PT2424510E - Composição de células hepáticas encapsuladas - Google Patents

Composição de células hepáticas encapsuladas

Info

Publication number
PT2424510E
PT2424510E PT107213043T PT10721304T PT2424510E PT 2424510 E PT2424510 E PT 2424510E PT 107213043 T PT107213043 T PT 107213043T PT 10721304 T PT10721304 T PT 10721304T PT 2424510 E PT2424510 E PT 2424510E
Authority
PT
Portugal
Prior art keywords
liver cell
cell composition
encapsulated liver
encapsulated
erythropoietin
Prior art date
Application number
PT107213043T
Other languages
English (en)
Inventor
Krasimira Aleksandrova
Peter Pediaditakis
Jo Salisbury
Wolfgang Ruedinger
Original Assignee
Cytonet Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytonet Gmbh & Co Kg filed Critical Cytonet Gmbh & Co Kg
Publication of PT2424510E publication Critical patent/PT2424510E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/407—Liver; Hepatocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1816—Erythropoietin [EPO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Inorganic Chemistry (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT107213043T 2009-04-27 2010-04-27 Composição de células hepáticas encapsuladas PT2424510E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12/430,330 US20100272816A1 (en) 2009-04-27 2009-04-27 Microcapsules comprising liver cells and erythropoietin, methods for preparing said microcapsules and methods for treating a patient comprising applying said microcapsules to the patient

Publications (1)

Publication Number Publication Date
PT2424510E true PT2424510E (pt) 2013-10-14

Family

ID=42790675

Family Applications (1)

Application Number Title Priority Date Filing Date
PT107213043T PT2424510E (pt) 2009-04-27 2010-04-27 Composição de células hepáticas encapsuladas

Country Status (26)

Country Link
US (3) US20100272816A1 (pt)
EP (1) EP2424510B1 (pt)
JP (1) JP5702771B2 (pt)
KR (1) KR101372384B1 (pt)
CN (2) CN103638002B (pt)
AU (1) AU2010243888C1 (pt)
BR (1) BRPI1014835A8 (pt)
CL (1) CL2011002689A1 (pt)
CY (1) CY1114464T1 (pt)
DK (1) DK2424510T3 (pt)
ES (1) ES2431297T3 (pt)
HK (1) HK1165278A1 (pt)
HR (1) HRP20130963T1 (pt)
IL (1) IL215887A (pt)
MX (1) MX2011010993A (pt)
NZ (1) NZ595511A (pt)
PL (1) PL2424510T3 (pt)
PT (1) PT2424510E (pt)
RS (1) RS52989B (pt)
RU (2) RU2564924C2 (pt)
SG (1) SG175792A1 (pt)
SI (1) SI2424510T1 (pt)
SM (1) SMT201300111B (pt)
UA (1) UA99686C2 (pt)
WO (1) WO2010124837A2 (pt)
ZA (1) ZA201106817B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106134070B (zh) * 2014-07-25 2018-05-22 积水化学工业株式会社 一种包括二次电池的发电装置
WO2016183231A1 (en) 2015-05-12 2016-11-17 Baker Group, LLP Method and system for a bioartificial organ
RU2618989C1 (ru) * 2016-03-09 2017-05-11 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Способ лечения печеночной недостаточности
CN108138134B (zh) * 2016-09-14 2019-05-10 四川蓝光英诺生物科技股份有限公司 人工组织前体及制备其的方法
US11439731B2 (en) 2016-09-14 2022-09-13 Revotek Co., Ltd. Artificial tissue progenitor and method for preparing the same
WO2018093069A1 (ko) * 2016-11-15 2018-05-24 광주과학기술원 세포 3d 배양 방법
CN113573746A (zh) * 2019-03-20 2021-10-29 公立大学法人横滨市立大学 包覆固定剂

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5455790A (en) 1977-10-05 1979-05-04 Tomoyuki Tajima Production of erythropoetin
JPS6045849B2 (ja) 1980-08-25 1985-10-12 林原 健 ヒトエリトロポエチンの製造方法
NZ210501A (en) 1983-12-13 1991-08-27 Kirin Amgen Inc Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence
US4956128A (en) * 1984-05-25 1990-09-11 Connaught Laboratories Limited Droplet generation
IL77081A (en) 1984-12-04 1999-10-28 Genetics Inst AND sequence encoding human erythropoietin, a process for its preparation and a pharmacological preparation of human erythropoietin
US5084350A (en) * 1990-02-16 1992-01-28 The Royal Institution For The Advance Of Learning (Mcgill University) Method for encapsulating biologically active material including cells
HUT73876A (en) 1993-04-29 1996-10-28 Abbott Lab Erythropoietin analog compositions and methods
IL110669A (en) 1993-08-17 2008-11-26 Kirin Amgen Inc Erythropoietin analogs
RU94030310A (ru) * 1994-08-16 1996-08-10 Молдавский научно-исследовательский институт профилактической и клинической медицины МЗ Республики Молдова (MD) Способ культивирования клеток человека и животных
US6281015B1 (en) * 1994-12-16 2001-08-28 Children's Medical Center Corp. Localized delivery of factors enhancing survival of transplanted cells
JP2006506971A (ja) 2002-07-19 2006-03-02 ヴェスタ セラピューティクス，インコーポレーテッド 肝性幹／前駆細胞を含む生存能のあるヒト肝臓細胞を得る方法
AU2004309083B2 (en) 2003-12-30 2010-11-11 Augustinus Bader Tissue regeneration method
CA2561725A1 (en) * 2004-03-30 2005-10-13 Fac8Cell Pty Limited Culture and use of cells that secrete liver secretory factors
RU2429864C2 (ru) 2005-10-21 2011-09-27 Ливинг Селл Продактс Пти Лимитед Система инкапсуляции

Also Published As

Publication number Publication date
US9517247B2 (en) 2016-12-13
SI2424510T1 (sl) 2013-11-29
CN103638002A (zh) 2014-03-19
KR101372384B1 (ko) 2014-03-12
WO2010124837A2 (en) 2010-11-04
CN103638002B (zh) 2016-05-18
RS52989B (en) 2014-02-28
AU2010243888C1 (en) 2014-01-23
KR20120014171A (ko) 2012-02-16
IL215887A0 (en) 2012-01-31
JP2012524739A (ja) 2012-10-18
SG175792A1 (en) 2011-12-29
RU2500390C2 (ru) 2013-12-10
PL2424510T3 (pl) 2013-12-31
US20120093937A1 (en) 2012-04-19
NZ595511A (en) 2013-02-22
BRPI1014835A8 (pt) 2018-02-14
CN102413820B (zh) 2013-09-25
CY1114464T1 (el) 2016-10-05
US8535923B2 (en) 2013-09-17
CL2011002689A1 (es) 2012-04-27
ES2431297T3 (es) 2013-11-25
JP5702771B2 (ja) 2015-04-15
DK2424510T3 (da) 2013-10-07
ZA201106817B (en) 2012-11-28
RU2564924C2 (ru) 2015-10-10
RU2011148106A (ru) 2013-06-10
SMT201300111B (it) 2013-11-08
AU2010243888A1 (en) 2011-10-27
EP2424510B1 (en) 2013-07-17
MX2011010993A (es) 2011-11-02
AU2010243888B2 (en) 2013-08-22
WO2010124837A3 (en) 2011-02-10
US20140017305A1 (en) 2014-01-16
BRPI1014835A2 (pt) 2016-04-12
US20100272816A1 (en) 2010-10-28
HRP20130963T1 (hr) 2013-11-22
CN102413820A (zh) 2012-04-11
IL215887A (en) 2016-05-31
UA99686C2 (ru) 2012-09-10
RU2013143436A (ru) 2015-03-27
EP2424510A2 (en) 2012-03-07
HK1165278A1 (en) 2012-10-05

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