PT2371854E - Indução da imunidade tumoral por variantes da proteína de ligação ao folato - Google Patents

Indução da imunidade tumoral por variantes da proteína de ligação ao folato Download PDF

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Publication number
PT2371854E
PT2371854E PT110047149T PT11004714T PT2371854E PT 2371854 E PT2371854 E PT 2371854E PT 110047149 T PT110047149 T PT 110047149T PT 11004714 T PT11004714 T PT 11004714T PT 2371854 E PT2371854 E PT 2371854E
Authority
PT
Portugal
Prior art keywords
variants
induction
binding protein
tumor immunity
folate binding
Prior art date
Application number
PT110047149T
Other languages
English (en)
Inventor
George E Peoples
Constantin G Ioannides
Original Assignee
Jackson H M Found Military Med
Univ Texas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jackson H M Found Military Med, Univ Texas filed Critical Jackson H M Found Military Med
Publication of PT2371854E publication Critical patent/PT2371854E/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A61K39/17—Newcastle disease virus
PT110047149T 2001-03-09 2002-03-08 Indução da imunidade tumoral por variantes da proteína de ligação ao folato PT2371854E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27467601P 2001-03-09 2001-03-09

Publications (1)

Publication Number Publication Date
PT2371854E true PT2371854E (pt) 2014-08-25

Family

ID=23049174

Family Applications (1)

Application Number Title Priority Date Filing Date
PT110047149T PT2371854E (pt) 2001-03-09 2002-03-08 Indução da imunidade tumoral por variantes da proteína de ligação ao folato

Country Status (9)

Country Link
US (5) US7547759B2 (pt)
EP (2) EP1472337A4 (pt)
JP (3) JP4401075B2 (pt)
CA (1) CA2440610C (pt)
DK (1) DK2371854T3 (pt)
ES (1) ES2502366T3 (pt)
PT (1) PT2371854E (pt)
SI (1) SI2371854T1 (pt)
WO (1) WO2002072766A2 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7547759B2 (en) 2001-03-09 2009-06-16 Board Of Regents, The University Of Texas System Induction of tumor immunity by variants of folate binding protein
WO2006097682A1 (en) * 2005-03-18 2006-09-21 Ucl Business Plc Mechano growth factor peptides and their use
EP1907852A4 (en) 2005-07-06 2011-07-06 Jackson H M Found Military Med STABLE QUANTIFICATION AND IDENTIFICATION OF IMMUNE RESPONSE LEVELS WITH NON-NULL BACKGROUND PEPTIDES
CA2621083C (en) 2005-08-30 2017-04-11 University Of Miami Immunomodulating tumor necrosis factor receptor 25 (tnfr25) agonists, antagonists and immunotoxins
CA2685300C (en) 2006-06-01 2017-01-03 Mayo Foundation For Medical Education And Research Immunity to folate receptors
US9993538B2 (en) 2015-05-29 2018-06-12 Galena Biopharma, Inc. Peptide vaccine therapy for treatment of FRα-expressing tumors
EP3463438B1 (en) 2016-05-31 2022-04-06 The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. Vaccine therapy for treatment of endometrial and ovarian cancer
EP3290395A1 (en) * 2016-09-02 2018-03-07 Paques I.P. B.V. Anaerobic purification device with variable water column
EP3583218A4 (en) * 2017-02-17 2020-12-30 Purdue Research Foundation TARGETED ACTIVE SUBSTANCE RELEASE ON LIGAND PAYLOAD BASIS FOR CELL THERAPY

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3826364A (en) 1972-05-22 1974-07-30 Univ Leland Stanford Junior Particle sorting method and apparatus
US4284412A (en) 1979-07-13 1981-08-18 Ortho Diagnostics, Inc. Method and apparatus for automated identification and enumeration of specified blood cell subclasses
US4596792A (en) 1981-09-04 1986-06-24 The Regents Of The University Of California Safe vaccine for hepatitis containing polymerized serum albumin
US4498766A (en) 1982-03-25 1985-02-12 Becton, Dickinson And Company Light beam focal spot elongation in flow cytometry devices
JPS5938877A (ja) 1982-08-30 1984-03-02 Musashi Eng Kk 紙葉判別方法
US4599230A (en) 1984-03-09 1986-07-08 Scripps Clinic And Research Foundation Synthetic hepatitis B virus vaccine including both T cell and B cell determinants
US5384253A (en) 1990-12-28 1995-01-24 Dekalb Genetics Corporation Genetic transformation of maize cells by electroporation of cells pretreated with pectin degrading enzymes
US6419931B1 (en) * 1991-08-26 2002-07-16 Epimmune Inc. Compositions and methods for eliciting CTL immunity
US5801005A (en) 1993-03-17 1998-09-01 University Of Washington Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated
US6514942B1 (en) * 1995-03-14 2003-02-04 The Board Of Regents, The University Of Texas System Methods and compositions for stimulating T-lymphocytes
US5830755A (en) 1995-03-27 1998-11-03 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services T-cell receptors and their use in therapeutic and diagnostic methods
US6013516A (en) 1995-10-06 2000-01-11 The Salk Institute For Biological Studies Vector and method of use for nucleic acid delivery to non-dividing cells
EP0871492B1 (en) * 1996-01-05 2003-11-26 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services Mesothelium antigen and methods and kits for targeting it
US5994136A (en) 1997-12-12 1999-11-30 Cell Genesys, Inc. Method and means for producing high titer, safe, recombinant lentivirus vectors
EA013944B1 (ru) * 2001-02-20 2010-08-30 Орто-Макнейл Фармасьютикал, Инк. Способ получения неприродной антигенпрезентирующей клеточной линии и применение линии для лечения опухолей
US7547759B2 (en) * 2001-03-09 2009-06-16 Board Of Regents, The University Of Texas System Induction of tumor immunity by variants of folate binding protein
US9993538B2 (en) * 2015-05-29 2018-06-12 Galena Biopharma, Inc. Peptide vaccine therapy for treatment of FRα-expressing tumors

Also Published As

Publication number Publication date
EP2371854A2 (en) 2011-10-05
US20090227510A1 (en) 2009-09-10
EP1472337A4 (en) 2008-02-27
US8815256B2 (en) 2014-08-26
JP2012097111A (ja) 2012-05-24
US8258261B2 (en) 2012-09-04
WO2002072766A2 (en) 2002-09-19
ES2502366T3 (es) 2014-10-03
CA2440610C (en) 2011-07-12
JP4401075B2 (ja) 2010-01-20
US7547759B2 (en) 2009-06-16
WO2002072766A8 (en) 2004-09-02
JP2009114190A (ja) 2009-05-28
JP5017238B2 (ja) 2012-09-05
SI2371854T1 (sl) 2014-09-30
CA2440610A1 (en) 2002-09-19
US20130039935A1 (en) 2013-02-14
DK2371854T3 (da) 2014-08-11
EP1472337A1 (en) 2004-11-03
US20030185840A1 (en) 2003-10-02
EP2371854A3 (en) 2011-12-21
US20150175658A1 (en) 2015-06-25
US20180194806A1 (en) 2018-07-12
US9562070B2 (en) 2017-02-07
EP2371854B1 (en) 2014-05-07
JP2004532825A (ja) 2004-10-28

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