PT3016671T - Péptidos ativamente transportados e resistentes à protease como transportes bbb e construtos de transporte de carga - Google Patents

Péptidos ativamente transportados e resistentes à protease como transportes bbb e construtos de transporte de carga

Info

Publication number
PT3016671T
PT3016671T PT147387856T PT14738785T PT3016671T PT 3016671 T PT3016671 T PT 3016671T PT 147387856 T PT147387856 T PT 147387856T PT 14738785 T PT14738785 T PT 14738785T PT 3016671 T PT3016671 T PT 3016671T
Authority
PT
Portugal
Prior art keywords
shuttle
protease
actively transported
resistant peptides
shuttles
Prior art date
Application number
PT147387856T
Other languages
English (en)
Original Assignee
Univ Barcelona
Fundacio Inst De Recerca Biomedica Irb Barcelona
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Barcelona, Fundacio Inst De Recerca Biomedica Irb Barcelona filed Critical Univ Barcelona
Publication of PT3016671T publication Critical patent/PT3016671T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0063Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0069Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
    • A61K49/0089Particulate, powder, adsorbate, bead, sphere
    • A61K49/0091Microparticle, microcapsule, microbubble, microsphere, microbead, i.e. having a size or diameter higher or equal to 1 micrometer
    • A61K49/0093Nanoparticle, nanocapsule, nanobubble, nanosphere, nanobead, i.e. having a size or diameter smaller than 1 micrometer, e.g. polymeric nanoparticle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Nanotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT147387856T 2013-07-04 2014-07-03 Péptidos ativamente transportados e resistentes à protease como transportes bbb e construtos de transporte de carga PT3016671T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP13382274 2013-07-04

Publications (1)

Publication Number Publication Date
PT3016671T true PT3016671T (pt) 2021-12-02

Family

ID=48900923

Family Applications (1)

Application Number Title Priority Date Filing Date
PT147387856T PT3016671T (pt) 2013-07-04 2014-07-03 Péptidos ativamente transportados e resistentes à protease como transportes bbb e construtos de transporte de carga

Country Status (4)

Country Link
EP (1) EP3016671B1 (pt)
ES (1) ES2900592T3 (pt)
PT (1) PT3016671T (pt)
WO (1) WO2015001015A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2020114744A (ru) * 2017-10-02 2021-11-09 Седарс-Синаи Медикал Сентер Способы и композиции для эффективной доставки через множество биобарьеров
WO2020193441A1 (en) 2019-03-22 2020-10-01 Université de Paris New inhibitors of lrrk2/pp1 interaction
CN116406301A (zh) 2020-09-28 2023-07-07 生物医药研究基金会机构(Irb巴塞罗那) 可用于治疗癌症的sn38肽缀合物
WO2023186822A1 (en) 2022-03-28 2023-10-05 Hospital Sant Joan De Deu Peptidic water-soluble delivery system of anticancer drugs
WO2024028282A1 (en) 2022-08-01 2024-02-08 Gate2Brain, S.L. Site-specific modification by a bbb-shuttle of antibody-based entities for crossing the blood-brain barrier

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000069900A2 (en) * 1999-05-17 2000-11-23 Conjuchem, Inc. Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components
US7825093B2 (en) * 2006-10-25 2010-11-02 Amgen Inc. Methods of using OSK1 peptide analogs
WO2011154887A1 (fr) * 2010-06-07 2011-12-15 Assistance Publique - Hopitaux De Paris Méllitine pour son utilisation dans le traitement de la maladie de parkinson

Also Published As

Publication number Publication date
EP3016671B1 (en) 2021-09-08
WO2015001015A1 (en) 2015-01-08
EP3016671A1 (en) 2016-05-11
ES2900592T3 (es) 2022-03-17

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