PT2483305T - Filtração final de imunoglobulina em várias etapas - Google Patents

Filtração final de imunoglobulina em várias etapas

Info

Publication number
PT2483305T
PT2483305T PT107577959T PT10757795T PT2483305T PT 2483305 T PT2483305 T PT 2483305T PT 107577959 T PT107577959 T PT 107577959T PT 10757795 T PT10757795 T PT 10757795T PT 2483305 T PT2483305 T PT 2483305T
Authority
PT
Portugal
Prior art keywords
immunoglobulin
final filtration
multistep
multistep final
filtration
Prior art date
Application number
PT107577959T
Other languages
English (en)
Inventor
Falkenstein Roberto
Schwendner Klaus
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PT2483305T publication Critical patent/PT2483305T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065Purification, fragmentation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/34Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/36Extraction; Separation; Purification by a combination of two or more processes of different types
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oncology (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Water Supply & Treatment (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Fats And Perfumes (AREA)
PT107577959T 2009-10-01 2010-09-29 Filtração final de imunoglobulina em várias etapas PT2483305T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP09012460 2009-10-01

Publications (1)

Publication Number Publication Date
PT2483305T true PT2483305T (pt) 2016-11-04

Family

ID=41466840

Family Applications (1)

Application Number Title Priority Date Filing Date
PT107577959T PT2483305T (pt) 2009-10-01 2010-09-29 Filtração final de imunoglobulina em várias etapas

Country Status (21)

Country Link
US (4) US20120231506A1 (pt)
EP (3) EP3133083B1 (pt)
JP (1) JP5458183B2 (pt)
KR (3) KR101653471B1 (pt)
CN (3) CN102574913A (pt)
AU (1) AU2010302662B2 (pt)
BR (1) BR112012004054B1 (pt)
CA (1) CA2773674C (pt)
CY (1) CY1118577T1 (pt)
DK (1) DK2483305T3 (pt)
ES (2) ES2604103T3 (pt)
HK (2) HK1200178A1 (pt)
HR (2) HRP20161693T1 (pt)
HU (1) HUE030186T2 (pt)
IL (2) IL217626A (pt)
LT (1) LT2483305T (pt)
MX (1) MX342442B (pt)
PL (2) PL2483305T3 (pt)
PT (1) PT2483305T (pt)
SI (2) SI3133083T1 (pt)
WO (1) WO2011039274A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3769083A1 (en) 2018-03-21 2021-01-27 Waters Technologies Corporation Non-antibody high-affinity-based sample preparation, sorbents, devices and methods
CN111007242A (zh) * 2019-12-20 2020-04-14 苏州和迈精密仪器有限公司 基于多层高分子多孔膜的荧光免疫检测方法、装置及应用

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5643566A (en) 1982-09-23 1997-07-01 Cetus Corporation Formulation processes for lipophilic proteins
US4488961A (en) 1982-09-29 1984-12-18 E. I. Du Pont De Nemours And Company One-way filter unit
US4592848A (en) * 1984-12-11 1986-06-03 Pabst Richard E Flow through filter with backflush clearing capability
CS247484B1 (cs) 1985-04-12 1987-01-15 Eva Hamsikova Způsob přípravy imunoglobulinu proti lidským Iymfocytům
WO1989006692A1 (en) 1988-01-12 1989-07-27 Genentech, Inc. Method of treating tumor cells by inhibiting growth factor receptor function
DE3818860A1 (de) 1988-06-03 1989-12-07 Seitz Filter Werke Filterelement
AU675916B2 (en) 1991-06-14 1997-02-27 Genentech Inc. Method for making humanized antibodies
DE4204444C1 (pt) 1992-02-14 1993-05-19 Krankenhausentsorgungs Gmbh, 1000 Berlin, De
AU716785B2 (en) 1995-07-27 2000-03-09 Genentech Inc. Stabile isotonic lyophilized protein formulation
IL130061A (en) 1996-11-27 2001-09-13 Genentech Inc Affinity purification of polypeptide on protein a matrix
ATE370961T1 (de) 1998-05-06 2007-09-15 Genentech Inc Reinigung von antikörpern durch ionenaustauschchromatographie
US6984494B2 (en) * 2000-08-15 2006-01-10 Genentech, Inc. Analytical method
WO2003066662A2 (en) 2002-02-05 2003-08-14 Genentech, Inc. Protein purification
CN1671741A (zh) * 2002-06-21 2005-09-21 拜奥根Idec公司 浓缩抗体的缓冲剂制剂及其使用方法
CA2501068C (en) * 2002-10-04 2014-12-16 Kirin Beer Kabushiki Kaisha Human artificial chromosome (hac) vector
JPWO2004087761A1 (ja) 2003-03-31 2006-07-27 麒麟麦酒株式会社 ヒトモノクローナル抗体およびヒトポリクローナル抗体の精製
GB0316560D0 (en) * 2003-07-15 2003-08-20 Chiron Srl Vesicle filtration
US20060034850A1 (en) * 2004-05-27 2006-02-16 Weidanz Jon A Antibodies as T cell receptor mimics, methods of production and uses thereof
EP1786273B1 (en) * 2004-08-20 2018-11-14 ProMetic BioSciences Ltd. Sequential protein isolation and purification schemes by affinity chromatography
US20060051347A1 (en) * 2004-09-09 2006-03-09 Winter Charles M Process for concentration of antibodies and therapeutic products thereof
CA2586130A1 (en) * 2004-11-22 2006-05-26 Oxygenix Co., Ltd. Reagent containing oxygen isotope-labeled hemoglobin for examining vital tissue and method of producing the same
TWI306862B (en) 2005-01-03 2009-03-01 Hoffmann La Roche Antibodies against il-13 receptor alpha 1 and uses thereof
NZ560844A (en) * 2005-03-08 2008-08-29 Pharmacia & Upjohn Co Llc Anti-MAdCAM antibody compositions
EP1923072A4 (en) 2005-08-09 2010-03-03 Takeda Pharmaceutical MEDICINE FOR PROPHYLAXIS / TREATMENT OF CANCER
AU2007351548B2 (en) * 2006-11-01 2012-08-16 Biogen Ma Inc. Method of isolating biomacromolecules using low pH and divalent cations
CN101754977B (zh) * 2007-07-17 2013-07-17 弗·哈夫曼-拉罗切有限公司 可变切向流过滤
AR067536A1 (es) 2007-07-17 2009-10-14 Hoffmann La Roche Metodo para obtener una eritropoyetina mono-pegilada en una forma sustancialmente homogenea
WO2009058769A1 (en) 2007-10-30 2009-05-07 Schering Corporation Purification of antibodies containing hydrophobic variants
EP2346900A1 (en) 2008-10-29 2011-07-27 Wyeth LLC Methods for purification of single domain antigen binding molecules
RU2632568C2 (ru) * 2012-10-30 2017-10-05 Ф.Хоффманн-Ля Рош Аг Очистка полипептидов с использованием двухстадийной ультрафильтрации в тангенциальном потоке

Also Published As

Publication number Publication date
US20120231506A1 (en) 2012-09-13
US11891430B2 (en) 2024-02-06
EP2483305A1 (en) 2012-08-08
PL3133083T3 (pl) 2020-09-07
HK1210183A1 (en) 2016-04-15
HUE030186T2 (en) 2017-04-28
KR20160104739A (ko) 2016-09-05
KR20140091763A (ko) 2014-07-22
CN104610447A (zh) 2015-05-13
US20240132574A1 (en) 2024-04-25
DK2483305T3 (en) 2016-10-24
CN102574913A (zh) 2012-07-11
HK1200178A1 (en) 2015-07-31
LT2483305T (lt) 2016-11-25
JP5458183B2 (ja) 2014-04-02
JP2013505733A (ja) 2013-02-21
CA2773674C (en) 2017-08-29
KR101653471B1 (ko) 2016-09-01
IL217626A (en) 2017-12-31
CA2773674A1 (en) 2011-04-07
US20200291097A1 (en) 2020-09-17
CN103980346A (zh) 2014-08-13
MX342442B (es) 2016-09-29
MX2012003727A (es) 2012-04-30
EP3133083B1 (en) 2020-02-19
BR112012004054A2 (pt) 2020-08-11
CY1118577T1 (el) 2017-07-12
EP3715369A1 (en) 2020-09-30
US20240228589A9 (en) 2024-07-11
ES2604103T3 (es) 2017-03-03
KR20120053522A (ko) 2012-05-25
KR101718301B1 (ko) 2017-03-20
AU2010302662A1 (en) 2012-02-09
BR112012004054B1 (pt) 2021-09-08
HRP20161693T1 (hr) 2017-02-24
SI2483305T1 (sl) 2017-01-31
KR101508044B1 (ko) 2015-04-07
WO2011039274A1 (en) 2011-04-07
IL255658A (en) 2018-01-31
SI3133083T1 (sl) 2020-07-31
PL2483305T3 (pl) 2017-03-31
US20180009878A1 (en) 2018-01-11
ES2787403T3 (es) 2020-10-16
AU2010302662B2 (en) 2015-11-26
HRP20200588T1 (hr) 2020-07-10
EP3133083A1 (en) 2017-02-22
EP2483305B1 (en) 2016-09-21

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