapeutic
WO2020157128A1 (en) * 2019-01-30 2020-08-06 Technische Universität München Silicon-fluoride acceptor substituted radiopharmaceuticals and precursors thereof
IL303420A (en) * 2019-01-30 2023-08-01 Univ Muenchen Tech Diagnostic imaging materials for cancer
CN112168978B (zh) * 2019-07-03 2022-01-11 北京大学 一种抗体偶联药物及其药物组合物与应用
CA3155519A1 (en) * 2019-10-29 2021-05-06 Steve Shih-Lin Huang Psma-targeting imaging agents
CN113350531A (zh) * 2020-03-02 2021-09-07 上海核力星医药科技有限公司 前列腺特异性膜抗原结合配体偶联物及其应用
GB202005282D0 (en) * 2020-04-09 2020-05-27 Blue Earth Diagnostics Ltd Pharmaceutical Formulations
EP4185336A1 (en) 2020-07-23 2023-05-31 Technische Universität München Silicon-containing ligand compounds
WO2022051684A1 (en) 2020-09-03 2022-03-10 Curium Us Llc Radiolabeling and formulation for scale up of 64cu-dotatate
EP4023250A1 (en) 2021-01-04 2022-07-06 Technische Universität München Dual mode radiotracer and -therapeutics
JP2024507343A (ja) * 2021-02-15 2024-02-19 テクニシェ ユニバーシタット ミュンヘン デュアルモード放射性トレーサーおよびその療法
IL308414A (en) * 2021-05-14 2024-01-01 Technische Universit?T M?Nchen Radiopharmaceutical somatostatin receptor ligands and their precursors
GB202108779D0 (en) 2021-06-18 2021-08-04 Blue Earth Diagnostics Ltd Si-at therapeutic/diagnostic compounds
GB202109922D0 (en) 2021-07-09 2021-08-25 Blue Earth Diagnostics Ltd Radiotracers and therapeutics binding to fibroblast activation protein (fap)
WO2023012282A1 (en) * 2021-08-05 2023-02-09 Technische Universität München Ligand compounds comprising a chelating group as a bridging group
GB202113646D0 (en) 2021-09-24 2021-11-10 Blue Earth Diagnostics Ltd Method of preparation of 18F labelled silyl-fluoride compounds
CN114671806B (zh) * 2022-04-08 2024-03-01 上海如絮生物科技有限公司 一种亲水性吡啶衍生物、中间体、其制备方法及应用
GB202207372D0 (en) 2022-05-19 2022-07-06 Blue Earth Diagnostics Ltd Synthesis of fluorosilyl compounds
CA3257852A1 (en) 2022-07-29 2024-02-01 Technische Universitat Munchen Silicon Fluoride Accepting Groups for Radiopharmaceutical Products
WO2024054226A1 (en) * 2022-09-06 2024-03-14 Hoang Ba Xuan Gallium nitrate and dimethyl sulfoxide composition for respiratory treatment
JP2025532619A (ja) * 2022-09-20 2025-10-01 テクニシェ ユニバーシタット ミュンヘン イメージングおよび標的化放射線治療のための新規ミニガストリン由来コレシストキニン2受容体結合分子
TW202426433A (zh) 2022-09-23 2024-07-01 瑞士商紐利迪姆股份公司 成纖維細胞活化蛋白(fap)抑制劑、fap結合物及其診斷與治療用途
JP2025539087A (ja) * 2022-11-14 2025-12-03 アクティス オンコロジー, インコーポレイテッド 腎臓におけるミニタンパク質の減少された保持
WO2025072791A2 (en) 2023-09-29 2025-04-03 Aktis Oncology, Inc. Miniproteins, conjugates & uses thereof
GB202316239D0 (en) 2023-10-24 2023-12-06 Blue Earth Diagnostics Ltd Therapeutic combination

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995001346A1 (en) * 1993-06-30 1995-01-12 Akzo Nobel N.V. Chelating compounds
CA2455598A1 (en) 2001-07-27 2003-02-13 Targesome, Inc. Lipid constructs as therapeutic and imaging agents
CN102626522B (zh) * 2012-04-12 2014-09-10 韩彦江 基于趋化因子受体cxcr4多肽类拮抗剂的多肽放射性诊断与治疗药物
AU2015273934B2 (en) * 2014-06-10 2020-08-20 3B Pharmaceuticals Gmbh Conjugate comprising a neurotensin receptor ligand and use thereof
WO2016062370A1 (en) 2014-10-20 2016-04-28 Deutsches Krebsforschungszentrum 18f-tagged inhibitors of prostate specific membrane antigen (psma), their use as imaging agents and pharmaceutical agents for the treatment of prostate cancer
US20160287730A1 (en) * 2015-03-31 2016-10-06 The United States Of America, As Represented By The Secretary, Department Of Health And Human Serv Labeled evans blue dye derivative for in vivo serum albumin labeling
US10800797B2 (en) * 2015-05-26 2020-10-13 California Institute Of Technology Heteroaromatic silicon-fluoride-acceptors useful for 18F labeling of molecules and biomolecules, and methods of preparing same
US11413360B2 (en) 2017-07-28 2022-08-16 Technische Universität München Dual mode radiotracer and—therapeutics
WO2019115547A1 (en) * 2017-12-11 2019-06-20 Technische Universität München Psma ligands for imaging and endoradiotherapy
IL303420A (en) 2019-01-30 2023-08-01 Univ Muenchen Tech Diagnostic imaging materials for cancer
AU2020213678B2 (en) 2019-01-30 2024-05-30 Technische Universität München PSMA binding dual mode radiotracer and therapeutic

Also Published As

Publication number Publication date
US12453787B2 (en) 2025-10-28
ES3011272T3 (en) 2025-04-07
FI3658194T3 (fi) 2025-02-28
JP7059372B2 (ja) 2022-04-25
WO2019020831A1 (en) 2019-01-31
MX2020000352A (es) 2020-08-17
AU2018308699A1 (en) 2020-01-23
AU2018308699B2 (en) 2023-11-30
IL272291B2 (en) 2025-06-01
IL272291B1 (en) 2025-02-01
JP2022101601A (ja) 2022-07-06
CN111132700B (zh) 2022-12-13
KR20240027896A (ko) 2024-03-04
DK3658194T3 (da) 2025-02-17
BR112020001785A2 (pt) 2020-09-29
HUE070098T2 (hu) 2025-05-28
PL3658194T3 (pl) 2025-09-15
AU2024200440A1 (en) 2024-02-08
EP3658194A1 (en) 2020-06-03
EP4424378A3 (en) 2024-12-11
US20220370649A1 (en) 2022-11-24
SG11202000725WA (en) 2020-02-27
KR20200064057A (ko) 2020-06-05
ZA202000467B (en) 2022-06-29
US20250121102A1 (en) 2025-04-17
US12390540B2 (en) 2025-08-19
JP2020528461A (ja) 2020-09-24
EA202090370A1 (ru) 2020-05-25
KR102752620B1 (ko) 2025-01-10
IL272291A (en) 2020-03-31
MX2023007914A (es) 2023-07-13
CN111132700A (zh) 2020-05-08
IL318092A (en) 2025-02-01
AU2024200440B2 (en) 2025-04-24
US20200197545A1 (en) 2020-06-25
US11413360B2 (en) 2022-08-16
EP3658194B1 (en) 2024-11-27
CA3071315A1 (en) 2019-01-31
EP4000640A1 (en) 2022-05-25
EP4424378A2 (en) 2024-09-04

Similar Documents

Publication Publication Date Title
ZA202000467B (en) Dual mode radiotracer and -therapeutics
SG10202108418TA (en) Multi-hypotheses merge mode
GB201708456D0 (en) Senolytic compounds
GB201700814D0 (en) Compounds
GB201704327D0 (en) Compounds
GB201715342D0 (en) Compounds
ZA201906811B (en) Phenyl-2-hydroxy-acetylamino-2-methyl-phenyl compounds
GB201704325D0 (en) Compounds
GB201716871D0 (en) Compounds
GB201713962D0 (en) Compounds
GB201707938D0 (en) Compounds
GB201707856D0 (en) Compounds
GB201706162D0 (en) Compounds
GB201702221D0 (en) Compounds
GB201716369D0 (en) Compounds
GB201715786D0 (en) Compounds
GB201716392D0 (en) Compounds
GB201707852D0 (en) Compounds
GB201815211D0 (en) Not known
GB201717050D0 (en) Compounds
GB201716688D0 (en) Compounds
GB201716352D0 (en) Compounds
GB201716374D0 (en) Compounds
GB201713318D0 (en) Compounds
GB201713319D0 (en) Compounds