PT2604695T - Vetores de arenavírus defeituosos para a replicação - Google Patents
Vetores de arenavírus defeituosos para a replicaçãoInfo
- Publication number
- PT2604695T PT2604695T PT131527277T PT13152727T PT2604695T PT 2604695 T PT2604695 T PT 2604695T PT 131527277 T PT131527277 T PT 131527277T PT 13152727 T PT13152727 T PT 13152727T PT 2604695 T PT2604695 T PT 2604695T
- Authority
- PT
- Portugal
- Prior art keywords
- replication
- arenavirus vectors
- defective arenavirus
- defective
- vectors
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- A61K2039/5256—Virus expressing foreign proteins
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2760/00011—Details
- C12N2760/10011—Arenaviridae
- C12N2760/10032—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2760/00011—Details
- C12N2760/10011—Arenaviridae
- C12N2760/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N2760/00011—Details
- C12N2760/10011—Arenaviridae
- C12N2760/10041—Use of virus, viral particle or viral elements as a vector
- C12N2760/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2760/00011—Details
- C12N2760/10011—Arenaviridae
- C12N2760/10061—Methods of inactivation or attenuation
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
- C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
- C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES
- C12N2840/206—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES having multiple IRES
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Diabetes (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Biophysics (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07025099 | 2007-12-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT2604695T true PT2604695T (pt) | 2022-12-07 |
Family
ID=40428182
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT131527277T PT2604695T (pt) | 2007-12-27 | 2008-12-22 | Vetores de arenavírus defeituosos para a replicação |
Country Status (16)
Country | Link |
---|---|
US (6) | US8592205B2 (pt) |
EP (3) | EP2238255B1 (pt) |
JP (3) | JP5642556B2 (pt) |
CN (3) | CN103255169A (pt) |
CA (1) | CA2744910C (pt) |
DK (2) | DK2604695T3 (pt) |
ES (2) | ES2937147T3 (pt) |
FI (1) | FI2604695T3 (pt) |
HK (1) | HK1151829A1 (pt) |
HR (1) | HRP20221475T3 (pt) |
HU (1) | HUE061060T2 (pt) |
LT (1) | LT2604695T (pt) |
PL (2) | PL2238255T3 (pt) |
PT (1) | PT2604695T (pt) |
SI (1) | SI2604695T1 (pt) |
WO (1) | WO2009083210A1 (pt) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL2238255T3 (pl) | 2007-12-27 | 2014-02-28 | Univ Zuerich | Wektory arenawirusowe z defektem replikacji |
WO2011034953A2 (en) * | 2009-09-16 | 2011-03-24 | The Administrators Of The Tulane Educational Fund | Lassa virus-like particles and methods of production thereof |
CN103068835A (zh) * | 2010-06-06 | 2013-04-24 | 西奈山医学院 | 重组rna 病毒及其用途 |
WO2012162428A1 (en) | 2011-05-23 | 2012-11-29 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Prime-boost vaccination for viral infection |
ES2758713T3 (es) * | 2011-07-11 | 2020-05-06 | Inovio Pharmaceuticals Inc | Vacuna de ADN contra el virus de Lassa |
CN112851766A (zh) | 2013-03-13 | 2021-05-28 | 美国政府(由卫生和人类服务部的部长所代表) | 融合前rsv f蛋白和其用途 |
EP2968506B1 (en) | 2013-03-15 | 2019-07-31 | Université de Genève | Anti-mycobacterial vaccines |
PT3077519T (pt) | 2013-12-03 | 2021-05-13 | Hookipa Biotech Ag | Vacinas contra cmv |
US10174317B2 (en) | 2014-02-13 | 2019-01-08 | Synthetic Genomics, Inc. | Recombinant RNA particles and methods of use |
RU2714258C2 (ru) | 2014-02-14 | 2020-02-13 | Селлектис | Клетки для иммунотерапии, сконструированные для нацеливания на антиген, присутствующий одновременно на иммунных клетках и на патологических клетках |
ES2746150T3 (es) | 2014-09-22 | 2020-03-04 | Univ Minnesota | Sistema de genética inversa para el virus Pichindé y métodos de uso |
EP3778903A1 (en) * | 2014-11-13 | 2021-02-17 | Université de Genève | Tri-segmented arenaviruses as vaccine vectors |
DE102015207036A1 (de) | 2015-04-17 | 2016-10-20 | Karl Sebastian Lang | Arenaviren zur Anwendung bei der Behandlung und/oder Vorbeugung von Tumoren sowie Verfahren zur Herstellung von Arenaviren mit (verbesserten) tumorregressiven Eigenschaften |
CN107921117B (zh) * | 2015-06-10 | 2022-06-07 | 霍欧奇帕生物科技有限公司 | Hpv疫苗 |
WO2018045029A1 (en) * | 2016-09-02 | 2018-03-08 | The United States Of America, As Represented By The Secretary Of The Army | Pan south american arenavirus live attenuated vaccine |
EP3371316B1 (en) | 2015-11-04 | 2022-10-19 | Hookipa Biotech GmbH | Vaccines against hepatitis b virus |
AU2016352572B2 (en) | 2015-11-12 | 2023-10-19 | Hookipa Biotech Gmbh | Arenavirus particles as cancer vaccines |
US11260090B2 (en) * | 2016-03-08 | 2022-03-01 | University Of Vermont And State Agricultural College | Modified arenavirus |
SG11201810048VA (en) * | 2016-05-18 | 2018-12-28 | Univ Basel | Tri-segmented pichinde viruses as vaccine vectors |
CA3039356A1 (en) | 2016-11-04 | 2018-05-11 | Hookipa Biotech Gmbh | Replication-deficient arenavirus particles and tri-segmented arenavirus particles as cancer vaccines |
MX2019006349A (es) | 2016-12-16 | 2019-08-22 | Inst Res Biomedicine | Proteinas recombinantes rsv f de prefusion nuevas y usos de las mismas. |
CN110719788A (zh) * | 2017-04-07 | 2020-01-21 | 霍欧奇帕生物科技有限公司 | 治疗实体瘤的沙粒病毒颗粒 |
DE102018215551A1 (de) | 2018-09-12 | 2020-03-12 | Virolutions Biotech Gmbh | Verfahren zur Herstellung eines antitumoralen Arenavirus sowie Arenavirusmutanten |
EP3986455A1 (en) | 2019-06-18 | 2022-04-27 | Janssen Sciences Ireland Unlimited Company | Arenavirus vectors for hepatitis b virus (hbv) vaccines and uses thereof |
US11795210B2 (en) | 2019-07-16 | 2023-10-24 | Gilead Sciences, Inc. | HIV vaccines and methods of making and using |
CN117843811A (zh) | 2019-09-30 | 2024-04-09 | 吉利德科学公司 | Hbv疫苗和治疗hbv的方法 |
WO2021076897A1 (en) * | 2019-10-18 | 2021-04-22 | University Of Virginia Patent Foundation | Compositions and methods for producing enhanced immune responses and rapid antibody production |
EP4055173A1 (en) | 2019-11-07 | 2022-09-14 | Universität Basel Vizerektorat Forschung | Arenaviruses as vectors |
MX2023011054A (es) | 2021-03-23 | 2023-11-22 | Hookipa Biotech Gmbh | Arenavirus utilizados en tratamientos del cáncer de próstata. |
EP4337320A1 (en) | 2021-05-13 | 2024-03-20 | Hookipa Biotech GmbH | Arenaviruses as vectors |
WO2023079153A1 (en) | 2021-11-08 | 2023-05-11 | Hookipa Biotech Gmbh | Modified arenavirus particles expressing mutant kras, mutated cancer driver gene, or tumor-associated antigen as cancer immunotherapies |
WO2023152116A1 (en) | 2022-02-08 | 2023-08-17 | Hookipa Biotech Gmbh | Combination therapy with arenavirus particles and immune checkpoint modulators or cytokines |
CN117343911A (zh) * | 2022-06-28 | 2024-01-05 | 中国科学院上海药物研究所 | 一种缺陷型丝状病毒的制备方法及其应用 |
WO2024015741A1 (en) | 2022-07-12 | 2024-01-18 | Gilead Sciences, Inc. | Hiv immunogenic polypeptides and vaccines and uses thereof |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6015686A (en) | 1993-09-15 | 2000-01-18 | Chiron Viagene, Inc. | Eukaryotic layered vector initiation systems |
US5792462A (en) | 1995-05-23 | 1998-08-11 | University Of North Carolina At Chapel Hill | Alphavirus RNA replicon systems |
US7267823B2 (en) | 1998-06-29 | 2007-09-11 | United States Of America As Represented By The Secretary Of The Army | Ebola peptides and immunogenic compositions containing same |
DE19856463B4 (de) * | 1998-11-26 | 2006-02-02 | Heinrich-Pette-Institut | Retrovirale, mit LCMV pseudotypisierte Hybrid-Vektoren |
JP2000279178A (ja) * | 1999-02-24 | 2000-10-10 | Japan Found Cancer Res | ウイルスベクター |
AU2002331572A1 (en) | 2002-04-17 | 2003-11-03 | Astropower, Inc. | Maximum power sensor for photovoltaic system |
US7135339B2 (en) * | 2003-11-20 | 2006-11-14 | University Of Iowa Research Foundation | Methods for producing and using in vivo pseudotyped retroviruses using envelope glycoproteins from lymphocytic choriomeningitis virus (LCMV) |
WO2005061534A2 (en) | 2003-12-23 | 2005-07-07 | Statens Serum Institut | Improved tuberculosis vaccines |
CA2586620C (en) | 2004-11-16 | 2014-06-03 | Crucell Holland B.V. | Multivalent vaccines comprising recombinant viral vectors |
DE102005006388A1 (de) | 2005-02-11 | 2006-08-24 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Replikationsdefiziente RNA-Viren als Impfstoffe |
US20070005929A1 (en) * | 2005-06-30 | 2007-01-04 | Post Daniel J | Method, system, and article of manufacture for sector mapping in a flash device |
PL2238255T3 (pl) * | 2007-12-27 | 2014-02-28 | Univ Zuerich | Wektory arenawirusowe z defektem replikacji |
CA2823876A1 (en) | 2011-01-07 | 2012-07-12 | Bioscience Slovakia | Viral diagnostics |
EP2968506B1 (en) | 2013-03-15 | 2019-07-31 | Université de Genève | Anti-mycobacterial vaccines |
PT3077519T (pt) | 2013-12-03 | 2021-05-13 | Hookipa Biotech Ag | Vacinas contra cmv |
EP3778903A1 (en) | 2014-11-13 | 2021-02-17 | Université de Genève | Tri-segmented arenaviruses as vaccine vectors |
CN107921117B (zh) | 2015-06-10 | 2022-06-07 | 霍欧奇帕生物科技有限公司 | Hpv疫苗 |
EP3371316B1 (en) | 2015-11-04 | 2022-10-19 | Hookipa Biotech GmbH | Vaccines against hepatitis b virus |
AU2016352572B2 (en) | 2015-11-12 | 2023-10-19 | Hookipa Biotech Gmbh | Arenavirus particles as cancer vaccines |
SG11201810048VA (en) | 2016-05-18 | 2018-12-28 | Univ Basel | Tri-segmented pichinde viruses as vaccine vectors |
CA3039356A1 (en) | 2016-11-04 | 2018-05-11 | Hookipa Biotech Gmbh | Replication-deficient arenavirus particles and tri-segmented arenavirus particles as cancer vaccines |
CN110719788A (zh) | 2017-04-07 | 2020-01-21 | 霍欧奇帕生物科技有限公司 | 治疗实体瘤的沙粒病毒颗粒 |
EP4055173A1 (en) | 2019-11-07 | 2022-09-14 | Universität Basel Vizerektorat Forschung | Arenaviruses as vectors |
PE20240647A1 (es) | 2020-05-29 | 2024-04-04 | Hookipa Biotech Gmbh | Estrategias de tratamiento del cancer mediante el uso de vectores de arenavirus |
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