PT3621609T - Sanfetrinem ou um sal ou um éster do mesmo para a sua utilização no tratamento de infeções micobacterianas - Google Patents
Sanfetrinem ou um sal ou um éster do mesmo para a sua utilização no tratamento de infeções micobacterianasInfo
- Publication number
- PT3621609T PT3621609T PT187210539T PT18721053T PT3621609T PT 3621609 T PT3621609 T PT 3621609T PT 187210539 T PT187210539 T PT 187210539T PT 18721053 T PT18721053 T PT 18721053T PT 3621609 T PT3621609 T PT 3621609T
- Authority
- PT
- Portugal
- Prior art keywords
- sanfetrinem
- ester
- salt
- mycobacterial infection
- treating mycobacterial
- Prior art date
Links
- ICFDDEJRXZSWTA-KJFVXYAMSA-N (1s,5s,8as,8br)-1-[(1r)-1-hydroxyethyl]-5-methoxy-2-oxo-5,6,7,8,8a,8b-hexahydro-1h-azeto[1,2-b]isoindole-4-carboxylic acid Chemical compound OC(=O)C1=C2[C@@H](OC)CCC[C@@H]2[C@H]2N1C(=O)[C@@H]2[C@@H](C)O ICFDDEJRXZSWTA-KJFVXYAMSA-N 0.000 title 1
- 206010062207 Mycobacterial infection Diseases 0.000 title 1
- 150000002148 esters Chemical class 0.000 title 1
- 208000027531 mycobacterial infectious disease Diseases 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- 229950010458 sanfetrinem Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/12—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals attached in position 7
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/133—Amines having hydroxy groups, e.g. sphingosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/08—Antibacterial agents for leprosy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17382255 | 2017-05-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3621609T true PT3621609T (pt) | 2022-08-24 |
Family
ID=58709903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT187210539T PT3621609T (pt) | 2017-05-08 | 2018-05-04 | Sanfetrinem ou um sal ou um éster do mesmo para a sua utilização no tratamento de infeções micobacterianas |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US11253500B2 (pt) |
| EP (1) | EP3621609B1 (pt) |
| JP (1) | JP7123074B2 (pt) |
| KR (1) | KR102575872B1 (pt) |
| CN (1) | CN110869016B (pt) |
| AU (1) | AU2018265192B2 (pt) |
| BR (1) | BR112019023322B1 (pt) |
| CA (1) | CA3060396A1 (pt) |
| DK (1) | DK3621609T3 (pt) |
| ES (1) | ES2925215T3 (pt) |
| HR (1) | HRP20221212T1 (pt) |
| HU (1) | HUE059818T2 (pt) |
| LT (1) | LT3621609T (pt) |
| PL (1) | PL3621609T3 (pt) |
| PT (1) | PT3621609T (pt) |
| RS (1) | RS63461B1 (pt) |
| RU (1) | RU2757272C2 (pt) |
| SI (1) | SI3621609T1 (pt) |
| WO (1) | WO2018206466A1 (pt) |
| ZA (1) | ZA201906810B (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111184718A (zh) * | 2018-11-15 | 2020-05-22 | 鲁南制药集团股份有限公司 | 法罗培南在制备治疗初治病原学阳性肺结核药物中的用途 |
| CN117462551B (zh) * | 2023-12-27 | 2024-05-17 | 深圳国家感染性疾病临床医学研究中心 | 茚地那韦和/或其衍生物在制备抗结核药物中的应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ285778B6 (cs) | 1989-09-08 | 1999-11-17 | Glaxo S.P.A. | Kyselina 10-(1-hydroxyethyl)-11-oxo-1-azatricyklo/7,2,0,03,8/-undec-2en-2-karboxylová a její deriváty, způsob jejich výroby, použití pro výrobu farmaceutických prostředků a farmaceutické prostředky s jejich obsahem |
| GB9018330D0 (en) | 1990-08-21 | 1990-10-03 | Glaxo Spa | Heterocyclic compounds |
| IL99248A (en) | 1990-08-21 | 1996-01-31 | Glaxo Spa | Acid esters 01-) 1-Hydroxyethyl (-11-oxo-1-azatricycloundec-2-n-2-carboxylic acid, their preparation and pharmaceutical preparations |
| GB9104769D0 (en) | 1991-03-07 | 1991-04-17 | Glaxo Spa | Heterocyclic compounds |
| GB9305813D0 (en) | 1993-03-20 | 1993-05-05 | Glaxo Spa | Chemical process |
| EP2085084A1 (en) * | 2008-01-29 | 2009-08-05 | LEK Pharmaceuticals D.D. | Use of inhibitor of beta-lactamases and its combination with beta-lactam antibiotics |
| EP2135871A1 (en) * | 2008-06-18 | 2009-12-23 | LEK Pharmaceuticals D.D. | New trinem antibiotics and inhibitors of beta-lactamases |
| EP3209288A1 (en) * | 2014-09-25 | 2017-08-30 | Manu Chaudhary | Stealth, targeted nanoparticles (stn) for oral drug delivery |
| MA41494B1 (fr) * | 2015-02-12 | 2020-10-28 | Glaxosmithkline Ip No 2 Ltd | Composés benzoxaborole substitués en position 4 et utilisations associées |
-
2018
- 2018-05-04 CN CN201880030277.5A patent/CN110869016B/zh active Active
- 2018-05-04 HU HUE18721053A patent/HUE059818T2/hu unknown
- 2018-05-04 AU AU2018265192A patent/AU2018265192B2/en active Active
- 2018-05-04 ES ES18721053T patent/ES2925215T3/es active Active
- 2018-05-04 JP JP2019561315A patent/JP7123074B2/ja active Active
- 2018-05-04 US US16/611,908 patent/US11253500B2/en active Active
- 2018-05-04 WO PCT/EP2018/061615 patent/WO2018206466A1/en unknown
- 2018-05-04 BR BR112019023322-9A patent/BR112019023322B1/pt active IP Right Grant
- 2018-05-04 PL PL18721053.9T patent/PL3621609T3/pl unknown
- 2018-05-04 SI SI201830762T patent/SI3621609T1/sl unknown
- 2018-05-04 RU RU2019139864A patent/RU2757272C2/ru active
- 2018-05-04 DK DK18721053.9T patent/DK3621609T3/da active
- 2018-05-04 PT PT187210539T patent/PT3621609T/pt unknown
- 2018-05-04 EP EP18721053.9A patent/EP3621609B1/en active Active
- 2018-05-04 CA CA3060396A patent/CA3060396A1/en active Pending
- 2018-05-04 KR KR1020197032729A patent/KR102575872B1/ko active IP Right Grant
- 2018-05-04 LT LTEPPCT/EP2018/061615T patent/LT3621609T/lt unknown
- 2018-05-04 HR HRP20221212TT patent/HRP20221212T1/hr unknown
- 2018-05-04 RS RS20220731A patent/RS63461B1/sr unknown
-
2019
- 2019-10-16 ZA ZA2019/06810A patent/ZA201906810B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR112019023322A2 (pt) | 2020-06-16 |
| RU2757272C2 (ru) | 2021-10-12 |
| KR102575872B1 (ko) | 2023-09-08 |
| CA3060396A1 (en) | 2018-11-15 |
| RU2019139864A3 (pt) | 2021-06-28 |
| ES2925215T3 (es) | 2022-10-14 |
| CN110869016B (zh) | 2023-09-12 |
| EP3621609A1 (en) | 2020-03-18 |
| HRP20221212T1 (hr) | 2022-12-09 |
| EP3621609B1 (en) | 2022-07-27 |
| HUE059818T2 (hu) | 2022-12-28 |
| KR20200003816A (ko) | 2020-01-10 |
| RU2019139864A (ru) | 2021-06-09 |
| CN110869016A (zh) | 2020-03-06 |
| US20200289462A1 (en) | 2020-09-17 |
| SI3621609T1 (sl) | 2022-10-28 |
| JP2020519592A (ja) | 2020-07-02 |
| AU2018265192A1 (en) | 2019-11-07 |
| AU2018265192B2 (en) | 2021-06-17 |
| JP7123074B2 (ja) | 2022-08-22 |
| US11253500B2 (en) | 2022-02-22 |
| PL3621609T3 (pl) | 2022-11-14 |
| ZA201906810B (en) | 2021-03-31 |
| RS63461B1 (sr) | 2022-08-31 |
| DK3621609T3 (da) | 2022-08-29 |
| WO2018206466A1 (en) | 2018-11-15 |
| LT3621609T (lt) | 2022-10-10 |
| BR112019023322B1 (pt) | 2023-11-14 |
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