PT3142701T - Novo tratamento - Google Patents

Novo tratamento

Info

Publication number
PT3142701T
PT3142701T PT15724354T PT15724354T PT3142701T PT 3142701 T PT3142701 T PT 3142701T PT 15724354 T PT15724354 T PT 15724354T PT 15724354 T PT15724354 T PT 15724354T PT 3142701 T PT3142701 T PT 3142701T
Authority
PT
Portugal
Prior art keywords
new treatment
treatment
new
Prior art date
Application number
PT15724354T
Other languages
English (en)
Inventor
Abbott-Banner Katharine
Hanrahan John
Thomas David
Original Assignee
Verona Pharma Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1408384.4A external-priority patent/GB201408384D0/en
Priority claimed from GBGB1417719.0A external-priority patent/GB201417719D0/en
Application filed by Verona Pharma Plc filed Critical Verona Pharma Plc
Publication of PT3142701T publication Critical patent/PT3142701T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/443Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/05Immunological preparations stimulating the reticulo-endothelial system, e.g. against cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/12Mucolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT15724354T 2014-05-12 2015-05-11 Novo tratamento PT3142701T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1408384.4A GB201408384D0 (en) 2014-05-12 2014-05-12 New treatment
GBGB1417719.0A GB201417719D0 (en) 2014-10-07 2014-10-07 New treatment

Publications (1)

Publication Number Publication Date
PT3142701T true PT3142701T (pt) 2018-10-18

Family

ID=53264683

Family Applications (2)

Application Number Title Priority Date Filing Date
PT15724354T PT3142701T (pt) 2014-05-12 2015-05-11 Novo tratamento
PT171744469T PT3231444T (pt) 2014-05-12 2015-05-11 Novo tratamento

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT171744469T PT3231444T (pt) 2014-05-12 2015-05-11 Novo tratamento

Country Status (16)

Country Link
US (2) US10864213B2 (pt)
EP (2) EP3142701B1 (pt)
AU (1) AU2015261239B2 (pt)
CA (1) CA2948620C (pt)
CY (2) CY1120550T1 (pt)
DK (2) DK3142701T3 (pt)
ES (2) ES2773142T3 (pt)
HU (1) HUE048020T2 (pt)
IL (1) IL248856B (pt)
MX (1) MX2016014756A (pt)
PL (2) PL3142701T3 (pt)
PT (2) PT3142701T (pt)
RU (1) RU2688191C2 (pt)
SI (2) SI3142701T1 (pt)
WO (1) WO2015173551A1 (pt)
ZA (1) ZA201607705B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3219705T3 (pl) 2005-12-28 2020-08-10 Vertex Pharmaceuticals Incorporated Kompozycje farmaceutyczne amorficznych postaci n-[2,4-bis(1,1-dimetyloetylo)-5-hydroksyfenylo]-1,4-dihydro-4-oksochinolino-3-karboksyamidu
US8563573B2 (en) 2007-11-02 2013-10-22 Vertex Pharmaceuticals Incorporated Azaindole derivatives as CFTR modulators
US8802868B2 (en) 2010-03-25 2014-08-12 Vertex Pharmaceuticals Incorporated Solid forms of (R)-1(2,2-difluorobenzo[D][1,3]dioxo1-5-yl)-N-(1-(2,3-dihydroxypropyl-6-fluoro-2-(1-hydroxy-2-methylpropan2-yl)-1H-Indol-5-yl)-Cyclopropanecarboxamide
CN105130948A (zh) 2010-04-22 2015-12-09 弗特克斯药品有限公司 制备环烷基甲酰胺基-吲哚化合物的方法
RS57476B9 (sr) 2014-04-15 2021-10-29 Vertex Pharma Farmaceutske kompozicije za lečenje bolesti posredovanih transmembranskim regulatorom provodljivosti cistične fibroze
WO2015173551A1 (en) 2014-05-12 2015-11-19 Verona Pharma Plc New treatment
NZ729796A (en) 2014-09-15 2024-01-26 Verona Pharma Plc Liquid inhalation formulation comprising rpl554
GB201502260D0 (en) 2015-02-11 2015-04-01 Verona Pharma Plc Salt of Pyrimido[6,1-A]Isoquinolin-4-one compound
GB201613054D0 (en) 2016-07-28 2016-09-14 Verona Pharma Plc New compound and process
IT201700085714A1 (it) * 2017-07-26 2019-01-26 Luigi Maiuri Approccio terapeutico per il trattamento e/o prevenzione di condizioni di sensibilità al glutine.
GB2578093B (en) * 2018-10-09 2020-11-18 Verona Pharma Plc Liquid pharmaceutical composition comprising RPL554 and HFA-134A
GB201911517D0 (en) * 2019-08-12 2019-09-25 Verona Pharma Plc Pharmaceutical composition
CA3160752A1 (en) * 2019-12-26 2021-07-01 Preston E. BRATCHER Methods of treating cystic fibrosis transmembrane conductance regulator (cftr) dysfunction

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE455946B (sv) 1986-10-20 1988-08-22 Trion Forskning & Utveckling Nya pertussistoxin-polypeptider och antigener samt testsatser, vacciner och intradermala hudtestkompositioner
US5874063A (en) 1991-04-11 1999-02-23 Astra Aktiebolag Pharmaceutical formulation
WO1992022286A1 (en) 1991-06-12 1992-12-23 Minnesota Mining And Manufacturing Company Albuterol sulfate suspension aerosol formulations
WO1993011747A1 (en) 1991-12-18 1993-06-24 Minnesota Mining And Manufacturing Company Suspension aerosol formulations
US5983956A (en) 1994-10-03 1999-11-16 Astra Aktiebolag Formulation for inhalation
SE9501384D0 (sv) 1995-04-13 1995-04-13 Astra Ab Process for the preparation of respirable particles
US6040344A (en) 1996-11-11 2000-03-21 Sepracor Inc. Formoterol process
NZ507619A (en) 1998-04-18 2003-05-30 Glaxo Group Ltd Pharmaceutical aerosol formulation with liquefied propellant gas
GB9808802D0 (en) 1998-04-24 1998-06-24 Glaxo Group Ltd Pharmaceutical formulations
SE9804000D0 (sv) 1998-11-23 1998-11-23 Astra Ab New composition of matter
DE60005493T2 (de) 1999-03-31 2004-07-01 Vernalis Ltd., Wokingham Pyrimido[6,1-a]isochinolinonderivate
US7090831B1 (en) 1999-04-14 2006-08-15 Smithkline Beecham Corporation Pharmaceutical aerosol formulation
RS53895B1 (en) 2004-06-24 2015-08-31 Vertex Pharmaceuticals Incorporated ATP-BINDING CASSETTE TRANSPORT MODULATORS
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
CN108117546A (zh) 2008-11-06 2018-06-05 弗特克斯药品有限公司 Atp-结合盒转运蛋白调节剂
CN105175479B (zh) 2009-09-11 2017-06-09 奇斯药制品公司 异噁唑烷衍生物
EP2603509B1 (en) * 2010-08-09 2014-06-18 Verona Pharma PLC Crystalline form of pyrimido[6,1-a] isoquinolin-4-one compound
BR112013012160A2 (pt) 2010-11-26 2019-09-24 Chiesi Farm Spa compostos, composição farmacêutica, uso de um composto e dispositivo
WO2012107364A1 (en) * 2011-02-07 2012-08-16 Scipharm Sàrl Novel composition for the treatment of cystic fibrosis
EP2744493A1 (en) * 2011-08-18 2014-06-25 Shire AG Combinations of a 5-ht4 receptor agonist and a pde4 inhibitor for use in therapy
EP2819670A1 (en) * 2012-02-27 2015-01-07 Vertex Pharmaceuticals Incorporated Pharmaceutical composition and administration thereof
CN105229547A (zh) 2013-03-14 2016-01-06 林肯环球股份有限公司 导出或者使用针对外部系统的焊接定序器数据的系统和方法
HUE037275T2 (hu) 2013-03-15 2018-08-28 Verona Pharma Plc Gyógyszer-kombináció
WO2015173551A1 (en) 2014-05-12 2015-11-19 Verona Pharma Plc New treatment
NZ729796A (en) 2014-09-15 2024-01-26 Verona Pharma Plc Liquid inhalation formulation comprising rpl554
GB201502260D0 (en) 2015-02-11 2015-04-01 Verona Pharma Plc Salt of Pyrimido[6,1-A]Isoquinolin-4-one compound
GB201613054D0 (en) 2016-07-28 2016-09-14 Verona Pharma Plc New compound and process
GB2578093B (en) 2018-10-09 2020-11-18 Verona Pharma Plc Liquid pharmaceutical composition comprising RPL554 and HFA-134A
GB202002786D0 (en) 2020-02-27 2020-04-15 Verona Pharma Plc Liquid pharmaceutical composition

Also Published As

Publication number Publication date
SI3231444T1 (sl) 2020-04-30
RU2016148447A3 (pt) 2018-12-27
SI3142701T1 (en) 2018-08-31
CY1120550T1 (el) 2019-07-10
DK3142701T3 (en) 2018-08-13
EP3231444A1 (en) 2017-10-18
ES2773142T3 (es) 2020-07-09
US10864213B2 (en) 2020-12-15
CA2948620C (en) 2023-01-24
ZA201607705B (en) 2020-05-27
PL3231444T3 (pl) 2020-05-18
IL248856A0 (en) 2017-01-31
CY1122748T1 (el) 2021-03-12
PL3142701T3 (pl) 2018-11-30
HUE048020T2 (hu) 2020-05-28
EP3142701A1 (en) 2017-03-22
IL248856B (en) 2020-07-30
DK3231444T3 (da) 2020-03-16
US20210106585A1 (en) 2021-04-15
RU2688191C2 (ru) 2019-05-21
PT3231444T (pt) 2020-03-05
AU2015261239B2 (en) 2020-02-27
EP3231444B1 (en) 2019-12-18
WO2015173551A1 (en) 2015-11-19
RU2016148447A (ru) 2018-06-19
US20170112839A1 (en) 2017-04-27
MX2016014756A (es) 2017-03-23
US11759467B2 (en) 2023-09-19
AU2015261239A1 (en) 2016-12-01
CA2948620A1 (en) 2015-11-19
ES2682105T3 (es) 2018-09-18
EP3142701B1 (en) 2018-06-27

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