BRPI1014835A8 - Composição de células hepáticas encapsuladas - Google Patents
Composição de células hepáticas encapsuladasInfo
- Publication number
- BRPI1014835A8 BRPI1014835A8 BRPI1014835A BRPI1014835A BRPI1014835A8 BR PI1014835 A8 BRPI1014835 A8 BR PI1014835A8 BR PI1014835 A BRPI1014835 A BR PI1014835A BR PI1014835 A BRPI1014835 A BR PI1014835A BR PI1014835 A8 BRPI1014835 A8 BR PI1014835A8
- Authority
- BR
- Brazil
- Prior art keywords
- liver cells
- composition
- encapsulated liver
- encapsulated
- amount
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/407—Liver; Hepatocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- Developmental Biology & Embryology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Inorganic Chemistry (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
COMPOSIÇÃO DE CÉLULAS HEPÁTICAS ENCAPSULADAS Microcápsulas que compreendem uma cápsula encapsulando uma suspensão de uma quantidade terapeuticamente eficaz de células hepéticas em contato físico com uma quantidade de eritropoietina que estimula células do fígado.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/430,330 US20100272816A1 (en) | 2009-04-27 | 2009-04-27 | Microcapsules comprising liver cells and erythropoietin, methods for preparing said microcapsules and methods for treating a patient comprising applying said microcapsules to the patient |
PCT/EP2010/002563 WO2010124837A2 (en) | 2009-04-27 | 2010-04-27 | Encapsulated liver cell composition |
Publications (2)
Publication Number | Publication Date |
---|---|
BRPI1014835A2 BRPI1014835A2 (pt) | 2016-04-12 |
BRPI1014835A8 true BRPI1014835A8 (pt) | 2018-02-14 |
Family
ID=42790675
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI1014835A BRPI1014835A8 (pt) | 2009-04-27 | 2010-04-27 | Composição de células hepáticas encapsuladas |
Country Status (26)
Country | Link |
---|---|
US (3) | US20100272816A1 (pt) |
EP (1) | EP2424510B1 (pt) |
JP (1) | JP5702771B2 (pt) |
KR (1) | KR101372384B1 (pt) |
CN (2) | CN103638002B (pt) |
AU (1) | AU2010243888C1 (pt) |
BR (1) | BRPI1014835A8 (pt) |
CL (1) | CL2011002689A1 (pt) |
CY (1) | CY1114464T1 (pt) |
DK (1) | DK2424510T3 (pt) |
ES (1) | ES2431297T3 (pt) |
HK (1) | HK1165278A1 (pt) |
HR (1) | HRP20130963T1 (pt) |
IL (1) | IL215887A (pt) |
MX (1) | MX2011010993A (pt) |
NZ (1) | NZ595511A (pt) |
PL (1) | PL2424510T3 (pt) |
PT (1) | PT2424510E (pt) |
RS (1) | RS52989B (pt) |
RU (2) | RU2564924C2 (pt) |
SG (1) | SG175792A1 (pt) |
SI (1) | SI2424510T1 (pt) |
SM (1) | SMT201300111B (pt) |
UA (1) | UA99686C2 (pt) |
WO (1) | WO2010124837A2 (pt) |
ZA (1) | ZA201106817B (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106134070B (zh) * | 2014-07-25 | 2018-05-22 | 积水化学工业株式会社 | 一种包括二次电池的发电装置 |
WO2016183231A1 (en) | 2015-05-12 | 2016-11-17 | Baker Group, LLP | Method and system for a bioartificial organ |
RU2618989C1 (ru) * | 2016-03-09 | 2017-05-11 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) | Способ лечения печеночной недостаточности |
CN108138134B (zh) * | 2016-09-14 | 2019-05-10 | 四川蓝光英诺生物科技股份有限公司 | 人工组织前体及制备其的方法 |
US11439731B2 (en) | 2016-09-14 | 2022-09-13 | Revotek Co., Ltd. | Artificial tissue progenitor and method for preparing the same |
WO2018093069A1 (ko) * | 2016-11-15 | 2018-05-24 | 광주과학기술원 | 세포 3d 배양 방법 |
CN113573746A (zh) * | 2019-03-20 | 2021-10-29 | 公立大学法人横滨市立大学 | 包覆固定剂 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5455790A (en) | 1977-10-05 | 1979-05-04 | Tomoyuki Tajima | Production of erythropoetin |
JPS6045849B2 (ja) | 1980-08-25 | 1985-10-12 | 林原 健 | ヒトエリトロポエチンの製造方法 |
NZ210501A (en) | 1983-12-13 | 1991-08-27 | Kirin Amgen Inc | Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence |
US4956128A (en) * | 1984-05-25 | 1990-09-11 | Connaught Laboratories Limited | Droplet generation |
IL77081A (en) | 1984-12-04 | 1999-10-28 | Genetics Inst | AND sequence encoding human erythropoietin, a process for its preparation and a pharmacological preparation of human erythropoietin |
US5084350A (en) * | 1990-02-16 | 1992-01-28 | The Royal Institution For The Advance Of Learning (Mcgill University) | Method for encapsulating biologically active material including cells |
HUT73876A (en) | 1993-04-29 | 1996-10-28 | Abbott Lab | Erythropoietin analog compositions and methods |
IL110669A (en) | 1993-08-17 | 2008-11-26 | Kirin Amgen Inc | Erythropoietin analogs |
RU94030310A (ru) * | 1994-08-16 | 1996-08-10 | Молдавский научно-исследовательский институт профилактической и клинической медицины МЗ Республики Молдова (MD) | Способ культивирования клеток человека и животных |
US6281015B1 (en) * | 1994-12-16 | 2001-08-28 | Children's Medical Center Corp. | Localized delivery of factors enhancing survival of transplanted cells |
JP2006506971A (ja) | 2002-07-19 | 2006-03-02 | ヴェスタ セラピューティクス,インコーポレーテッド | 肝性幹/前駆細胞を含む生存能のあるヒト肝臓細胞を得る方法 |
AU2004309083B2 (en) | 2003-12-30 | 2010-11-11 | Augustinus Bader | Tissue regeneration method |
CA2561725A1 (en) * | 2004-03-30 | 2005-10-13 | Fac8Cell Pty Limited | Culture and use of cells that secrete liver secretory factors |
RU2429864C2 (ru) | 2005-10-21 | 2011-09-27 | Ливинг Селл Продактс Пти Лимитед | Система инкапсуляции |
-
2009
- 2009-04-27 US US12/430,330 patent/US20100272816A1/en not_active Abandoned
-
2010
- 2010-04-27 AU AU2010243888A patent/AU2010243888C1/en not_active Ceased
- 2010-04-27 EP EP10721304.3A patent/EP2424510B1/en active Active
- 2010-04-27 JP JP2012506407A patent/JP5702771B2/ja not_active Expired - Fee Related
- 2010-04-27 PL PL10721304T patent/PL2424510T3/pl unknown
- 2010-04-27 RU RU2013143436/15A patent/RU2564924C2/ru active
- 2010-04-27 BR BRPI1014835A patent/BRPI1014835A8/pt not_active Application Discontinuation
- 2010-04-27 SI SI201030374T patent/SI2424510T1/sl unknown
- 2010-04-27 RS RS20130454A patent/RS52989B/en unknown
- 2010-04-27 UA UAA201112582A patent/UA99686C2/ru unknown
- 2010-04-27 RU RU2011148106/15A patent/RU2500390C2/ru active
- 2010-04-27 ES ES10721304T patent/ES2431297T3/es active Active
- 2010-04-27 NZ NZ595511A patent/NZ595511A/xx not_active IP Right Cessation
- 2010-04-27 KR KR1020117028010A patent/KR101372384B1/ko active IP Right Grant
- 2010-04-27 SG SG2011078375A patent/SG175792A1/en unknown
- 2010-04-27 DK DK10721304.3T patent/DK2424510T3/da active
- 2010-04-27 MX MX2011010993A patent/MX2011010993A/es active IP Right Grant
- 2010-04-27 CN CN201310424282.3A patent/CN103638002B/zh not_active Expired - Fee Related
- 2010-04-27 WO PCT/EP2010/002563 patent/WO2010124837A2/en active Application Filing
- 2010-04-27 PT PT107213043T patent/PT2424510E/pt unknown
- 2010-04-27 CN CN2010800188449A patent/CN102413820B/zh not_active Expired - Fee Related
- 2010-04-27 US US13/263,352 patent/US8535923B2/en not_active Expired - Fee Related
-
2011
- 2011-09-19 ZA ZA2011/06817A patent/ZA201106817B/en unknown
- 2011-10-24 IL IL215887A patent/IL215887A/en active IP Right Grant
- 2011-10-27 CL CL2011002689A patent/CL2011002689A1/es unknown
-
2012
- 2012-06-15 HK HK12105890.6A patent/HK1165278A1/xx not_active IP Right Cessation
-
2013
- 2013-09-16 US US14/027,932 patent/US9517247B2/en active Active
- 2013-10-04 SM SM201300111T patent/SMT201300111B/xx unknown
- 2013-10-09 CY CY20131100876T patent/CY1114464T1/el unknown
- 2013-10-10 HR HRP20130963AT patent/HRP20130963T1/hr unknown
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Legal Events
Date | Code | Title | Description |
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B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 3A ANUIDADE. |
|
B08G | Application fees: restoration [chapter 8.7 patent gazette] | ||
B25A | Requested transfer of rights approved |
Owner name: PROMETHERA BIOSCIENCES SA (BE) |
|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL |