PT3041926T - Dispositivo para a modelação in vitro de tecidos in vivo de órgãos - Google Patents

Dispositivo para a modelação in vitro de tecidos in vivo de órgãos

Info

Publication number
PT3041926T
PT3041926T PT147589774T PT14758977T PT3041926T PT 3041926 T PT3041926 T PT 3041926T PT 147589774 T PT147589774 T PT 147589774T PT 14758977 T PT14758977 T PT 14758977T PT 3041926 T PT3041926 T PT 3041926T
Authority
PT
Portugal
Prior art keywords
organs
vivo tissues
vitro modelling
modelling
vitro
Prior art date
Application number
PT147589774T
Other languages
English (en)
Original Assignee
Univ Bern
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Bern filed Critical Univ Bern
Publication of PT3041926T publication Critical patent/PT3041926T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02Membranes; Filters
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02Membranes; Filters
    • C12M25/04Membranes; Filters in combination with well or multiwell plates, i.e. culture inserts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10Perfusion
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/04Mechanical means, e.g. sonic waves, stretching forces, pressure or shear stimuli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/08Chemical, biochemical or biological means, e.g. plasma jet, co-culture
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/40Means for regulation, monitoring, measurement or control, e.g. flow regulation of pressure
PT147589774T 2013-09-05 2014-09-05 Dispositivo para a modelação in vitro de tecidos in vivo de órgãos PT3041926T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP13183063 2013-09-05

Publications (1)

Publication Number Publication Date
PT3041926T true PT3041926T (pt) 2020-06-17

Family

ID=49117711

Family Applications (1)

Application Number Title Priority Date Filing Date
PT147589774T PT3041926T (pt) 2013-09-05 2014-09-05 Dispositivo para a modelação in vitro de tecidos in vivo de órgãos

Country Status (8)

Country Link
US (3) US10066198B2 (pt)
EP (2) EP3041926B1 (pt)
CN (2) CN105593358B (pt)
DK (1) DK3041926T3 (pt)
ES (1) ES2795974T3 (pt)
PL (1) PL3041926T3 (pt)
PT (1) PT3041926T (pt)
WO (1) WO2015032889A1 (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9790465B2 (en) 2013-04-30 2017-10-17 Corning Incorporated Spheroid cell culture well article and methods thereof
EP3132019A1 (en) 2014-04-16 2017-02-22 The Charles Stark Draper Laboratory, Inc. Microfluidic tissue model
US10564148B2 (en) * 2014-09-24 2020-02-18 Triad National Security, Llc Multi-organ media compositions and methods of their use
CN113481097A (zh) 2014-10-29 2021-10-08 康宁股份有限公司 灌注生物反应器平台
WO2016161090A1 (en) * 2015-04-01 2016-10-06 President And Fellows Of Harvard College Respiration device for analysis of a response to shear stress and foreign agents on cells
NL2014840B1 (en) * 2015-05-21 2017-01-31 Intecrypt B V Microfluidic device for in vitro 3D cell culture experimentation.
JP6480285B2 (ja) * 2015-08-04 2019-03-06 豊田合成株式会社 細胞培養器具およびその製造方法
US11130133B2 (en) 2015-08-12 2021-09-28 Meon Medical Solutions Gmbh & Co. Kg Device and method for determining the migration ability of amoeboidally mobile cells
ES2615512B1 (es) * 2015-11-06 2018-03-15 Universidad De Zaragoza Dispositivo y sistema microfluídico para el estudio de cultivos celulares
EP3231860A1 (en) * 2016-04-14 2017-10-18 Technische Universität Wien Microfluidic device
US11629319B2 (en) 2016-06-15 2023-04-18 Mimetas, B.V. Cell culture device and methods
US11001796B2 (en) 2016-11-23 2021-05-11 The Charles Stark Draper Laboratory, Inc. Bi-layer multi-well cell culture platform
AU2017364195B2 (en) * 2016-11-24 2023-02-02 AlveoliX Technologies AG Cell culturing system and method
CN106929403A (zh) * 2017-04-14 2017-07-07 西安医学院 一种用于药物高通量筛选的血脑屏障模拟装置
US11767499B2 (en) 2017-07-14 2023-09-26 Corning Incorporated Cell culture vessel
JP7245222B2 (ja) 2017-07-14 2023-03-23 コーニング インコーポレイテッド 手動又は自動で培地を交換するための3d細胞培養容器
US11857970B2 (en) 2017-07-14 2024-01-02 Corning Incorporated Cell culture vessel
EP3652292A1 (en) 2017-07-14 2020-05-20 Corning Incorporated Cell culture vessel for 3d culture and methods of culturing 3d cells
LU100595B1 (en) * 2017-12-27 2019-06-28 Luxembourg Inst Science & Tech List Cell bio-incubator with a variable internal pressure
CN108660076A (zh) * 2018-05-21 2018-10-16 中国科学院苏州生物医学工程技术研究所 一种仿真肺芯片模型
WO2020013847A1 (en) 2018-07-13 2020-01-16 Corning Incorporated Microcavity dishes with sidewall including liquid medium delivery surface
PL3649229T3 (pl) 2018-07-13 2021-12-06 Corning Incorporated Naczynia do hodowli komórkowych ze stabilizującymi urządzeniami
WO2020013851A1 (en) 2018-07-13 2020-01-16 Corning Incorporated Fluidic devices including microplates with interconnected wells
NL2022085B1 (en) 2018-11-28 2020-06-25 Mimetas B V Device for assessing mechanical strain induced in or by cells
US11007524B2 (en) * 2019-01-18 2021-05-18 National Tsing Hua University Automatic microfluidic system for rapid personalized drug screening and testing method for personalized antibiotic susceptibility
CN112080425A (zh) * 2020-09-07 2020-12-15 中国科学院上海微系统与信息技术研究所 一种器官芯片、上皮/内皮屏障模型器件及其制作方法
CN112635022B (zh) * 2020-11-27 2023-07-25 易波 用于吸持生物组织的亲水界面的评价方法及系统
CN112890822B (zh) * 2021-01-21 2022-02-08 北京理工大学 一种胎儿心电仿体
CN113528338A (zh) * 2021-07-19 2021-10-22 中国医科大学 一种用于药物筛选的专用组合模具及其使用方法
US20230113710A1 (en) * 2021-10-08 2023-04-13 Shanghai Ruiyu Biotech Co., Ltd. Culture devices
CN115820415A (zh) * 2022-07-21 2023-03-21 北京大橡科技有限公司 培养单元、培养组件、芯片以及类器官共培养模型及其构建方法和构建装置以及应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4789601A (en) * 1987-05-04 1988-12-06 Banes Albert J Biocompatible polyorganosiloxane composition for cell culture apparatus
US5470743A (en) * 1991-03-06 1995-11-28 Becton, Dickinson And Company Transmembrane cell culture device
US6472200B1 (en) * 1999-07-23 2002-10-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Device and method for performing a biological modification of a fluid
DE60013585T2 (de) * 2000-07-19 2005-09-15 Technodop Ltd. (Société de Droit Irlandais) Kulturraum und Bioreaktor zur ausserkörperlichen Tierzellenkultur
WO2004033616A1 (de) * 2002-09-16 2004-04-22 Pan-Biotech Gmbh Einrichtung zur kultivierung von zellen, insbesondere menschlicher oder tierischer zellen
WO2004081741A2 (en) 2003-03-10 2004-09-23 The Regents Of The University Of Michigan Integrated microfluidic control employing programmable tactile actuators
US20060270023A1 (en) * 2003-04-18 2006-11-30 Carnege Mellon University Three-dimentioal, flexible cell growth substrate and related methods
CA2700946A1 (en) 2007-09-28 2009-04-02 University Of Toronto A system, apparatus and method for applying mechanical force to a material
DK2313487T3 (en) * 2008-07-16 2018-06-18 Childrens Medical Center ORGANIZING DEVICE WITH MICRO-CHANNELS AND METHODS OF APPLICATION
WO2011014674A2 (en) * 2009-07-29 2011-02-03 Cornell University Microfluidic device for pharmacokinetic-pharmacodynamic study of drugs and uses thereof
TW201111501A (en) * 2009-09-29 2011-04-01 Univ Chang Gung High throughput cell culture system capable of providing mechanical force pressing stimulation
EP2639293B1 (en) * 2010-11-12 2021-10-20 Kanto Kagaku Kabushiki Kaisha Cell culture chamber, method for producing same, tissue model using cell culture chamber, and method for producing same
KR102117921B1 (ko) * 2011-02-28 2020-06-03 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 세포 배양 시스템
US20130143230A1 (en) * 2011-12-02 2013-06-06 The Trustees Of The Stevens Institute Of Technology Microfluidic-based cell-culturing platform and method
JP6189787B2 (ja) * 2014-04-28 2017-08-30 豊田合成株式会社 細胞培養器具

Also Published As

Publication number Publication date
CN105593358B (zh) 2021-12-21
US10066198B2 (en) 2018-09-04
US11473045B2 (en) 2022-10-18
US20230015127A1 (en) 2023-01-19
EP3041926B1 (en) 2020-03-04
CN105593358A (zh) 2016-05-18
CN114134042A (zh) 2022-03-04
DK3041926T3 (da) 2020-06-08
WO2015032889A1 (en) 2015-03-12
US20180355299A1 (en) 2018-12-13
US20160194588A1 (en) 2016-07-07
EP3041926A1 (en) 2016-07-13
EP3663388A1 (en) 2020-06-10
ES2795974T3 (es) 2020-11-25
PL3041926T3 (pl) 2020-11-02

Similar Documents

Publication Publication Date Title
PT3041926T (pt) Dispositivo para a modelação in vitro de tecidos in vivo de órgãos
IL243599A0 (en) surgical implant
PL2772206T3 (pl) Miękki ogranicznik narzędzia chirurgicznego
HK1221238A1 (zh) 疏水性組織粘著劑
PL2945549T3 (pl) Narzędzie chirurgiczne z napędem silnikowym
IL240398A0 (en) surgical implant
IL240349B (en) surgical implant
GB201300165D0 (en) Surgical instrument
EP2995263A4 (en) ENDOSCOPIC TREATMENT INSTRUMENT
IL240534A0 (en) surgical implant
EP3038549A4 (en) FABRIC INCISION DEVICE
EP3071127C0 (en) FEATURES FOR COUPLING COMPONENTS OF ULTRASOUND SURGICAL INSTRUMENTS
EP2943245A4 (en) MEDICAL INSTRUMENTS DIRECTED ACCURATELY
EP2979608A4 (en) ENDOSCOPY SURGERY DEVICE
GB201305171D0 (en) Measurement of tissue structures
EP2967876A4 (en) REMOVABLE REINFORCEMENT FOR A MEDICAL IMPLANT
EP2995262A4 (en) ENDOSCOPIC TREATMENT INSTRUMENT
PL3073936T3 (pl) Wszczep medyczny
EP2979615A4 (en) DEVICE FOR ENDOSCOPIC SURGERY
IL245647A0 (en) surgical gauze
EP2979619A4 (en) DEVICE FOR ENDOSCOPIC SURGERY
PL2815695T3 (pl) Instrument chirurgiczny z rozpoznawaniem tkanki
EP3081140A4 (en) Endoscope treatment instrument
PL2988659T3 (pl) Ulepszone sposoby charakterystyki tkanki
HK1213209A1 (zh) 用於醫療裝置的主體部分和隔膜材料