PT3529234T - Compostos, processo para a obtenção dos compostos, composição farmacêutica, uso dos compostos e método para tratamento de distúrbios psiquiátricos e/ou distúrbios do sono - Google Patents

Compostos, processo para a obtenção dos compostos, composição farmacêutica, uso dos compostos e método para tratamento de distúrbios psiquiátricos e/ou distúrbios do sono

Info

Publication number
PT3529234T
PT3529234T PT178651550T PT17865155T PT3529234T PT 3529234 T PT3529234 T PT 3529234T PT 178651550 T PT178651550 T PT 178651550T PT 17865155 T PT17865155 T PT 17865155T PT 3529234 T PT3529234 T PT 3529234T
Authority
PT
Portugal
Prior art keywords
compounds
obtaining
disorders
pharmaceutical composition
treating psychiatric
Prior art date
Application number
PT178651550T
Other languages
English (en)
Portuguese (pt)
Original Assignee
Ache Laboratorios Farmaceuticos Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ache Laboratorios Farmaceuticos Sa filed Critical Ache Laboratorios Farmaceuticos Sa
Publication of PT3529234T publication Critical patent/PT3529234T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • C07D491/044Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28Sulfur atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT178651550T 2016-10-24 2017-10-23 Compostos, processo para a obtenção dos compostos, composição farmacêutica, uso dos compostos e método para tratamento de distúrbios psiquiátricos e/ou distúrbios do sono PT3529234T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BR102016024814A BR102016024814A2 (pt) 2016-10-24 2016-10-24 composto, processo de obtenção do composto, composição farmacêutica, uso do composto e método de tratamento de desordens psiquiátricas e/ou distúrbios do sono

Publications (1)

Publication Number Publication Date
PT3529234T true PT3529234T (pt) 2024-02-01

Family

ID=62023150

Family Applications (1)

Application Number Title Priority Date Filing Date
PT178651550T PT3529234T (pt) 2016-10-24 2017-10-23 Compostos, processo para a obtenção dos compostos, composição farmacêutica, uso dos compostos e método para tratamento de distúrbios psiquiátricos e/ou distúrbios do sono

Country Status (20)

Country Link
US (2) US10781182B2 (https=)
EP (2) EP3529234B1 (https=)
JP (1) JP7194683B2 (https=)
KR (1) KR102594251B1 (https=)
CN (2) CN115181108A (https=)
AR (1) AR109467A1 (https=)
AU (1) AU2017351756B2 (https=)
BR (1) BR102016024814A2 (https=)
CL (1) CL2019001105A1 (https=)
CO (1) CO2019004756A2 (https=)
DK (1) DK3529234T3 (https=)
EC (1) ECSP19032963A (https=)
ES (2) ES2970546T3 (https=)
FI (1) FI3529234T3 (https=)
MX (1) MX392990B (https=)
PE (2) PE20250558A1 (https=)
PT (1) PT3529234T (https=)
SG (2) SG10202009001TA (https=)
UY (2) UY37334A (https=)
WO (1) WO2018076090A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR102016024814A2 (pt) * 2016-10-24 2018-05-08 Aché Laboratórios Farmacêuticos S.A. composto, processo de obtenção do composto, composição farmacêutica, uso do composto e método de tratamento de desordens psiquiátricas e/ou distúrbios do sono
EP3640251B1 (en) 2016-10-24 2021-12-08 Astrazeneca AB 6,7,8,9-tetrahydro-3h-pyrazolo[4,3-f]isoquinoline derivatives useful in the treatment of cancer
PL3494116T3 (pl) 2017-01-30 2020-04-30 Astrazeneca Ab Modulatory receptora estrogenowego
AR121842A1 (es) * 2020-04-15 2022-07-13 Ache Laboratorios Farmaceuticos Sa Compuesto de benzimidazol para el tratamiento de trastornos metabólicos
MX2022013391A (es) 2020-04-24 2022-11-30 Astrazeneca Ab Pauta posologica para el tratamiento del cancer.
MX2022013258A (es) 2020-04-24 2022-11-14 Astrazeneca Ab Formulaciones farmaceuticas.

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2658818B1 (fr) 1990-02-27 1993-12-31 Adir Cie Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US5260051A (en) 1990-12-17 1993-11-09 Lever Brothers Company, Division Of Conopco, Inc. Compositions comprising phosphate ester compounds containing a beneficial reagent component
FR2674524B1 (fr) 1991-03-25 1993-05-21 Adir Nouveaux amides alkyl heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2680366B1 (fr) * 1991-08-13 1995-01-20 Adir Nouveaux derives d'arylethylamines, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
GB9326192D0 (en) 1993-12-22 1994-02-23 Glaxo Group Ltd Chemical compounds
JP3559045B2 (ja) * 1994-06-10 2004-08-25 ナウチノ−イススレドバテルスキ インスティテュト ファルマコロギイ ロスシイスコイ アカデミイ メディツィンスキフ ナウク 薬理学的活性を有する2−メルカプトベンズイミダゾール誘導体
US5496826A (en) 1994-09-02 1996-03-05 Bristol-Myers Squibb Company Pharmaceutical methods of using heterocyclic derivatives of N-phenylamides
FR2738818B1 (fr) 1995-09-18 1997-12-05 Valentonine Nouveaux derives d'oxydation d'indolylalkylamines, et leur utilisation a titre de medicament
JP2884153B2 (ja) * 1996-03-08 1999-04-19 武田薬品工業株式会社 三環性化合物、その製造法および剤
US6034239A (en) * 1996-03-08 2000-03-07 Takeda Chemical Industries, Ltd. Tricyclic compounds, their production and use
RU2190609C2 (ru) 1996-12-10 2002-10-10 Бристол-Маерс Сквибб Компани Производные бензодиоксола, бензофурана, дигидробензофурана и бензодиоксана и содержащие их композиции
US6214869B1 (en) 1998-06-05 2001-04-10 Bristol-Myers Squibb Heterocyclic cis cyclopropane derivatives as melatonergic agents
DE60007745T2 (de) 1999-06-30 2005-03-10 Bristol-Myers Squibb Co. Heterocyclische aminopyrrolidon-derivate als melatonergene wirkstoffe
US7408067B2 (en) 2002-01-17 2008-08-05 Merck + Co., Inc. Aza-cyclic compounds as modulators of acetylcholine receptors
CN1922141A (zh) * 2004-02-23 2007-02-28 大日本住友制药株式会社 新的杂环化合物
ES2264641B1 (es) * 2005-06-17 2008-03-01 Quimica Sintetica, S.A. Procedimiento para la obtencion de derivados de bencimidazol y sus intermedios.
US20090298811A1 (en) * 2006-09-12 2009-12-03 Pfizer Inc Benzimidazolone derivatives
US20100056515A1 (en) * 2006-10-25 2010-03-04 Kazuyoshi Aso Benzimidazole compounds
RU2401831C2 (ru) * 2008-12-15 2010-10-20 Алла Хем, Ллс Средство, снижающее влечение к алкоголю, фармацевтическая композиция и способы ее получения, лекарственное средство и способ лечения
BR102016024814A2 (pt) * 2016-10-24 2018-05-08 Aché Laboratórios Farmacêuticos S.A. composto, processo de obtenção do composto, composição farmacêutica, uso do composto e método de tratamento de desordens psiquiátricas e/ou distúrbios do sono

Also Published As

Publication number Publication date
AR109467A1 (es) 2018-12-12
EP3741760C0 (en) 2024-12-04
DK3529234T3 (da) 2024-02-05
SG11201903113TA (en) 2019-05-30
EP3529234A4 (en) 2020-03-11
CN110088092B (zh) 2022-10-04
JP7194683B2 (ja) 2022-12-22
JP2019537624A (ja) 2019-12-26
US11091445B2 (en) 2021-08-17
CO2019004756A2 (es) 2019-05-21
BR112019008197A2 (pt) 2019-07-16
CN115181108A (zh) 2022-10-14
MX392990B (es) 2025-03-24
BR102016024814A2 (pt) 2018-05-08
PE20250558A1 (es) 2025-02-24
CL2019001105A1 (es) 2019-09-06
US10781182B2 (en) 2020-09-22
SG10202009001TA (en) 2020-10-29
CN110088092A (zh) 2019-08-02
ES3013994T3 (en) 2025-04-16
US20190270711A1 (en) 2019-09-05
EP3741760A1 (en) 2020-11-25
PE20191046A1 (es) 2019-08-06
US20200277265A1 (en) 2020-09-03
ES2970546T3 (es) 2024-05-29
UY40644A (es) 2024-02-29
CA3042040A1 (en) 2018-05-03
EP3529234B1 (en) 2023-11-29
MX2019004782A (es) 2019-10-09
FI3529234T3 (fi) 2023-12-28
AU2017351756B2 (en) 2022-01-27
AU2017351756A1 (en) 2019-05-09
KR20190066023A (ko) 2019-06-12
ECSP19032963A (es) 2019-05-31
EP3741760B1 (en) 2024-12-04
UY37334A (es) 2018-04-30
EP3529234A1 (en) 2019-08-28
WO2018076090A1 (en) 2018-05-03
KR102594251B1 (ko) 2023-10-25

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