PT3245233T - Processo de preparação de ésteres butíricos de sal de sódio do ácido hialurónico em meio aquoso - Google Patents

Processo de preparação de ésteres butíricos de sal de sódio do ácido hialurónico em meio aquoso

Info

Publication number
PT3245233T
PT3245233T PT16701095T PT16701095T PT3245233T PT 3245233 T PT3245233 T PT 3245233T PT 16701095 T PT16701095 T PT 16701095T PT 16701095 T PT16701095 T PT 16701095T PT 3245233 T PT3245233 T PT 3245233T
Authority
PT
Portugal
Prior art keywords
preparation
water
sodium salt
hyaluronic acid
acid sodium
Prior art date
Application number
PT16701095T
Other languages
English (en)
Inventor
Stucchi Luca
Gianni Rita
Sechi Alessandra
Original Assignee
Bmg Pharma S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bmg Pharma S P A filed Critical Bmg Pharma S P A
Publication of PT3245233T publication Critical patent/PT3245233T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/042—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/34—Materials or treatment for tissue regeneration for soft tissue reconstruction

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Birds (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Vascular Medicine (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
PT16701095T 2015-01-13 2016-01-08 Processo de preparação de ésteres butíricos de sal de sódio do ácido hialurónico em meio aquoso PT3245233T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI20150017 2015-01-13

Publications (1)

Publication Number Publication Date
PT3245233T true PT3245233T (pt) 2019-01-16

Family

ID=52574320

Family Applications (1)

Application Number Title Priority Date Filing Date
PT16701095T PT3245233T (pt) 2015-01-13 2016-01-08 Processo de preparação de ésteres butíricos de sal de sódio do ácido hialurónico em meio aquoso

Country Status (14)

Country Link
US (1) US10618982B2 (pt)
EP (1) EP3245233B1 (pt)
JP (1) JP6738337B2 (pt)
KR (1) KR102636528B1 (pt)
CN (1) CN107106694B (pt)
BR (1) BR112017014849B1 (pt)
CA (1) CA2973416C (pt)
DK (1) DK3245233T3 (pt)
ES (1) ES2704290T3 (pt)
PL (1) PL3245233T3 (pt)
PT (1) PT3245233T (pt)
RU (1) RU2708994C2 (pt)
WO (1) WO2016113192A1 (pt)
ZA (1) ZA201704637B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT201900021693A1 (it) * 2019-11-20 2021-05-20 Bmg Pharma S P A Derivati butirrati o butirrati e formiati dell’acido ialuronico reticolati e loro procedimento di reticolazione
IT202000001831A1 (it) * 2020-01-30 2021-07-30 Caprika Srl Composizione per applicazione rettale a base di sale di acido butirrico per il trattamento delle patologie proctologiche
CN116444695B (zh) * 2022-12-27 2024-09-06 山东丰金美业科技有限公司 一种低成本、低分子量乙酰化透明质酸钠的制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0639582B1 (en) 1985-03-15 1998-09-16 Antivirals Inc. Polynucleotide assay reagent and method
EP0416250A3 (en) * 1989-08-01 1991-08-28 The Research Foundation Of State University Of New York N-acylurea and o-acylisourea derivatives of hyaluronic acid
US5616568A (en) * 1993-11-30 1997-04-01 The Research Foundation Of State University Of New York Functionalized derivatives of hyaluronic acid
JP3563440B2 (ja) * 1994-05-16 2004-09-08 生化学工業株式会社 アシル化ヒアルロン酸の製造法
IT1286510B1 (it) * 1996-11-29 1998-07-15 Cooperativa Centro Ricerche Po Esteri butirrici ad attivita' antiproliferativa e composizioni farmaceutiche che li contengono
ITMI20022745A1 (it) * 2002-12-23 2004-06-24 Coimex Scrl United Companies Esteri misti dell'acido ialuronico ad attivita' citostatica e prodifferenziante e procedimento per la loro produzione.
ITMI20030043A1 (it) 2003-01-14 2004-07-15 Coimex S C R L United Companies Uso di esteri retinoici dell'acido ialuronico in cellule
US7091191B2 (en) * 2003-12-19 2006-08-15 Ethicon, Inc. Modified hyaluronic acid for use in musculoskeletal tissue repair
ITMI20040605A1 (it) * 2004-03-29 2004-06-29 Coimex S C R L United Companie Esteri butirrici dell'acido ialuronico a basso grado di sostituzione procedimento per la loro preparazione ed uso
FR2908415B1 (fr) * 2006-11-10 2009-01-23 Abr Dev Sarl Acide hyaluronique reticule et son procede de preparation
EP1942117A1 (en) * 2006-12-29 2008-07-09 Sigea S.R.L. Derivatives of acid polysaccharides
ITMI20072237A1 (it) * 2007-11-27 2009-05-28 Sigea Srl Esteri misti butirrico-formico di polisaccaridi acidi, loro preparazione ed uso come dermocosmetici
US20090143348A1 (en) * 2007-11-30 2009-06-04 Ahmet Tezel Polysaccharide gel compositions and methods for sustained delivery of drugs
WO2012048283A1 (en) * 2010-10-08 2012-04-12 Board Of Regents, The University Of Texas System One-step processing of hydrogels for mechanically robust and chemically desired features
ITGE20120102A1 (it) 2012-10-25 2014-04-26 Lipogems Internat S R L Procedimento di precondizionamento chimico di materiale cellulare per ottenere la riprogrammazione epigenetica chimica e l'espressione di pluripotenzialità

Also Published As

Publication number Publication date
CN107106694A (zh) 2017-08-29
WO2016113192A1 (en) 2016-07-21
CA2973416C (en) 2023-05-09
RU2708994C2 (ru) 2019-12-12
CA2973416A1 (en) 2016-07-21
BR112017014849B1 (pt) 2022-05-17
EP3245233A1 (en) 2017-11-22
RU2017124364A3 (pt) 2019-07-17
US10618982B2 (en) 2020-04-14
RU2017124364A (ru) 2019-02-14
DK3245233T3 (en) 2019-01-28
ZA201704637B (en) 2018-12-19
KR20170105010A (ko) 2017-09-18
KR102636528B1 (ko) 2024-02-15
BR112017014849A2 (pt) 2018-01-09
JP2018501385A (ja) 2018-01-18
PL3245233T3 (pl) 2019-06-28
US20180273648A1 (en) 2018-09-27
EP3245233B1 (en) 2018-10-24
ES2704290T3 (es) 2019-03-15
JP6738337B2 (ja) 2020-08-12
CN107106694B (zh) 2020-09-22

Similar Documents

Publication Publication Date Title
HUE050414T2 (hu) Eljárás hialuronsav nátriumsója elõállítására és tisztítására
HK1245762A1 (zh) 丙烯酸生產方法
ZA201706944B (en) Process for the purification of water
HUE055703T2 (hu) Eljárás hialuronsav tisztítására
ZA201700254B (en) Process for the preparation of 4-alkoxy-3-hydroxypicolinic acids
HK1250717A1 (zh) 製備乙酰半乳糖胺酸衍生物的方法
SG11201706506YA (en) Acetic acid process
IL243456A0 (en) A process for the preparation of fondaprinox sodium
HK1258219A1 (zh) 生產n-視黃醯基半胱磺酸烷基酯的方法
PL3328523T3 (pl) Sposób odzyskiwania siarczanu sodu
ZA201704637B (en) Process in water for the preparation of butyric esters of hyaluronic acid sodium salt
PL3271322T3 (pl) Proces oczyszczania kwasu monochloroacetycznego
ZA201801991B (en) Process for the preparation of monochloroacetic acid
PL3125867T3 (pl) Hiperosmolarna kompozycja kwasu hialuronowego
EP3936499C0 (en) PROCESS FOR PREPARING ACETIC ACID
PT3302409T (pt) Processo e composição para estimular a síntese do ácido hialurónico
IL243454A0 (en) A process for the preparation of fondaprinox sodium
PL3183228T3 (pl) Sposób oczyszczania kwasu akrylowego
HUP1500446A2 (en) Simple industrial process for the preparation of isodehydroacetic acid ester
EP3227260A4 (en) Process for the preparation of levulinic acid
EP3148977A4 (en) Process for the preparation of 4-dimethylaminocrotonic acid
EP3364959A4 (en) COMPOSITION FOR THE TREATMENT OF BARRENESS IN FEMALE SUBJECTS
RS63644B1 (sr) Postupak za proizvodnju sirćetne kiseline recikliranjem vode
SG11201702610XA (en) Method for producing aqueous acrylic acid polymer solution